Zobrazeno 1 - 10
of 344
pro vyhledávání: '"high-throughput RNA sequencing"'
Autor:
Liya Liu, Youqin Chen, Yuying Han, Xinran Zhang, Yulun Wu, Jing Lin, Liujing Cao, Meizhu Wu, Huifang Zheng, Yi Fang, Lihui Wei, Thomas J. Sferra, Anjum Jafri, Xiao Ke, Jun Peng, Aling Shen
Publikováno v:
Pharmaceutical Biology, Vol 62, Iss 1, Pp 607-620 (2024)
Context Ulcerative colitis has been clinically treated with Qing Hua Chang Yin (QHCY), a traditional Chinese medicine formula. However, its precise mechanisms in mitigating chronic colitis are largely uncharted.Objective To elucidate the therapeutic
Externí odkaz:
https://doaj.org/article/942f776fc7894a3895d95242b37c2669
Autor:
Linchao Sang, Luobin Ding, Kangning Hao, Ce Zhang, Xiaoyu Shen, Hui Sun, Dehao Fu, Xiangbei Qi
Publikováno v:
Journal of Orthopaedic Surgery and Research, Vol 18, Iss 1, Pp 1-14 (2023)
Abstract Objective Polymethylmethacrylate (PMMA) bone cement promotes the development of local thrombi. Our study found that a novel material, ES-PMMA bone cement, can reduce local thrombosis. We used a simple and reproducible animal model to confirm
Externí odkaz:
https://doaj.org/article/f28e41e410dd4b6484664bb2b3311621
Publikováno v:
Current Issues in Molecular Biology, Vol 45, Iss 7, Pp 6170-6189 (2023)
Long non-coding RNAs (lncRNAs) participate in acute lung injury (ALI). However, their latent biological function and molecular mechanism have not been fully understood. In the present study, the global expression profiles of lncRNAs and mRNAs between
Externí odkaz:
https://doaj.org/article/158b9cec855441ac8005cfc22af22f32
Publikováno v:
Journal of the World Aquaculture Society, Vol 54, Iss 3, Pp 764-777 (2023)
Abstract Hemibarbus maculatus is a globally important species for its value in fisheries and aquaculture. There is relatively little information available about this species' sexual development genes. Therefore, in this study, we used the technology
Externí odkaz:
https://doaj.org/article/2331baf75533441ba057a92615dada5b
Autor:
Qiuhua Bao, Xuebo Ma, Xiaoyu Bo, Jing Pang, Lixia Dai, Huiying Wang, Yongfu Chen, Lai-Yu Kwok
Publikováno v:
Frontiers in Microbiology, Vol 14 (2023)
BackgroundSome bacteria enter the viable but non-culturable (VBNC) state to survive harsh environmental conditions and external stresses. This alters cell physiology and has implications for the food industry as some bacteria, such as lactobacilli, u
Externí odkaz:
https://doaj.org/article/e17dbe65b64d40feb940881b86b89443
Autor:
Vincent Tano, Kagistia Hana Utami, Nur Amirah Binte Mohammad Yusof, Jocelyn Bégin, Willy Wei Li Tan, Mahmoud A. Pouladi, Sarah R. Langley
Publikováno v:
EBioMedicine, Vol 94, Iss , Pp 104720- (2023)
Summary: Background: In Huntington's disease (HD), a CAG repeat expansion mutation in the Huntingtin (HTT) gene drives a gain-of-function toxicity that disrupts mRNA processing. Although dysregulation of gene splicing has been shown in human HD post-
Externí odkaz:
https://doaj.org/article/0f23e04ff244494bb2dc3c59e327de67
Publikováno v:
Jichu yixue yu linchuang, Vol 42, Iss 7, Pp 1139-1143 (2022)
Aortic dilation disease, represented by aortic dissection and aortic aneurysm, is the most dangerous disease in vascular surgery. The pathogenesis of this disease is not very clear. Single-cell RNA sequencing (scRNA-seq) technology can study cell het
Externí odkaz:
https://doaj.org/article/3705f4c7695f4603b3b35deb448807cf
Autor:
Jialin Liu, Yuan Yao, Jinyong Huang, Hao Sun, Yixuan Pu, Mengting Tian, Meijie Zheng, Huiyu He, Zheng Li
Publikováno v:
BMC Genomics, Vol 23, Iss 1, Pp 1-16 (2022)
Abstract Background Long non-coding RNA (lncRNA) plays crucial role in osteogenic differentiation of bone marrow mesenchymal stem cells (BMMSCs), involving in regulation of competing endogenous RNA (ceRNA) mechanisms and conduction of signaling pathw
Externí odkaz:
https://doaj.org/article/cea97f1ea0f94f78a42a818181dcab15
Publikováno v:
PeerJ, Vol 11, p e14759 (2023)
Background Numerous studies have shown circular RNA (circRNA) dysregulation is associated with the pathogenesis of cervical cancer,particularly in individual carcinoma variants. The aim of this study is to investigate and contrastively analyze the ex
Externí odkaz:
https://doaj.org/article/235482aa3b26489f83b1dd7a44bb6316
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