Zobrazeno 1 - 10
of 1 740
pro vyhledávání: '"histone-modifying enzymes"'
Publikováno v:
Heliyon, Vol 10, Iss 19, Pp e38582- (2024)
Gastric cancer, a common and severe malignancy, is associated with unfavorable outcomes and limited therapeutic options. The exploration of the potential link between plasma histone-modifying enzymes and gastric cancer through Mendelian randomization
Externí odkaz:
https://doaj.org/article/4e5cc26709144ffe9e1087965d444d6b
Autor:
Jing Wang, Jiawei Feng, Yiming Ni, Yuqing Wang, Ting Zhang, Yemin Cao, Mingmei Zhou, Cheng Zhao
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Impaired wound healing is one of the main clinical complications of type 2 diabetes (T2D) and a major cause of lower limb amputation. Diabetic wounds exhibit a sustained inflammatory state, and reducing inflammation is crucial to diabetic wounds mana
Externí odkaz:
https://doaj.org/article/812b71dd62f34c4c882641cb7c9a4082
Autor:
MengTing Wang, QingYang Chen, ShuJie Wang, Han Xie, Jun Liu, RuiXiang Huang, YuFei Xiang, YanYi Jiang, DaSheng Tian, ErBao Bian
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 42, Iss 1, Pp 1-33 (2023)
Abstract Super-enhancers (SEs) consist of multiple typical enhancers enriched at high density with transcription factors, histone-modifying enzymes and cofactors. Oncogenic SEs promote tumorigenesis and malignancy by altering protein-coding gene expr
Externí odkaz:
https://doaj.org/article/ee399d6e19fe42548aa5527d40f61ec8
Autor:
Sayuri Takahashi, Ichiro Takada
Publikováno v:
Asian Journal of Andrology, Vol 25, Iss 2, Pp 158-165 (2023)
Prostate cancer is one of the most common diseases in men worldwide. Surgery, radiation therapy, and hormonal therapy are effective treatments for early-stage prostate cancer. However, the development of castration-resistant prostate cancer has incre
Externí odkaz:
https://doaj.org/article/2b7e6afe2af6475d949514f4e25134fc
Akademický článek
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Autor:
Pin Zhao, Samiullah Malik
Publikováno v:
Cell & Bioscience, Vol 12, Iss 1, Pp 1-23 (2022)
Abstract Transcription factors directly regulate gene expression by recognizing and binding to specific DNA sequences, involving the dynamic alterations of chromatin structure and the formation of a complex with different kinds of cofactors, like DNA
Externí odkaz:
https://doaj.org/article/1c63f4510f07443eab8b54c110773da5
Autor:
Joanna Szczepanek, Andrzej Tretyn
Publikováno v:
Biomolecules, Vol 13, Iss 11, p 1590 (2023)
In the past decade, significant advances in molecular research have provided a deeper understanding of the intricate regulatory mechanisms involved in carcinogenesis. MicroRNAs, short non-coding RNA sequences, exert substantial influence on gene expr
Externí odkaz:
https://doaj.org/article/47b5300231844e27913dee1f36fa5d7e
Publikováno v:
BioImpacts, Vol 11, Iss 3, Pp 173-179 (2021)
Introduction: Histone modifying enzymes include several classes of enzymes that are responsible for various post-translational modifications of histones such as methylation and acetylation. They are important epigenetic factors, which may involve sev
Externí odkaz:
https://doaj.org/article/27ac0b1800c5465094e753b0a24959ee
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
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Autor:
Jiajia Wang, Q. Richard Lu
Publikováno v:
Neurobiology of Disease, Vol 144, Iss , Pp 105040- (2020)
Brain regeneration and tumorigenesis are complex processes involving in changes in chromatin structure to regulate cellular states at the molecular and genomic level. The modulation of chromatin structure dynamics is critical for maintaining progenit
Externí odkaz:
https://doaj.org/article/12667bc3ccdf4d5a8304550f1e3d5b8e