Zobrazeno 1 - 10
of 321
pro vyhledávání: '"hnRNPA2B1"'
Publikováno v:
陆军军医大学学报, Vol 46, Iss 20, Pp 2284-2290 (2024)
Objective To investigate the molecular mechanism of translocation of heterogeneous nuclear ribonucleoprotein A2B1 (hnRNPA2B1) to the cytoplasm after glucose starvation and the effects of increased cytoplasmic translocation of hnRNPA2B1 on the surviva
Externí odkaz:
https://doaj.org/article/ba94a629420b47e7aa6317dad1c36171
Publikováno v:
Current Issues in Molecular Biology, Vol 46, Iss 9, Pp 9624-9638 (2024)
Recent studies have confirmed that melatonin and N6-methyladenosine (m6A) modification can influence bone cell differentiation and bone formation. Melatonin can also regulate a variety of biological processes through m6A modification. Heterogeneous n
Externí odkaz:
https://doaj.org/article/c91d7c3783fe41669d94ea27e0a44b66
Autor:
Jiayao Wang, Jiehao Zhang, Hao Liu, Lingnan Meng, Xianchun Gao, Yihan Zhao, Chen Wang, Xiaoliang Gao, Ahui Fan, Tianyu Cao, Daiming Fan, Xiaodi Zhao, Yuanyuan Lu
Publikováno v:
Cancer Communications, Vol 44, Iss 4, Pp 469-490 (2024)
Abstract Background Chemoresistance is a major cause of treatment failure in gastric cancer (GC). Heterogeneous nuclear ribonucleoprotein A2B1 (hnRNPA2B1) is an N6‐methyladenosine (m6A)‐binding protein involved in a variety of cancers. However, w
Externí odkaz:
https://doaj.org/article/eb8215ba60954ea38b26a561ed35a0e8
Publikováno v:
Advanced Science, Vol 11, Iss 30, Pp n/a-n/a (2024)
Abstract Helicobacter pylori (H. pylori) infection is the primary risk factor for the pathogenesis of gastric cancer (GC). N6‐methyladenosine (m6A) plays pivotal roles in mRNA metabolism and hnRNPA2B1 as an m6A reader is shown to exert m6A‐depend
Externí odkaz:
https://doaj.org/article/85559fc5142348a8920c6db8b5af7ebb
Publikováno v:
Journal of Translational Medicine, Vol 21, Iss 1, Pp 1-16 (2023)
Abstract Background N6-methyladenosine (m6A) is the most prevalent RNA modification. Although hnRNPA2B1, as a reader of m6A modification, has been reported to promote tumorigenesis in a few types of tumors, its role in hepatocellular carcinoma (HCC)
Externí odkaz:
https://doaj.org/article/bbf0ff64e7e9448bb1da64db08ff4a54
Publikováno v:
Journal of Nanobiotechnology, Vol 21, Iss 1, Pp 1-14 (2023)
Abstract Background Despite being a common malignant tumor, the molecular mechanism underlying the initiation and progression of triple-negative breast cancers (TNBCs) remain unclear. Tumor-associated macrophages (TAMs) are often polarized into a pro
Externí odkaz:
https://doaj.org/article/9528b4aa8cdd469bafc3a72ba41d4b60
Autor:
Ke Li, Quan Gong, Xu-Dong Xiang, Gang Guo, Jia Liu, Li Zhao, Jun Li, Nan Chen, Heng Li, Li-Juan Zhang, Chun-Yan Zhou, Zhi-Yong Wang, Li Zhuang
Publikováno v:
Journal of Translational Medicine, Vol 21, Iss 1, Pp 1-14 (2023)
Abstract Background Accumulating data indicate that N6-methyladenosine (m6A) RNA methylation and lncRNA deregulation act crucial roles in cancer progression. Heterogeneous nuclear ribonucleoprotein A2B1 (HNRNPA2B1) as an m6A “reader” has been rep
Externí odkaz:
https://doaj.org/article/4bfad2646fde4bd7a8eaf26b1e42b5c8
Publikováno v:
Virus Research, Vol 336, Iss , Pp 199224- (2023)
Objective: To investigate the effect of heterogeneous nuclear ribonucleoprotein A2B1 (HNRNPA2B1) on the replication of enterovirus 71 (EV-71) in SK-N-SH cells. Methods: The mRNA and protein expression of HNRNPA2B1 in SK-N-SH cells were detected by re
Externí odkaz:
https://doaj.org/article/9554ec2ea88447d8966f6487d1011c29
Autor:
Qiulei Wu, Guoqing Li, Lanqing Gong, Jing Cai, Le Chen, Xiaohan Xu, Xiaoli Liu, Jing Zhao, Ya Zeng, Rui Gao, Lili Yu, Zehua Wang
Publikováno v:
Cancer Medicine, Vol 12, Iss 4, Pp 5055-5070 (2023)
Abstract Background microRNAs (miRNAs) and N6‐methyladenosine (m6A) play important roles in ovarian cancer (OvCa). However, the mechanisms by which miRNAs regulate m6A in OvCa have not been elucidated so far. Methods To screen m6A‐related miRNAs,
Externí odkaz:
https://doaj.org/article/5c14db0b0bdc4b19ab820275feed33dd
Publikováno v:
Journal of Ovarian Research, Vol 16, Iss 1, Pp 1-13 (2023)
Abstract Background Ovarian cancer (OC) is one of the commonest and deadliest diseases that threaten the health of women worldwide. It is essential to find out its pathogenic mechanisms and therapeutic targets for OC patients. Although NUF2 (Ndc80 ki
Externí odkaz:
https://doaj.org/article/e1d2051f44814d50a4d003eb5141c8cc