Zobrazeno 1 - 10
of 329
pro vyhledávání: '"hereditary ovarian cancer"'
Publikováno v:
Journal of Current Oncology and Medical Sciences, Vol 4, Iss 3, Pp 857-874 (2024)
Ovarian cancer (OC) remains one of the most lethal gynecological malignancies, primarily due to its often late-stage diagnosis and the development of resistance to conventional therapies. In recent years, significant advancements in immunotherapy hav
Externí odkaz:
https://doaj.org/article/dc398e9e146541e5a49ed1d4764d810d
Autor:
D. S. Prokofyeva, E. T. Mingazheva, Ya. V. Valova, D. D. Sakaeva, R. R. Faishanova, A. Kh. Nurgalieva, R. R. Valiev, N. Bogdanova, T. Dörk, E. K. Khusnutdinova
Publikováno v:
Journal of Ovarian Research, Vol 16, Iss 1, Pp 1-8 (2023)
Abstract About 5–10% of all ovarian cancer cases show familial clustering, and some 15–25% of familial ovarian cancer cases are mediated by high-penetrance mutations in the BRCA1 and BRCA2 genes. Only few other genes have been identified for fami
Externí odkaz:
https://doaj.org/article/1c806737a7154808ae75ff4705377b03
Publikováno v:
Сибирский онкологический журнал, Vol 21, Iss 5, Pp 123-134 (2022)
Background. Hereditary genetic mutations are a significant risk factor for malignant transformation of cells and cancer development. Hereditary genetic mutations account for 15 to 25 % of all ovarian carcinomas. Purpose of the study: to summarize dat
Externí odkaz:
https://doaj.org/article/d3954e4825e14a9bb93d9b5fdb3c4b21
Autor:
FENG Zheng, WEN Hao
Publikováno v:
Zhongguo aizheng zazhi, Vol 32, Iss 11, Pp 1044-1048 (2022)
Ovarian cancer is one of the most common and lethal diseases among females. Due to the difficulty of surveillance and early detection, most ovarian cancers were diagnosed at advanced stage with poor outcomes. Epidemiological studies indicate that wom
Externí odkaz:
https://doaj.org/article/093fee4116f94a65ba49c3e9a50379bd
Autor:
Emma Lund Johansen, Christine Fribert Thusgaard, Mads Thomassen, Susanne Eriksen Boonen, Kirsten Marie Jochumsen
Publikováno v:
Gynecologic Oncology Reports, Vol 44, Iss , Pp 101105- (2022)
The risk of ovarian, tubal, and peritoneal cancer is related to germline pathogenic variants, and over time, the number of known disease-associated genes has increased significantly. This study reviews the literature regarding the topic from a histor
Externí odkaz:
https://doaj.org/article/f885b7ad64b348a88a87b17ce5658b16
Akademický článek
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Autor:
R. R. Faiskhanova, D. D. Sakaeva
Publikováno v:
Медицинский совет, Vol 0, Iss 4S, Pp 114-119 (2021)
When we talk about hereditary ovarian cancer, we usually mean BRCA – associated cancer. Detection of hereditary ovarian cancer is important for the prevention of cancer in blood relatives of mutation carriers, and also makes it possible to use PARP
Externí odkaz:
https://doaj.org/article/34de5d8513344d83a4ae33df9ec72b88
Autor:
Shelly Cummings, Susana San Roman, Jennifer Saam, Ryan Bernhisel, Krystal Brown, Johnathan M. Lancaster, Lydia Usha
Publikováno v:
Journal of Ovarian Research, Vol 14, Iss 1, Pp 1-7 (2021)
Abstract Background Professional society guidelines recommend risk-reducing salpingo-oophorectomy (RRSO) for women with pathogenic variants (PVs) in ovarian cancer-risk genes. Personalization of that intervention is based on gene-specific phenotypes;
Externí odkaz:
https://doaj.org/article/c8345c1edcca47cc9f2904770d06caa4
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
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Autor:
Marion Kiechle, Ricarda Dukatz, Maryam Yahiaoui-Doktor, Anika Berling, Maryam Basrai, Vera Staiger, Uwe Niederberger, Nicole Marter, Jacqueline Lammert, Sabine Grill, Katharina Pfeifer, Kerstin Rhiem, Rita K. Schmutzler, Matthias Laudes, Michael Siniatchkin, Martin Halle, Stephan C. Bischoff, Christoph Engel
Publikováno v:
BMC Cancer, Vol 17, Iss 1, Pp 1-11 (2017)
Abstract Background Women with pathogenic BRCA germline mutations have an increased risk for breast and ovarian cancer that seems to be modified by life-style factors. Though, randomized trials investigating the impact of lifestyle interventions on c
Externí odkaz:
https://doaj.org/article/ad514f21b32743c2ac3f7fc9843f6081