A Functional Polymorphism in Accessible Chromatin Region Confers Risk of Non-Small Cell Lung Cancer in Chinese Population

Autor: Jieyi Long, Tingting Long, Ying Li, Peihong Yuan, Ke Liu, Jiaoyuan Li, Liming Cheng

Publikováno v: Frontiers in Oncology, Vol 11 (2021)

BackgroundThe disease-associated non-coding variants identified by genome-wide association studies (GWASs) were enriched in open chromatin regions (OCRs) and implicated in gene regulation. Genetic variants in OCRs thus may exert regulatory functions

Externí odkaz: https://doaj.org/article/f1000c51b5104a17a6f842a19607fd86

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Cancer-targeted IL-12 controls human rhabdomyosarcoma by senescence induction and myogenic differentiation.

Autor: Schilbach K; Department of General Pediatrics; Oncology/Hematology; University Children's Hospital ; Tübingen, Germany., Alkhaled M; Department of General Pediatrics; Oncology/Hematology; University Children's Hospital ; Tübingen, Germany., Welker C; Department of General Pediatrics; Oncology/Hematology; University Children's Hospital ; Tübingen, Germany., Eckert F; Department of Radiation Oncology; Eberhard Karls University ; Tübingen, Germany., Blank G; Department of General, Visceral and Transplant Surgery; University Hospital ; Tübingen, Germany., Ziegler H; Department of General Pediatrics; Oncology/Hematology; University Children's Hospital ; Tübingen, Germany., Sterk M; Department of General Pediatrics; Oncology/Hematology; University Children's Hospital ; Tübingen, Germany., Müller F; Department of General Pediatrics; Oncology/Hematology; University Children's Hospital ; Tübingen, Germany., Sonntag K; Department of General Pediatrics; Oncology/Hematology; University Children's Hospital ; Tübingen, Germany., Wieder T; Department of Dermatology; Eberhard Karls University ; Tübingen, Germany., Braumüller H; Department of Dermatology; Eberhard Karls University ; Tübingen, Germany., Schmitt J; Werner Siemens Imaging Center; Department for Preclinical Imaging and Radiopharmacy; Eberhard Karls University ; Tübingen, Germany., Eyrich M; University of Würzburg; Department of Pediatrics; Interdisciplinary Stem Cell Laboratory ; Würzburg, Germany., Schleicher S; Department of General Pediatrics; Oncology/Hematology; University Children's Hospital ; Tübingen, Germany., Seitz C; Department of General Pediatrics; Oncology/Hematology; University Children's Hospital ; Tübingen, Germany., Erbacher A; Department of General Pediatrics; Oncology/Hematology; University Children's Hospital ; Tübingen, Germany., Pichler BJ; Werner Siemens Imaging Center; Department for Preclinical Imaging and Radiopharmacy; Eberhard Karls University ; Tübingen, Germany., Müller H; Department of General Pathology; Institute of Pathology; Eberhard Karls University ; Tübingen, Germany., Tighe R; EMD Serono Research Institute ; Billerica, MA USA., Lim A; Départment d'Immunologie; Institute Pasteur ; Paris, France., Gillies SD; Provenance Biopharmaceuticals ; Carlisle, MA USA., Strittmatter W; Merck Serono R&D; Global Early Development; Merck KGaA ; Darmstadt, Germany., Röcken M; Department of Dermatology; Eberhard Karls University ; Tübingen, Germany., Handgretinger R; Department of General Pediatrics; Oncology/Hematology; University Children's Hospital ; Tübingen, Germany.

Publikováno v: Oncoimmunology [Oncoimmunology] 2015 Mar 19; Vol. 4 (7), pp. e1014760. Date of Electronic Publication: 2015 Mar 19 (Print Publication: 2015).