Zobrazeno 1 - 10
of 15 829
pro vyhledávání: '"homology modeling"'
Autor:
Ahmad Nasir, Khan Khalid, Khan Sher Wali, Ur Rashid Haroon, Irum, Zahoor Muhammad, Umar Muhammad Naveed, Ullah Riaz, Ali Essam A.
Publikováno v:
Open Chemistry, Vol 22, Iss 1, Pp 1868-78 (2024)
Externí odkaz:
https://doaj.org/article/9b2d005c98024b4490489b48ca36abfc
Publikováno v:
Journal of Taibah University Medical Sciences, Vol 19, Iss 2, Pp 233-247 (2024)
الملخص: أهداف البحث: تم تصميم هذا العمل لدراسة 4،2-مزدوج الاستبدال 6-فلوروكينولين كعوامل مضادة للبلازموديات تستخدم في تقنيات السيليكو بهد
Externí odkaz:
https://doaj.org/article/bdb7ad2dbce14627931d457b99e4a46f
Autor:
Nouhaila Ait Lahcen, Wissal Liman, Mehdi Oubahmane, Ismail Hdoufane, Youssef Habibi, Ashwag S. Alanazi, Mohammed M. Alanazi, Christelle Delaite, Mohamed Maatallah, Driss Cherqaoui
Publikováno v:
Arabian Journal of Chemistry, Vol 17, Iss 9, Pp 105870- (2024)
Ebola virus disease is a deadly pathogenic disease with a fatality rate of 25–90 % as recorded in previous outbreaks. The Ebola Virus glycoprotein (EBOV-GP) plays a crucial role in the entry of viruses into human cells, making it an interesting tar
Externí odkaz:
https://doaj.org/article/f25c10681696496bb24cbf05acc150de
Autor:
Tianjiao Mao, Bo Chen, Wei Wei, Guiping Chen, Zhuoyuan Liu, Lihong Wu, Xiaomeng Li, Janak L. Pathak, Jiang Li
Publikováno v:
Heliyon, Vol 10, Iss 13, Pp e33860- (2024)
Primary Sjögren's Syndrome (pSS) is a systemic autoimmune disease that leads to reduced saliva production, primarily affecting women due to estrogen deficiency. The estrogen receptor α (ERα) plays a crucial role in mediating the expression of the
Externí odkaz:
https://doaj.org/article/ef49a9c2401944c89f2b11b4e6e5b8b5
Publikováno v:
Animal Diseases, Vol 4, Iss 1, Pp 1-11 (2024)
Abstract This is the first report on the screening, expression, and recognition mechanism analysis of single-chain fragment variable (scFv) against phenylethanolamine A (PEAA), a newly emerged β-adrenergic agonist illegally used as a feed additive f
Externí odkaz:
https://doaj.org/article/25dc704742d74b6fbc1d9648522dc036
Autor:
Aisha Naeem, Nighat Noureen, Shaikha Khalid Al-Naemi, Jawaher Ahmed Al-Emadi, Muhammad Jawad Khan
Publikováno v:
BMC Chemistry, Vol 18, Iss 1, Pp 1-16 (2024)
Abstract Anti-cancer peptides (ACPs) are short peptides known for their ability to inhibit tumor cell proliferation, migration, and the formation of tumor blood vessels. In this study, we designed ACPs to target receptors often overexpressed in cance
Externí odkaz:
https://doaj.org/article/cdf22ef39a754eaca80dfbc056f90951
Autor:
Rajasekaran Subbarayan, Dhasarathdev Srinivasan, Salman Sadullah Usmani, Dinesh Murugan Girija, Shoeb Ikhlas, Nityanand Srivastav, Ranjith Balakrishnan, Rupendra Shrestha, Ankush Chauhan
Publikováno v:
Platelets, Vol 35, Iss 1 (2024)
The purpose of this study is to investigate the molecular interactions and potential therapeutic uses of Eltrombopag (EPAG), a small molecule that activates the cMPL receptor. EPAG has been found to be effective in increasing platelet levels and alle
Externí odkaz:
https://doaj.org/article/71894afd5bf346fabde0e21c91872dce
Autor:
Geraldine B. Dayrit, Normela Patricia F. Burigsay, Emmanuel M. Vera Cruz, Mudjekeewis D. Santos
Publikováno v:
Heliyon, Vol 10, Iss 12, Pp e32748- (2024)
The molecular chaperone heat shock proteins 70 (Hsp70) play a pivotal role in preserving cellular integrity and managing stress. This study extensively examined two Hsp70 proteins, On-Hsp70cBi, inducible, and On-Hsp70cBc, constitutively expressed, in
Externí odkaz:
https://doaj.org/article/79c87587bc544e108738fcf425851e27
Autor:
Saudatu Chinade Jáafaru, Adamu Uzairu, Muhammed Sani Sallau, George Iloegbulam Ndukwe, Muhammad Tukur Ibrahim, Kamal Tabti, Pallavi Kandpal, Vimal Kumar
Publikováno v:
Scientific African, Vol 24, Iss , Pp e02169- (2024)
Schistosomiasis is a chronic parasitic disease with significant public health challenges due to the limited number of treatment options and increasing levels of drug resistance against the only available drug, Praziquantel (PZQ). Consequently, there
Externí odkaz:
https://doaj.org/article/eff6acc3d3fe4753a817d37b6eaf62bd