Zobrazeno 1 - 10
of 714
pro vyhledávání: '"high-altitude hypoxia"'
Publikováno v:
Heliyon, Vol 10, Iss 20, Pp e38220- (2024)
Background: This study investigates the molecular mechanisms behind firmicutes-mediated macrophage (Mψ) polarization and glycolytic metabolic reprogramming through HIF-1α in response to intrinsic mucosal barrier injury induced by high-altitude hypo
Externí odkaz:
https://doaj.org/article/a9341dc611f5481d8eb624653c1d4912
Autor:
Chongyi Ai, Jin Bai, Qingsong Ye, Siyu Niu, Yunzhe Li, Pan Li, Hao Wu, Jinhui Wu, Xinxing Wang
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 179, Iss , Pp 117247- (2024)
High altitude environment is mainly characterized by low oxygen. Due to persistent hypoxia, nonhealing wounds are common in high-altitude areas. Moreover, Basic fibroblast growth factor (bFGF) is a versatile biologically active substance that has cru
Externí odkaz:
https://doaj.org/article/c7d04d1d8bbd43d7ac7847b492f8b7c3
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
Background: The primary constituent of ginseng, known as ginsenosides (GS), has been scientifically demonstrated to possess anti-fatigue, anti-hypoxia, anti-inflammatory, and antioxidant properties. However, the effect and mechanisms of GS on tissue
Externí odkaz:
https://doaj.org/article/67f3596155ed4484819747b56fd6d007
Autor:
Renjie Wang, Shuhe Ma, Jun Yang, Kai Luo, Qingyuan Qian, Jinchao Pan, Keke Liang, Yihao Wang, Yue Gao, Maoxing Li
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 19, p 10734 (2024)
Hydrogen sulfide (H2S), as a key gas signaling molecule, plays an important role in regulating various diseases, with appropriate concentrations providing antioxidative, anti-inflammatory, and anti-apoptotic effects. The specific role of H2S in acute
Externí odkaz:
https://doaj.org/article/7764062402ab4c23888f94ee192899f7
Autor:
Doudou Hao, Haomeng Niu, Qin Zhao, Jing Shi, Chuanhao An, Siyu Wang, Chaohua Zhou, Siyuan Chen, Yongxing Fu, Yongqun Zhang, Zeng He
Publikováno v:
Frontiers in Microbiology, Vol 15 (2024)
IntroductionIntestinal microorganisms play an important role in the health of both humans and animals, with their composition being influenced by changes in the host’s environment.MethodsWe evaluated the longitudinal changes in the fecal microbial
Externí odkaz:
https://doaj.org/article/1ec5fd40a66c42d2938352079b184a56
Publikováno v:
环境与职业医学, Vol 40, Iss 11, Pp 1297-1306 (2023)
BackgroundPlateau environment may pose a serious impact on the physiological and psychological stress of people stationed on a plateau, especially for those engaged in military training and occupational activities. There is an urgent need to find dru
Externí odkaz:
https://doaj.org/article/19305e8066294f0087f81b26c5e3157b
Autor:
Xue Geng, Chaoyi Qu, Lina Zhao, Jianhong Zhang, Peng Huang, Derun Gao, Qiangman Wei, Fei Qin, Jiexiu Zhao
Publikováno v:
Sports Medicine and Health Science, Vol 5, Iss 2, Pp 83-90 (2023)
As an invisible “endocrine organ”, gut microbiota is widely involved in the regulation of nervous system, endocrine system, circulatory system, and digestive system. It is also closely related to host health and the occurrence of many chronic dis
Externí odkaz:
https://doaj.org/article/bc24fcaa30dd4c1f819e1a88f6db1e6e
Autor:
Yu Huan, Huilin Quan, Bo Jia, Guangzhi Hao, Zuolin Shi, Tianzi Zhao, Ying Yuan, Fang Yuan, Yushu Dong, Guobiao Liang
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 16 (2023)
IntroductionNeuronal cell death is an important factor in the pathogenesis of acute high-altitude cerebral hypoxia; however, the underlying molecular mechanism remains unclear. In this study, we tested if high-altitude hypoxia (HAH) causes neuronal d
Externí odkaz:
https://doaj.org/article/33037ae6b2e64af9a3125c422ae2c617
Autor:
Zhaohua He, Shaobin Li, Fangfang Zhao, Hongxian Sun, Jiang Hu, Jiqing Wang, Xiu Liu, Mingna Li, Zhidong Zhao, Yuzhu Luo
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 1, p 385 (2023)
The Tibetan sheep has an intricate mechanism of adaptation to low oxygen levels, which is influenced by both genetic and environmental factors. The heart plays a crucial role in the adaptation of Tibetan sheep to hypoxia. In the present study, we uti
Externí odkaz:
https://doaj.org/article/808a25d549154d00af3ae3eb1aeea176
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