Zobrazeno 1 - 10
of 368
pro vyhledávání: '"homeostatic synaptic plasticity"'
Autor:
Maximilian Lenz, Paul Turko, Pia Kruse, Amelie Eichler, Zhuo Angel Chen, Juri Rappsilber, Imre Vida, Andreas Vlachos
Publikováno v:
Molecular Brain, Vol 17, Iss 1, Pp 1-9 (2024)
Abstract Understanding the mechanisms of synaptic plasticity is crucial for elucidating how the brain adapts to internal and external stimuli. A key objective of plasticity is maintaining physiological activity states during perturbations by adjustin
Externí odkaz:
https://doaj.org/article/27934baf442b403783f2185ea8c3d639
Autor:
Jonathan Mayzel, Elad Schneidman
Publikováno v:
eLife, Vol 13 (2024)
Studying and understanding the code of large neural populations hinge on accurate statistical models of population activity. A novel class of models, based on learning to weigh sparse nonlinear Random Projections (RP) of the population, has demonstra
Externí odkaz:
https://doaj.org/article/8a0d7609e9e24531a51e006b3466e661
Akademický článek
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Autor:
Hey-Kyoung Lee
Publikováno v:
Frontiers in Synaptic Neuroscience, Vol 14 (2023)
Sensory loss leads to widespread adaptation of neural circuits to mediate cross-modal plasticity, which allows the organism to better utilize the remaining senses to guide behavior. While cross-modal interactions are often thought to engage multisens
Externí odkaz:
https://doaj.org/article/7bb7661fd964446ab7afe1b71877fb52
Autor:
Gai-Linn Kay Besing, Emily Kate St. John, Cobie Victoria Potesta, Martin J. Gallagher, Chengwen Zhou
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 16 (2022)
During non-rapid eye movement (NREM) sleep, cortical neuron activity alternates between a depolarized (firing, up-state) and a hyperpolarized state (down-state) coinciding with delta electroencephalogram (EEG) slow-wave oscillation (SWO, 0. 5–4 Hz)
Externí odkaz:
https://doaj.org/article/c3a3cd89399f454f9c730d4bc8053b77
Autor:
Isak Martinsson, Luis Quintino, Megg G. Garcia, Sabine C. Konings, Laura Torres-Garcia, Alexander Svanbergsson, Oliver Stange, Rebecca England, Tomas Deierborg, Jia-Yi Li, Cecilia Lundberg, Gunnar K. Gouras
Publikováno v:
Frontiers in Aging Neuroscience, Vol 14 (2022)
Alzheimer’s disease (AD) is increasingly seen as a disease of synapses and diverse evidence has implicated the amyloid-β peptide (Aβ) in synapse damage. The molecular and cellular mechanism(s) by which Aβ and/or its precursor protein, the amyloi
Externí odkaz:
https://doaj.org/article/ff57882822e84937998f1dfb99ae5e93
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 16 (2022)
Externí odkaz:
https://doaj.org/article/de069d648070475e82136f93e2fc8431
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 16 (2022)
Prolonged changes in neural activity trigger homeostatic synaptic plasticity (HSP) allowing neuronal networks to operate within functional ranges. Cell-wide or input-specific adaptations can be induced by pharmacological or genetic manipulations of a
Externí odkaz:
https://doaj.org/article/70d446e3047e4b75a7a99d022fe6960e
Publikováno v:
Frontiers in Systems Neuroscience, Vol 15 (2021)
The human brain constitutes one of the most advanced networks produced by nature, consisting of billions of neurons communicating with each other. However, this communication is not in real-time, with different communication or time-delays occurring
Externí odkaz:
https://doaj.org/article/f007df6f14db4f9eaa438987ee668c0a
Publikováno v:
Bioelectronic Medicine, Vol 5, Iss 1, Pp 1-9 (2019)
Abstract Hyperexcitability of the neural network often occurs after brain injuries or degeneration and is a key pathophysiological feature in certain neurological diseases such as epilepsy, neuropathic pain, and tinnitus. Although the standard approa
Externí odkaz:
https://doaj.org/article/0010de5172194ac1b54d0aac5b1c9817