Zobrazeno 1 - 10
of 68
pro vyhledávání: '"homing endonuclease genes"'
Autor:
Burt, Austin
Publikováno v:
Proceedings: Biological Sciences, 2003 May 01. 270(1518), 921-928.
Externí odkaz:
https://www.jstor.org/stable/3558626
Publikováno v:
S80
S66
S66
Despite impressive progress, malaria continues to impose a substantial burden of mortality and morbidity, particularly in sub-Saharan Africa, and new tools will be needed to achieve elimination. Gene drive is a natural process by which some genes are
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf3e796837d3eb0317d5588c3e79f81d
https://doi.org/10.1080/23299460.2017.1419410
https://doi.org/10.1080/23299460.2017.1419410
Publikováno v:
Malaria Journal, Vol 16, Iss 1, Pp 1-14 (2017)
Malaria Journal
Malaria Journal
Background The introduction of new malaria control interventions has often led to the evolution of resistance, both of the parasite to new drugs and of the mosquito vector to new insecticides, compromising the efficacy of the interventions. Recent pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8915a17d06669174ec123b719e1c9ad7
http://link.springer.com/article/10.1186/s12936-017-1932-7
http://link.springer.com/article/10.1186/s12936-017-1932-7
Autor:
Andrew Hammond, Roberto Galizi
Self-propagating gene drive technologies have a number of desirable characteristics that warrant their development for the control of insect pest and vector populations, such as the malaria-transmitting mosquitoes. Theoretically easy to deploy and se
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5416b74bcdd1f84e5cc3f9329e4d842e
Akademický článek
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Publikováno v:
Ecology and Evolution
Genetically engineered (GE) insects have the potential to radically change pest management worldwide. With recent approvals of GE insect releases, there is a need for a synthesized framework to evaluate their potential ecological and evolutionary eff
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce86bf4f39c2e65f3b80bf26ee731a0c
http://europepmc.org/articles/PMC3810890
http://europepmc.org/articles/PMC3810890
Publikováno v:
E264
E255
E255
The renewed effort to eliminate malaria and permanently remove its tremendous burden highlights questions of what combination of tools would be sufficient in various settings and what new tools need to be developed. Gene drive mosquitoes constitute a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd1a248d4bf82efee694d7cc78bf7777
https://doi.org/10.1073/pnas.1611064114
https://doi.org/10.1073/pnas.1611064114
Autor:
Roberto Galizi, Andrew Hammond, Alekos Simoni, Nikolai Windbichler, Austin Burt, Steven Russell, Eric Marois, Matthew Gribble, Dean A. Baker, Kyros Kyrou, Andrea Crisanti, Dimitris Katsanos, Tony Nolan, Carla Siniscalchi
Publikováno v:
Nature biotechnology
Gene-drive systems that enable super-Mendelian inheritance of a transgene have the potential to modify insect populations over a timeframe of a few years [AU please provide a real estimate, this seems vague]. We describe CRISPR-Cas9 endonuclease cons
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a618727d0ad73e9596b88f7f0dd949a7
Publikováno v:
Fungal Genetics and Biology 49 (2012) 3
Fungal Genetics and Biology, 49(3), 250-261
Fungal Genetics and Biology, 49(3), 250-261
The mobile elements termed inteins have a sporadic distribution in microorganisms. It is unclear how these elements are maintained. Inteins are intervening protein sequences that autocatalytically excise themselves from a precursor. Excision is a pos
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f28d4d282badd3dc9ed7aa6724093bea
https://doi.org/10.1016/j.fgb.2012.01.001
https://doi.org/10.1016/j.fgb.2012.01.001
Akademický článek
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