Zobrazeno 1 - 10
of 2 361
pro vyhledávání: '"hippocampal atrophy"'
Publikováno v:
Brain and Behavior, Vol 14, Iss 9, Pp n/a-n/a (2024)
Abstract Background Major depressive disorder (MDD) is characterized by hippocampal volume reduction, impacting cognitive function. Inflammation, particularly elevated tumor necrosis factor‐alpha (TNF‐α) levels, is consistently implicated in MDD
Externí odkaz:
https://doaj.org/article/5b12e810837344b5b494e2ee1c750042
Publikováno v:
Frontiers in Aging Neuroscience, Vol 16 (2024)
IntroductionNeurobiological changes in the hippocampus are a common consequence of aging. However, there are differences in the rate of decline and overall volume loss in people with no cognitive impairment compared to those with mild cognitive impai
Externí odkaz:
https://doaj.org/article/320e5fab348443f495da28fecadc93b7
Autor:
Kristine F. Moseholm, Jens W. Horn, Annette L. Fitzpatrick, Luc Djoussé, W. T. Longstreth, Oscar L. Lopez, Andrew N. Hoofnagle, Majken K. Jensen, Rozenn N. Lemaitre, Kenneth J. Mukamal
Publikováno v:
Frontiers in Neurology, Vol 15 (2024)
BackgroundSphingolipids are implicated in neurodegeneration and neuroinflammation. We assessed the potential role of circulating ceramides and sphingomyelins in subclinical brain pathology by investigating their association with brain magnetic resona
Externí odkaz:
https://doaj.org/article/6e63ba6d2f89482193aa64e29f5ceb0d
Autor:
Todd L. Schmitt, Judy St. Leger, Ben A. Inglis, Isabella Michal, Nancy Stedman, Hendrik H. Nollens, Sophie Dennison-Gibby, Kelsey Herrick, Elsburgh O. Clarke, Alexandra Mena, Peter F. Cook
Publikováno v:
Journal of Zoological and Botanical Gardens, Vol 4, Iss 4, Pp 665-679 (2023)
Many wild otariids (sea lions and fur seals) strand along the California coast annually with seizures following presumed exposure to harmful algal blooms (HABs). This is a long-term case study of a stranded subadult male Guadalupe fur seal (Arctoceph
Externí odkaz:
https://doaj.org/article/ad48ea7e1e424b439b9dfdc38a50431a
Autor:
Mohammad Yazdan Panah, Yousef Mokary, Sangam Shah, Sangharsha Thapa, Swati Chand, Vahid Shaygannejad, Omid Mirmosayyeb
Publikováno v:
Health Science Reports, Vol 6, Iss 9, Pp n/a-n/a (2023)
Abstract Background Parkinson's disease (PD) is one of the most common neurodegenerative conditions in the world and, when combined with dementia, can lead to immense cerebral volume loss. Of significant importance among all cerebral regions, is the
Externí odkaz:
https://doaj.org/article/769942da0205470fae9ae7f9cca31b5c
Publikováno v:
Frontiers in Neurology, Vol 14 (2023)
BackgroundThere is conflicting data regarding the predictors of Alzheimer’s Disease (AD), the most common form of dementia. The main objective of the study is to evaluate potential predictors of AD progression using a comprehensive follow-up datase
Externí odkaz:
https://doaj.org/article/c96a0ba5e8db402c8f3df34da4f9b937
Akademický článek
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Publikováno v:
BMC Neuroscience, Vol 23, Iss 1, Pp 1-12 (2022)
Abstract Background Sirtuin 1 (Sirt1) is a recognized longevity gene and has been shown to be associated with aging and its related diseases. Hippocampal volume is considered to be the most sensitive brain imaging phenotype for cognition, but the eff
Externí odkaz:
https://doaj.org/article/135b13dfa9c647ae9435e0bddd16513e
Publikováno v:
Encephalitis, Vol 2, Iss 2, Pp 58-63 (2022)
It has rarely been documented that permanent alteration of cerebral structures occurs by focal status epilepticus (FSE). We report the case of a 16-year-old boy with FSE in whom serial T1-weighted magnetic resonance volumetry and conventional magneti
Externí odkaz:
https://doaj.org/article/8e2f31d978d1412894a29c82fc75fdfe
Autor:
Tengfei Guo, Susan M. Landau, William J. Jagust, for the Alzheimer’s Disease Neuroimaging Initiative
Publikováno v:
Alzheimer’s Research & Therapy, Vol 13, Iss 1, Pp 1-12 (2021)
Abstract Background We recently reported that CSF phosphorylated tau (p-Tau181) relative to Aβ40 (CSF p-Tau/Aβ40 ratio) was less noisy and increased associations with Alzheimer’s disease (AD) biomarkers compared to CSF p-Tau181 alone. While eleva
Externí odkaz:
https://doaj.org/article/1e747bc44f474157bf2b91f5833328fb