Understanding the nuances of intercellular communication with sensitive mass spectrometric approaches

Autor: Bauza Martinez, Julia

In this thesis, I applied high-sensitivity mass spectrometry (MS) approaches to characterize extracellular vesicles (EVs) and peptide hormones, two key systems for cell-to-cell communication. With thoughtful sample pretreatment and LC-MS/MS strategie

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od_______101::c29f78c93c223130db03940dd388aea9
https://dspace.library.uu.nl/handle/1874/423735

Hormonal modifiers of breast and ovarian cancer risk in BRCA1/2 mutation carriers

Women who carry a pathogenic variant (mutation) in the BRCA1 or BRCA2 genes have a high lifetime risk of breast and ovarian cancer. The high lifetime breast and ovarian cancer risks among BRCA1 and BRCA2 mutation carriers shows a wide variation. Know

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______4612::9bf051901e1a6125af6f05ef20f616be
https://research.vu.nl/en/publications/32faae24-1a32-44cd-acfe-4ed808333951

The psychobiology of early fatherhood: exploring the neural and hormonal aspects

Fathers’ involvement and parenting behaviors are associated with positive child development, attachment security, and well-being of the child. Interestingly, only little research focused on the onset of these parental behaviors and its possible und

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______4612::1e7ca256cce8b17fb9ac84418ba11e45
https://research.vu.nl/en/publications/67c2c2d2-848a-4a09-8c9c-be66a56e7f7e

Effect-Based Analysis of Endocrine Disrupting Chemical Mixtures in Breast Milk and Possible Health Consequences for Human Infants

Autor: Collet, Bérénice Constance

Publikováno v: Collet, B C 2021, ' Effect-Based Analysis of Endocrine Disrupting Chemical Mixtures in Breast Milk and Possible Health Consequences for Human Infants. ', PhD, Vrije Universiteit Amsterdam, s.l. .

The research described in this thesis investigated the amount and potential effects of EDCs present in human milk using samples derived from the Norwegian HUMIS cohort. This work focused on three main actors of the endocrine system, the estrogens, an

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::cd5e80a1dacc486452e9ebcb832c87d6
https://hdl.handle.net/1871.1/a9592017-ec7b-4bd1-bc6f-f00a4af7b07d

Female reproductive health: Species and ligand-specific endometrial differences to hormones and aryl hydrocarbon receptor activation

Endometrial diseases affect up to approximately 10% of women in their reproductive age. Yet, current testing strategies in chemical risk assessment do not adequately address endometrial health, partly because good (animal-free and human relevant) mod

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dris___00893::54715f487e05c1e195248ffdbea0a034
https://hdl.handle.net/1874/391078