Zobrazeno 1 - 10
of 288
pro vyhledávání: '"hnsc"'
Autor:
Xu Miao, Shi Run, Yang Jie, Chen Heng, Liu Shihua, Yu Shupei, Li Sasa, He Wenqiang, Sy Man-Sun, Lu Mingjian, Zhang Huixia, Li Chaoyang
Publikováno v:
Acta Biochimica et Biophysica Sinica, Vol 56, Pp 1833-1847 (2024)
There are three isoforms of human collagen prolyl 4-hydroxylases (C-P4Hs), each of which has been reported to play an important role in regulating the progression of a variety of human cancers. By analyzing TGCA datasets on human head and neck squamo
Externí odkaz:
https://doaj.org/article/a4bc8ca054934b22b48b170907f8ec32
Autor:
Xiaoxia Zeng, Dunhui Yang, Jin Zhang, Kang Li, Xijia Wang, Fang Ma, Xianqin Liao, Zhen Wang, Xianhai Zeng, Peng Zhang
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Head and neck squamous carcinoma (HNSC), characterized by a high degree of malignancy, develops in close association with the tumor immune microenvironment (TIME). Therefore, identifying effective targets related to HNSC and TIME is of paramount impo
Externí odkaz:
https://doaj.org/article/2f11de91f93a44f0823782191f724b9f
Publikováno v:
Discover Oncology, Vol 15, Iss 1, Pp 1-16 (2024)
Abstract Objective Angiogenesis-associated genes (AAGs) play a critical role in cancer patient survival. However, there are insufficient reports on the prognostic value of AAGs in head and neck squamous cell carcinoma (HNSC). Therefore, this study ai
Externí odkaz:
https://doaj.org/article/2d815a03752f46c08b62ed94352575d3
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-14 (2024)
Abstract Prolyl 4-hydroxylases (P4Hs) are a family of key modifying enzymes in collagen synthesis. P4Hs have been confirmed to be closely associated with tumor occurrence and development. However, the expression of P4Hs in head and neck cancer (HNSC)
Externí odkaz:
https://doaj.org/article/591b3b14b9a34366b363a8212a90b70b
Autor:
Juanli Xing, Yanan Gu, Yichen Song, Qi Liu, Qian Chen, Peng Han, Zhen Shen, Huajing Li, Shaoqiang Zhang, Yanxia Bai, Junchi Ma, Fang Sui
Publikováno v:
BMC Cancer, Vol 23, Iss 1, Pp 1-14 (2023)
Abstract Head and neck squamous carcinoma (HNSC) poses a significant public health challenge due to its substantial morbidity. Nevertheless, despite advances in current treatments, the prognosis for HNSC remains unsatisfactory. To address this, singl
Externí odkaz:
https://doaj.org/article/8ddc0839e2bd499a8bca590ce029f47a
Publikováno v:
Discover Oncology, Vol 14, Iss 1, Pp 1-20 (2023)
Abstract Objective To identify the pivotal genes, specifically the STTK genes, that govern the sensitivity of tumor cells to T cell-mediated killing in Head and Neck Squamous Cell Carcinoma (HNSC). Methods The differentially expressed genes (DEGs) in
Externí odkaz:
https://doaj.org/article/e11694020a604fd68954fec50c8abf1d
Autor:
Juan Hu, Jing Yan, Yijie Chen, Xiaohui Li, Liu Yang, Haiyu Di, Huihui Zhang, Yewen Shi, Junjie Zhao, Yanxia Shi, Yinglong Xu, Xiaoyong Ren, Zhenghui Wang
Publikováno v:
BMC Cancer, Vol 23, Iss 1, Pp 1-12 (2023)
Abstract Background The establishment of sister chromatid cohesion N-acetyltransferase 2 (ESCO2) is involved in the development of multiple malignancies. However, its role in hypopharyngeal carcinoma (HPC) progression remains uncharacterized. Methods
Externí odkaz:
https://doaj.org/article/809a1590f40a4cd7bfd50a402d44d035
Publikováno v:
PeerJ, Vol 12, p e17028 (2024)
Background Autophagy, a crucial cellular mechanism, facilitates the degradation and removal of misfolded proteins and impaired organelles. Recent research has increasingly highlighted the intimate connection between autophagy and heat shock proteins
Externí odkaz:
https://doaj.org/article/7882390d815a45e09b141f58f2f8bd6a
Autor:
Huadong Wu, Zhenzhen Fu, Hong Li, Feifei Fang, Bin He, Yujie Ye, Heyong Wu, Dong Xu, Haoran Zheng, Qiang Zhang
Publikováno v:
Frontiers in Immunology, Vol 14 (2024)
ObjectiveAs a pseudokinase, Tribbles Pseudokinase 3 (TRIB3) is implicated in a wide array of biological processes, including cell signal transduction, metabolic regulation, stress responses, and immune regulation. While its significant role in the im
Externí odkaz:
https://doaj.org/article/7f24044aadce41cb8d6a688642a824c3
Autor:
Fangyu Chai, Jingfang Zhang, Tao Fu, Peng Jiang, Yichuan Huang, Lin Wang, Shu Yan, Xudong Yan, Longgang Yu, Zhen Xu, Ruohuang Wang, Bingqing Xu, Xiaoyun Du, Yan Jiang, Jisheng Zhang
Publikováno v:
Channels, Vol 17, Iss 1 (2023)
ABSTRACTSLC2A3 is an important member of the glucose transporter superfamily. It has been recently suggested that upregulation of SLC2A3 is associated with poor survival and acts as a prognostic marker in a variety of tumors. Unfortunately, the progn
Externí odkaz:
https://doaj.org/article/c8432719d52b4d1ba2d1d0950bfd621f