Zobrazeno 1 - 10
of 263
pro vyhledávání: '"homeostasi"'
Publikováno v:
Immunity. 55:1981-1992
Compelling experimental evidence links immunity and metabolism. In this perspective, we propose forkhead-box-P3 (FoxP3)+CD4+CD25+ regulatory T (Treg) cells as key metabolic sensors controlling the immunological state in response to their intrinsic ca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b5c08a9383060697a4d8583dd35c1339
https://doi.org/10.1016/j.immuni.2022.10.006
https://doi.org/10.1016/j.immuni.2022.10.006
Autor:
Maria Josè Sisalli, Salvatore Della Notte, Agnese Secondo, Carmelo Ventra, Lucio Annunziato, Antonella Scorziello
Publikováno v:
Cells; Volume 11; Issue 18; Pages: 2909
The altered crosstalk between mitochondrial dysfunction, intracellular Ca2+ homeostasis, and oxidative stress has a central role in the dopaminergic neurodegeneration. In the present study, we investigated the hypothesis that pharmacological strategi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c61cfa4526f69aec3162fafbec56b9b
https://pubmed.ncbi.nlm.nih.gov/36139485
https://pubmed.ncbi.nlm.nih.gov/36139485
Autor:
DAddio, Francesca, Maestroni, Anna, Assi, Emma, Ben Nasr, Moufida, Amabile, Giovanni, Usuelli, Vera, Loretelli, Cristian, Bertuzzi, Federico, Antonioli, Barbara, Cardarelli, Francesco, El Essawy, Basset, Solini, Anna, Gerling, Ivan C., Bianchi, Cristina, Becchi, Gabriella, Mazzucchelli, Serena, Corradi, Domenico, Fadini, Gian Paolo, Foschi, Diego, Markmann, James F., Orsi, Emanuela, Skrha, Jan, Camboni, Maria Gabriella, Abdi, Reza, Shapiro, A. M. James, Folli, Franco, Ludvigsson, Johnny, Del Prato, Stefano, Zuccotti, Gianvincenzo, Fiorina, Paolo
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-14 (2022)
In this new study the Authors demonstrated that the IGFBP3/TMEM219 pathway is a physiological regulator of pancreatic beta cell homeostasis and it is dysregulated in diabetes. IGFBP3/TMEM219 targeting may therefore serve as a therapeutic option in di
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::16a1637726e38a17c6ee19d54febc12a
https://doaj.org/article/691fd79ad7294c7890d97254a673270c
https://doaj.org/article/691fd79ad7294c7890d97254a673270c
Autor:
Debora Bencivenga, Francesco Arcadio, Angelantonio Piccirillo, Marco Annunziata, Fulvio Della Ragione, Nunzio Cennamo, Adriana Borriello, Luigi Zeni, Luigi Guida
Numerous pieces of evidence demonstrate that oxidative stress impairs biological functions, speeds up aging, and has a role in a variety of human diseases, including systemic and oral inflammatory disorders, and even cancer. Therefore, technologies p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07f4c9b1bd12915884662486fca47355
https://hdl.handle.net/11591/491636
https://hdl.handle.net/11591/491636
Autor:
Sara Baldassano, Anna Alioto, Alessandra Amato, Carlo Rossi, Giulia Messina, Maria Roberta Bruno, Roberta Stallone, Patrizia Proia
Over the past two years, the world’s population has been tested by the COVID-19 health emergency. This has changed population habits worldwide by encouraging a sedentary lifestyle and overnutrition. Isolation and reduction of social life, for most
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af9b38c332d5584c3e39aaad1f9ba1e6
https://hdl.handle.net/10447/579496
https://hdl.handle.net/10447/579496
Publikováno v:
Biochemistry (Moscow). 86:1526-1539
The telomere theory tries to explain cellular mechanisms of aging as mainly caused by telomere shortening at each duplication. The subtelomere–telomere theory overcomes various shortcomings of telomere theory by highlighting the essential role of s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::778afdd1947c6052ff1da38b5ff9ec49
https://doi.org/10.1134/s0006297921120026
https://doi.org/10.1134/s0006297921120026
Publikováno v:
Plant Physiology and Biochemistry. 169:190-202
Low temperatures (0–10 °C) represent a major physiological stress for plants, negatively affecting both their growth rates and overall growth. Cold stress may induce a wide range of negative physiological effects, from oxidative stress to photosyn
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53a15e3be0e560d4f4f378076bb17d22
https://doi.org/10.1016/j.plaphy.2021.11.017
https://doi.org/10.1016/j.plaphy.2021.11.017
Publikováno v:
Pflugers Archiv
Pflugers Arch
Pflugers Arch
The capacity of astrocytes to adapt their biochemical and functional features upon physiological and pathological stimuli is a fundamental property at the basis of their ability to regulate the homeostasis of the central nervous system (CNS). It is w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c2fa1944cb8357d32193c54c2ddfa842
http://europepmc.org/articles/PMC8766406
http://europepmc.org/articles/PMC8766406
Autor:
Alberto Fucarino, Stefano Burgio, Letizia Paladino, Celeste Caruso Bavisotto, Alessandro Pitruzzella, Fabio Bucchieri, Francesco Cappello
In this paper, we want to refute the notion that the microbiota should be considered an organ, given that an organ comprises tissue of similar or different embryological origin, while the microbiota is a pool of different microbial species originatin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f77077e114030d26d4e30e3ef6e65c13
https://hdl.handle.net/10447/573807
https://hdl.handle.net/10447/573807
Autor:
MARIA PAOLA TURINA
Publikováno v:
Frontiers in Molecular Biosciences. 9
F-type ATP synthases are transmembrane enzymes, which play a central role in the metabolism of all aerobic and photosynthetic cells and organisms, being the major source of their ATP synthesis. Catalysis occurs via a rotary mechanism, in which the fr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::91637e044545b9348ee8b7f06b8182f1
https://doi.org/10.3389/fmolb.2022.1023031
https://doi.org/10.3389/fmolb.2022.1023031