A dynamic folded hairpin conformation is associated with α-globin activation in erythroid cells

Autor: Veronica J. Buckle, Renato Sciarretta, Jim R. Hughes, Francesco Musella, Douglas R. Higgs, Andrea Esposito, Carlo Annunziatella, A. Marieke Oudelaar, Andrea M. Chiariello, Alfonso Corrado, Martin S.C. Larke, Mattia Conte, Simona Bianco, Jelena Telenius, Luca Fiorillo, Mario Nicodemi, Antonella Prisco

Publikováno v: Cell Reports
Cell reports 30 (2020): 2125–2135.e5. doi:10.1016/j.celrep.2020.01.044
info:cnr-pdr/source/autori:Chiariello A.M.; Bianco S.; Oudelaar A.M.; Esposito A.; Annunziatella C.; Fiorillo L.; Conte M.; Corrado A.; Prisco A.; Larke M.S.C.; Telenius J.M.; Sciarretta R.; Musella F.; Buckle V.J.; Higgs D.R.; Hughes J.R.; Nicodemi M./titolo:A Dynamic Folded Hairpin Conformation Is Associated with a-Globin Activation in Erythroid Cells/doi:10.1016%2Fj.celrep.2020.01.044/rivista:Cell reports/anno:2020/pagina_da:2125/pagina_a:2135.e5/intervallo_pagine:2125–2135.e5/volume:30
Cell Reports, Vol 30, Iss 7, Pp 2125-2135.e5 (2020)

Summary: We investigate the three-dimensional (3D) conformations of the α-globin locus at the single-allele level in murine embryonic stem cells (ESCs) and erythroid cells, combining polymer physics models and high-resolution Capture-C data. Model p

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e0d3cd4df8693b657cc9034915eb1452
https://hdl.handle.net/21.11116/0000-0007-5F9C-021.11116/0000-0007-5FA0-A

Chromatin Dynamics in the Regulation of CFTR Expression

Autor: Nehal Gosalia, Ann Harris

Publikováno v: Genes
Genes, Vol 6, Iss 3, Pp 543-558 (2015)

The contribution of chromatin dynamics to the regulation of human disease-associated loci such as the cystic fibrosis transmembrane conductance regulator (CFTR) gene has been the focus of intensive experimentation for many years. Recent technological

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d45bde4e70a86e606f3ed0a4c59d0b37
http://europepmc.org/articles/PMC4584316

The Epigenetic Regulators ATRX and CTCF are Required for Mouse Neuroprogenitor Cell Survival and Brain Development

Autor: Watson, Lauren Ashley

Publikováno v: Electronic Thesis and Dissertation Repository

Emerging evidence implicates the regulation of higher-order chromatin structure in brain development, maturation, and function. Human mutations in two important regulators of chromatin structure, ATRX and CTCF, cause microcephaly and intellectual dis

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______1548::d040b531ae8c54133069b4ded7ce00fb
https://ir.lib.uwo.ca/context/etd/article/4271/viewcontent/L._Ashley_Watson__PhD_Thesis.pdf

Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.

Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.