Zobrazeno 1 - 10
of 219
pro vyhledávání: '"hexokinases"'
Autor:
Akachukwu Ibezim, Emmanuel Onah, Sochi Chinaemerem Osigwe, Peter Ukwu Okoroafor, Onyeoziri Pius Ukoha, Jair Lage de Siqueira-Neto, Fidele Ntie-Kang, Karuppasamy Ramanathan
Publikováno v:
Scientific African, Vol 24, Iss , Pp e02226- (2024)
Hexokinases (Hks) and mitochondrial complex I (MCI) are involved in the energy metabolism of cells; glycolysis/fermentation and oxidative phosphorylation. Both Hks and MCI are known to play critical roles in either division of metabolic plasticity wh
Externí odkaz:
https://doaj.org/article/7ea008155e0f4fa6b3feaa9455870ef6
Autor:
Melina Shamshoum, Ofir Aharon Kuperman, Sapir Korman Shadmi, Maxim Itkin, Sergey Malitsky, Filipe Natalio
Publikováno v:
Frontiers in Plant Science, Vol 14 (2023)
Fluorescent glucose derivatives are valuable tools as glucose analogs in plant research to explore metabolic pathways, study enzyme activity, and investigate cellular processes related to glucose metabolism and sugar transport. They allow visualizati
Externí odkaz:
https://doaj.org/article/7137c0dba83743529c657de37ffb8321
Publikováno v:
Thoracic Cancer, Vol 12, Iss 23, Pp 3184-3193 (2021)
Abstract Background Activation of ALK leads to a high level of aerobic glycolysis related to crizotinib insensitivity in anaplastic lymphoma kinase‐positive non‐small cell lung cancer (ALK+ NSCLC). The strategy and mechanism of glycolysis inhibit
Externí odkaz:
https://doaj.org/article/4bb9d66354ef4b3b930a41e96b102ed7
Publikováno v:
Life, Vol 13, Iss 4, p 946 (2023)
Hexokinases (HKs) convert hexose sugars to hexose-6-phosphate, thus trapping them inside cells to meet the synthetic and energetic demands. HKs participate in various standard and altered physiological processes, including cancer, primarily through t
Externí odkaz:
https://doaj.org/article/7255f7cadf464792acdf98f36a52b284
Akademický článek
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Publikováno v:
Frontiers in Pharmacology, Vol 9 (2018)
ORY-1001, an inhibitor of covalent lysine (K)-specific demethylase 1A (KDM1A), has been used as a therapy for the treatment of acute leukemia. However, the underlying mechanisms of anticancer are still not fully elucidated. Here, we report that KDM1A
Externí odkaz:
https://doaj.org/article/7a298581114544a1ad16eb8798c54fc8
Akademický článek
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Autor:
Gelei Xiao, Dingyang Liu, Jun Huang, Gang Peng, Zhiquan Yang, Qing Liu, Jian Yuan, Zhuanyi Yang
Publikováno v:
Journal of Cancer
Deregulation of aerobic glycolysis is a common phenomenon in human cancers, including glioblastoma (GBM). In the present study, we demonstrated that the natural compound xanthohumol has a profound anti-tumor effect on GBM via direct inhibition of gly
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a1b26e48c584e329fd009f6e832c4d90
https://doi.org/10.7150/jca.33045
https://doi.org/10.7150/jca.33045
Autor:
Ozge Kilicoglu, Nayim Sepay, Emre Ozgenc, Evren Gundogdu, Umit Kara, Sultan Alomairy, M.S. Al-Buriahi
Publikováno v:
Applied Radiation and Isotopes. 191:110553
Fluorodeoxyglucose (FDG), marked with the most used Positron Emission Tomography (PET) radiopharmaceutical Fluorine-18 (F-18), is a glucose analog and is taken to living cells through membrane glucose carriers. F-18 FDG involvement in tissue is propo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b77bbd75ddfe40523d14ac4a69b3b343
https://doi.org/10.1016/j.apradiso.2022.110553
https://doi.org/10.1016/j.apradiso.2022.110553
Akademický článek
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