Výsledky vyhledávání - "host restriction"

Akademický článek

Interactions between HIV proteins and host restriction factors: implications for potential therapeutic intervention in HIV infection

Autor: Farooq Rashid, Silvere D. Zaongo, Hifza Iqbal, Vijay Harypursat, Fangzhou Song, Yaokai Chen

Publikováno v: Frontiers in Immunology, Vol 15 (2024)

Different host proteins target different HIV proteins and antagonize their functions, depending on the stage of the HIV life cycle and the stage of infection. Concurrently, HIV proteins also target and antagonize various different host proteins to fa

Externí odkaz: https://doaj.org/article/a4cad7f2411d42699f7c444da7b5dd6f

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Akademický článek

A novel host restriction factor MRPS6 mediates the inhibition of PDCoV infection in HIEC-6 cells

Autor: Yuhang Jiang, Guoqing Zhang, Letian Li, Jing Chen, Pengfei Hao, Zihan Gao, Jiayi Hao, Zhiqiang Xu, Maopeng Wang, Chang Li, Ningyi Jin

Publikováno v: Frontiers in Immunology, Vol 15 (2024)

IntroductionPorcine deltacoronavirus (PDCoV) is a zoonotic pathogen with a global distribution, capable of infecting both pigs and humans. To mitigate the risk of cross-species transmission and potential outbreaks, it is crucial to characterize novel

Externí odkaz: https://doaj.org/article/a458c8bb3e764de7b52849565dc00076

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Akademický článek

Impaired influenza A virus replication by the host restriction factor SAMHD1 which inhibited by PA-mediated dephosphorylation of the host transcription factor IRF3

Autor: Zhilei Zhao, Shuyi Han, Qingxun Zhang, Ye Wang, Kening Yue, Salbia Abbas, Hongxuan He

Publikováno v: Virology Journal, Vol 21, Iss 1, Pp 1-15 (2024)

Abstract Background Influenza A virus (IAV) can cause severe and life-threatening illness in humans and animals. Therefore, it is important to search for host antiviral proteins and elucidate their antiviral mechanisms for the development of potentia

Externí odkaz: https://doaj.org/article/3a71658cc77d4a32a771cb417021cc06

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Akademický článek

Intracellular Host Restriction of Hepatitis B Virus Replication

Autor: Prakriti Sinha, Chloe L. Thio, Ashwin Balagopal

Publikováno v: Viruses, Vol 16, Iss 5, p 764 (2024)

The hepatitis B virus (HBV) infects hepatocytes and hijacks host cellular mechanisms for its replication. Host proteins can be frontline effectors of the cell’s defense and restrict viral replication by impeding multiple steps during its intracellu

Externí odkaz: https://doaj.org/article/249a04dd8e184ee8acb66971ab7e0917

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Akademický článek

The Susceptibility of Chickens to Zika Virus: A Comprehensive Study on Age-Dependent Infection Dynamics and Host Responses

Autor: Ruth H. Nissly, Levina Lim, Margo R. Keller, Ian M. Bird, Gitanjali Bhushan, Sougat Misra, Shubhada K. Chothe, Miranda C. Sill, Nagaram Vinod Kumar, A. V. N. Sivakumar, B. Rambabu Naik, Bhushan M. Jayarao, Suresh V. Kuchipudi

Publikováno v: Viruses, Vol 16, Iss 4, p 569 (2024)

Zika virus (ZIKV) remains a public health concern, with epidemics in endemic regions and sporadic outbreaks in new areas posing significant threats. Several mosquito-borne flaviviruses that can cause human illness, including West Nile, Usutu, and St.

Externí odkaz: https://doaj.org/article/72e55b32eef74d47995e6f34d12e0f03

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Akademický článek

Virus Research

Externí odkaz: https://doaj.org/toc/1872-7492

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Akademický článek

Hepatitis B Virus X Protein Inhibits the Expression of Barrier To Autointegration factor1 via Upregulating miR-203 Expression in Hepatic Cells

Autor: Amit Kumar Mishra, Md Musa Hossain, Teja Naveen Sata, Ajay K. Yadav, Shahidullah Zadran, Amrendra Kumar Sah, Baibaswata Nayak, Shalimar, Senthil Kumar Venugopal

Publikováno v: Microbiology Spectrum, Vol 11, Iss 1 (2023)

ABSTRACT Hepatitis B virus (HBV) infection targets host restriction factors that inhibit its replication and survival. Previous studies have shown that barriers to autointegration factor1 (BANF1) inhibited the replication of herpes simplex virus and

Externí odkaz: https://doaj.org/article/4fecb3359e584249b802786a2072d53e

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