Zobrazeno 1 - 10
of 4 678
pro vyhledávání: '"hla class i"'
Publikováno v:
JAAD Case Reports, Vol 51, Iss , Pp 22-25 (2024)
Externí odkaz:
https://doaj.org/article/3146f709597e495f9960a0912d8774f4
Autor:
Duane C. Harris, Apoorv Shanker, Makaela M. Montoya, Trent R. Llewellyn, Anna R. Matuszak, Aditi Lohar, Jessica Z. Kubicek-Sutherland, Ying Wai Li, Kristen Wilding, Ben Mcmahon, Sandrasegaram Gnanakaran, Ruy M. Ribeiro, Alan S. Perelson, Carmen Molina-París
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Vaccines have historically played a pivotal role in controlling epidemics. Effective vaccines for viruses causing significant human disease, e.g., Ebola, Lassa fever, or Crimean Congo hemorrhagic fever virus, would be invaluable to public health stra
Externí odkaz:
https://doaj.org/article/ffe0469cf0d941c6bf7e57eae0e04be7
Publikováno v:
Emerging Microbes and Infections, Vol 13, Iss 1 (2024)
ABSTRACTCytotoxic T lymphocytes are key for controlling viral infection. Unravelling CD8+ T cell-mediated immunity to distinct influenza virus strains and subtypes across prominent HLA types is relevant for combating seasonal infections and emerging
Externí odkaz:
https://doaj.org/article/381264734ff34a789b289a2eb1c61cc3
Autor:
Douglas J. Norman, C. Kristian Enestvedt, Willscott E. Naugler, Rouella Erhan, Carley A. Shaut
Publikováno v:
Frontiers in Nephrology, Vol 4 (2024)
IntroductionLiver transplant recipients may have pre-formed anti-HLA antibodies directed to mismatched HLA of the liver donor (donor specific antibodies, DSA) or not directed to the liver donor (non-donor specific, non-DSA). We observed the fate of t
Externí odkaz:
https://doaj.org/article/36b723b18c8d444a99c900ce14dc5986
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
IntroductionHuman leukocyte antigen (HLA) I molecules present antigenic peptides to activate CD8+ T cells. Type 1 Diabetes (T1D) is an auto-immune disease caused by aberrant activation of the CD8+ T cells that destroy insulin-producing pancreatic β
Externí odkaz:
https://doaj.org/article/49cb6f8e6b364eab9be8df5efc5b6aa6
Publikováno v:
BMC Genomics, Vol 24, Iss 1, Pp 1-16 (2023)
Abstract Human leukocyte antigen (HLA) is closely involved in regulating the human immune system. Despite great advance in detecting classical HLA Class I binders, there are few methods or toolkits for recognizing non-classical HLA Class I binders. T
Externí odkaz:
https://doaj.org/article/3ac0f22c9f384503810b2d22c70adb06
Autor:
Lidia Giraudo, Giulia Cattaneo, Loretta Gammaitoni, Ilenia Iaia, Chiara Donini, Annamaria Massa, Maria Laura Centomo, Marco Basiricò, Elisa Vigna, Alberto Pisacane, Franco Picciotto, Enrico Berrino, Caterina Marchiò, Alessandra Merlini, Luca Paruzzo, Stefano Poletto, Daniela Caravelli, Andrea Michela Biolato, Valentina Bortolot, Elisa Landoni, Marco Ventin, Cristina R. Ferrone, Massimo Aglietta, Gianpietro Dotti, Valeria Leuci, Fabrizio Carnevale-Schianca, Dario Sangiolo
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 42, Iss 1, Pp 1-13 (2023)
Abstract Background Even acknowledging the game-changing results achieved in the treatment of metastatic melanoma with the use of immune checkpoint inhibitors (ICI), a large proportion of patients (40–60%) still fail to respond or relapse due to th
Externí odkaz:
https://doaj.org/article/3eb42d63a9594f5d95b1ee9f44199df2
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 17, p 9376 (2024)
IL-15 is a homeostatic cytokine for human T and NK cells. However, whether other cytokines influence the effect of IL-15 is not known. We studied the impact that IL-10, TGF-β, IL-17A, and IFN-γ have on the IL-15-induced proliferation of human T cel
Externí odkaz:
https://doaj.org/article/aa4ed0b24896455aa2ca05a9d9c63e77
Autor:
Akiko Mizutani, Shingo Suzuki, Atsuko Shigenari, Tadayuki Sato, Masafumi Tanaka, Jerzy K. Kulski, Takashi Shiina
Publikováno v:
Frontiers in Immunology, Vol 14 (2024)
Polymorphisms of HLA genes, which play a crucial role in presenting peptides with diverse sequences in their peptide-binding pockets, are also thought to affect HLA gene expression, as many studies have reported associations between HLA gene polymorp
Externí odkaz:
https://doaj.org/article/6576c794d9864e63b517de7fa28d8669
Publikováno v:
Kaohsiung Journal of Medical Sciences, Vol 38, Iss 12, Pp 1190-1202 (2022)
Abstract The Nod‐like receptor (NLR) family CARD domain containing 5 (NLRC5) has been reported as an activator of human leukocyte antigen (HLA) class I that is responsible for immune activity in cancer treatment. This work focuses on the role of BM
Externí odkaz:
https://doaj.org/article/7241fb377bcb4b36b4ddefe813f27a34