Zobrazeno 1 - 10
of 127
pro vyhledávání: '"host restriction factors"'
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Different host proteins target different HIV proteins and antagonize their functions, depending on the stage of the HIV life cycle and the stage of infection. Concurrently, HIV proteins also target and antagonize various different host proteins to fa
Externí odkaz:
https://doaj.org/article/a4cad7f2411d42699f7c444da7b5dd6f
Publikováno v:
Viruses, Vol 16, Iss 5, p 764 (2024)
The hepatitis B virus (HBV) infects hepatocytes and hijacks host cellular mechanisms for its replication. Host proteins can be frontline effectors of the cell’s defense and restrict viral replication by impeding multiple steps during its intracellu
Externí odkaz:
https://doaj.org/article/249a04dd8e184ee8acb66971ab7e0917
Publikováno v:
Biomolecules, Vol 13, Iss 6, p 937 (2023)
Interferon-induced transmembrane proteins (IFITMs) block the fusion of diverse enveloped viruses, likely through increasing the cell membrane’s rigidity. Previous studies have reported that the antiviral activity of the IFITM family member, IFITM3,
Externí odkaz:
https://doaj.org/article/71f9c49edffc45c59280693332c68589
Autor:
Ana Sofia Coroadinha
Publikováno v:
Cells, Vol 12, Iss 5, p 732 (2023)
Gene therapy relies on the delivery of genetic material to the patient’s cells in order to provide a therapeutic treatment. Two of the currently most used and efficient delivery systems are the lentiviral (LV) and adeno-associated virus (AAV) vecto
Externí odkaz:
https://doaj.org/article/d8345103f16d40d8b310fc02b6a836ef
Publikováno v:
Frontiers in Virology, Vol 2 (2022)
Human Endogenous Retroviruses (HERVs) constitute up to 8% of the human genome and have been emerging as important modulators of the immune system, being associated with cancer, autoimmunity and infectious diseases. Here, we investigated the expressio
Externí odkaz:
https://doaj.org/article/ebeb65a3498c466986eb8ccdb38bf6cd
Autor:
Nazanin Mohammadzadeh, Na Zhang, William G. Branton, Ouafa Zghidi-Abouzid, Eric A. Cohen, Benjamin B. Gelman, Jerome Estaquier, Linglong Kong, Christopher Power
Publikováno v:
Viruses, Vol 15, Iss 2, p 316 (2023)
HIV-encoded DNA, RNA and proteins persist in the brain despite effective antiretroviral therapy (ART), with undetectable plasma and cerebrospinal fluid viral RNA levels, often in association with neurocognitive impairments. Although the determinants
Externí odkaz:
https://doaj.org/article/a39154ea0d0941cc93f86f5fa0cc9abb
Autor:
Lijia Jia, Zhen Chen, Yecheng Zhang, Li Ma, Liying Wang, Xiao Hu, Haizhou Liu, Jianjun Chen, Di Liu, Wuxiang Guan
Publikováno v:
Frontiers in Microbiology, Vol 12 (2021)
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is currently the most important emerging pathogen worldwide, but its early transcriptional dynamics and host immune response remain unclear. Herein, the expression profiles of viral interac
Externí odkaz:
https://doaj.org/article/57e3f3e4c4054aa9bd4e5c31dec4aa4b
Akademický článek
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Autor:
Yumna Moosa, Ramla F. Tanko, Veron Ramsuran, Ravesh Singh, Mashudu Madzivhandila, Nonhlanhla Yende-Zuma, Melissa-Rose Abrahams, Philippe Selhorst, Kamini Gounder, Penny L. Moore, Carolyn Williamson, Salim S. Abdool Karim, Nigel J. Garrett, Wendy A. Burgers
Publikováno v:
BMC Infectious Diseases, Vol 18, Iss 1, Pp 1-7 (2018)
Abstract Background The majority of people living with HIV require antiretroviral therapy (ART) for controlling viral replication, however there are rare HIV controllers who spontaneously and durably control HIV in the absence of treatment. Understan
Externí odkaz:
https://doaj.org/article/2629c9832d204b99a6361f0db86fb9ed