Zobrazeno 1 - 10
of 46
pro vyhledávání: '"heteromeric channel"'
Publikováno v:
Frontiers in Pharmacology, Vol 4 (2013)
Externí odkaz:
https://doaj.org/article/19b205d7f65b44b2a6acc0b3af74f7c5
Publikováno v:
Frontiers in Pharmacology, Vol 4 (2013)
Connexin43 (Cx43) is widely expressed in many different tissues of the human body. In cells of some organs, Cx43 is co-expressed with other connexins (Cx), including Cx46 and Cx50 in lens, Cx40 in atrium, Purkinje fibers, and the blood vessel wall, C
Externí odkaz:
https://doaj.org/article/6d80d6802e2243ce99aa2126ba3b1f36
Autor:
Michael C. Bassik, Xiaolin Wen, Rachel E. Mardjuki, Merritt Maduke, Böhnert, Christopher Ritchie, Lauren J. Lahey, Jacqueline A. Carozza, Gaelen T. Hess, Lingyin Li
SUMMARYExtracellular 2’3’-cyclic-GMP-AMP (cGAMP) is an immunotransmitter secreted by cancer cells and taken up by host cells to activate the anti-cancer STING pathway. No cGAMP exporter has been identified, and SLC19A1, a recently identified cGAM
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d9f30e9f389ebc06a01738122ee0954
https://doi.org/10.1101/2020.02.13.948273
https://doi.org/10.1101/2020.02.13.948273
Autor:
Vincent L. Salgado
Publikováno v:
Journal of Pesticide Science. 42:1-6
This review provides a brief overview of ion channels, then focuses on TRP channels, describing the properties and functions of the seven TRP channel classes found in insects. Finally, recent work showing that a heteromeric channel composed of Nanchu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d067bdbbe66cb0aecf41b950bad9368
https://doi.org/10.1584/jpestics.d16-104
https://doi.org/10.1584/jpestics.d16-104
Publikováno v:
The Journal of General Physiology
Strange et al. review recent advances in our understanding of the molecular and structural basis of volume-regulated anion channel function within the framework of classical biophysical and physiological studies.
The swelling-activated anion cha
The swelling-activated anion cha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b1b3cd8fc87073fb496acac0f2419bb
https://pubmed.ncbi.nlm.nih.gov/30651298
https://pubmed.ncbi.nlm.nih.gov/30651298
Autor:
Rubaiy, HN, Ludlow, MJ, Henrot, M, Gaunt, HJ, Miteva, K, Cheung, SY, Tanahashi, Y, Hamzah, N, Musialowski, KE, Blythe, NM, Appleby, HL, Bailey, MA, McKeown, L, Taylor, R, Foster, R, Waldmann, H, Nussbaumer, P, Christmann, M, Bon, RS, Muraki, K, Beech, DJ
Publikováno v:
The Journal of Biological Chemistry
The concentration of free cytosolic Ca(2+) and the voltage across the plasma membrane are major determinants of cell function. Ca(2+)-permeable non-selective cationic channels are known to regulate these parameters but understanding of these channels
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::1f997a930b498b96cb147d4631e98d2b
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Biomembranes. 1808(12):2789-2797
We previously reported that TRPV4 and TRPC1 can co-assemble to form heteromeric TRPV4–C1 channels [12]. In the present study, we characterized some basic electrophysiological properties of heteromeric TRPV4–C1 channels. 4α-Phorbol 12,13-didecano
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c46adb0940e5de79b0e22570b26ee88
Publikováno v:
Biochemical and Biophysical Research Communications
The inwardly-rectifying potassium channel subunit Kir5.1 selectively co-assembles with members of the Kir4.0 subfamily to form novel pH-sensitive heteromeric channels with unique single channel properties. In this study, we have cloned orthologs of K
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::28ed3e6d95658e027676ae52a2e7533c
http://europepmc.org/articles/PMC2764340
http://europepmc.org/articles/PMC2764340
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Biomembranes. 1758(11):1837-1845
Inwardly rectifying K+ channels (Kir) comprise seven subfamilies that can be subdivided further on the basis of cytosolic pH (pHi) sensitivity, rectification strength and kinetics, and resistance to run-down. Although distinct residues within each ch
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fe1b188942188abab90646291669975b
Autor:
Carlos A. Villalba-Galea
Publikováno v:
Biophysical Journal. 112:110a
KV7 channels are critical components of the plasma membrane in many excitable cells. The main function of KV7 channels is to contribute to the maintenance of the resting potential, thus regulating cellular electrical excitability. In Central Nervous
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ee60e533b96781da6fd896158dfc6739
https://doi.org/10.1016/j.bpj.2016.11.624
https://doi.org/10.1016/j.bpj.2016.11.624