Zobrazeno 1 - 10
of 42
pro vyhledávání: '"host shut-off"'
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 13 (2023)
Live-attenuated influenza A viruses (LAIV) may be superior to inactivated or subunit vaccines since they can be administered via mucosal routes to induce local immunity in the respiratory tract. In addition, LAIV are expected to trigger stronger T-ce
Externí odkaz:
https://doaj.org/article/6cb14645d78f4ec2a7dfd5002fea4b85
Autor:
Theodore G. Liou, Frederick R. Adler, Barbara C. Cahill, David R. Cox, James E. Cox, Garett J. Grant, Kimberly E. Hanson, Stephen C. Hartsell, Nathan D. Hatton, My N. Helms, Judy L. Jensen, Christiana Kartsonaki, Yanping Li, Daniel T. Leung, James E. Marvin, Elizabeth A. Middleton, Sandra M. Osburn‐Staker, Kristyn A. Packer, Salika M. Shakir, Anne B. Sturrock, Keith D. Tardif, Kristi J. Warren, Lindsey J. Waddoups, Lisa J. Weaver, Elizabeth Zimmerman, Robert Paine III
Publikováno v:
Physiological Reports, Vol 9, Iss 4, Pp n/a-n/a (2021)
Abstract COVID‐19 causes severe disease with poor outcomes. We tested the hypothesis that early SARS‐CoV‐2 viral infection disrupts innate immune responses. These changes may be important for understanding subsequent clinical outcomes. We obtai
Externí odkaz:
https://doaj.org/article/cad182d307d642e6bf3b48dd61e5b619
Publikováno v:
Viruses, Vol 12, Iss 5, p 536 (2020)
Viruses must hijack cellular translation machinery to express viral genes. In many cases, this is impeded by cellular stress responses. These stress responses result in the global inhibition of translation and the storage of stalled mRNAs, into RNA-p
Externí odkaz:
https://doaj.org/article/334573c5adcd42bba926d4fdd2528622
Autor:
Xia Zhao, Canhuang Chen, Xingyu Jiang, Wei Shen, Guangtao Huang, Shuai Le, Shuguang Lu, Qingshan Ni, Lingyun Zou, Ming Li, Yan Zhao, Jing Wang, Xiancai Rao, Fuquan Hu, Yinling Tan
Publikováno v:
Frontiers in Microbiology, Vol 7 (2016)
The impact of phage infection on the host cell is severe. In order to take over the cellular machinery, some phage proteins were produced to shut off the host biosynthesis early in the phage infection. The discovery and identification of these phage-
Externí odkaz:
https://doaj.org/article/e9bf67d1c5f345a59b0ee04c3658d2a2
Akademický článek
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Autor:
Elizabeth A. Middleton, Theodore G. Liou, Kristi J. Warren, Garett J Grant, David Cox, Judy L. Jensen, Sandra M Osburn-Staker, Elizabeth Zimmerman, Salika M. Shakir, Robert Paine, James E. Marvin, Anne Sturrock, Lisa J Weaver, James E. Cox, Kimberly E. Hanson, Christiana Kartsonaki, Frederick R. Adler, Yanping Li, Nathan D. Hatton, Stephen C. Hartsell, My N Helms, Kristyn A Packer, Daniel T. Leung, Barbara C. Cahill, Keith D. Tardif, Lindsey J Waddoups
Publikováno v:
Physiological Reports, Vol 9, Iss 4, Pp n/a-n/a (2021)
Physiological Reports
Physiological Reports
COVID‐19 causes severe disease with poor outcomes. We tested the hypothesis that early SARS‐CoV‐2 viral infection disrupts innate immune responses. These changes may be important for understanding subsequent clinical outcomes. We obtained resid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4625954608df82e43175aa8f2a159157
https://doaj.org/article/cad182d307d642e6bf3b48dd61e5b619
https://doaj.org/article/cad182d307d642e6bf3b48dd61e5b619
Autor:
Kristina M. Herbert, Anita Nag
Publikováno v:
Viruses, Vol 8, Iss 6, p 154 (2016)
Viral infection initiates an array of changes in host gene expression. Many viruses dampen host protein expression and attempt to evade the host anti-viral defense machinery. Host gene expression is suppressed at several stages of host messenger RNA
Externí odkaz:
https://doaj.org/article/9e7d99614b2d4f0b8319c64945f9fecb
Autor:
Jelke J. Fros, Gorben P. Pijlman
Publikováno v:
Viruses, Vol 8, Iss 6, p 166 (2016)
Alphaviruses cause debilitating disease in humans and animals and are transmitted by blood-feeding arthropods, typically mosquitoes. With a traditional focus on two models, Sindbis virus and Semliki Forest virus, alphavirus research has significantly
Externí odkaz:
https://doaj.org/article/f8ae777f432c482a929390c45bc1e8ac
Publikováno v:
Neurobiology of Disease, Vol 1, Iss 1, Pp 83-94 (1994)
Infection of non-neuronal cell types with herpes simplex virus type 1 (HSV-1) results in the degradation of host mRNA (Kwong & Frenkel 1987) and a shutoff in host protein synthesis (Roizmanet al.1965). This effect is mediated by a virion associated p
Externí odkaz:
https://doaj.org/article/2710c1549ac2413aad642b284f9bd552
Publikováno v:
Viruses
Volume 12
Issue 5
Viruses, Vol 12, Iss 536, p 536 (2020)
Volume 12
Issue 5
Viruses, Vol 12, Iss 536, p 536 (2020)
Viruses must hijack cellular translation machinery to express viral genes. In many cases, this is impeded by cellular stress responses. These stress responses result in the global inhibition of translation and the storage of stalled mRNAs, into RNA-p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62ce347bef9b1d1a7c383091df4725f3
