Zobrazeno 1 - 10
of 10 037
pro vyhledávání: '"hepatocellular carcinoma/HCC"'
Autor:
Zhipeng Zhu, Huang Cao, Hongyu Yan, Hanzhi Liu, Zaifa Hong, Anran Sun, Tong Liu, Fengbiao Mao
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 23, Iss , Pp 929-941 (2024)
Cancer immunotherapy has shown to be a promising method in treating hepatocellular carcinoma (HCC), but suboptimal responses in patients are attributed to cellular and molecular heterogeneity. Iron metabolism-related genes (IRGs) are important in mai
Externí odkaz:
https://doaj.org/article/8dfb45de7eba49c2b458a98ee300c728
Autor:
Yang Xiao, Ping Tao, Keke Zhang, Liuyan Chen, Jinyu Lv, Zhiwei Chen, Lu He, Hongling Jia, Jian Sun, Mingrong Cao, Jian Hong, Chen Qu
Publikováno v:
Molecular Cancer, Vol 23, Iss 1, Pp 1-17 (2024)
Abstract Background Myofibroblasts constitute a significant component of the tumor microenvironment (TME) and play a pivotal role in the progression of hepatocellular carcinoma (HCC). Integrin α5 (ITGA5) is a crucial regulator in myofibroblasts of m
Externí odkaz:
https://doaj.org/article/23dee5b894504f2486997dc86229e926
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-8 (2024)
Abstract The molecular profile of paracancerous tissue has been reported to be prognostic for recurrence in patients with different cancers. This study investigated the clinical significance of the protein expression of gamma-butyrobetaine hydroxylas
Externí odkaz:
https://doaj.org/article/687366ce53aa47c4997d6123a6f37f2b
Autor:
Yiyue Huang, Yuexiang Su, Yuanyuan Chen, Jingxuan Xu, Lu Zhu, Haowen Wei, Shuiling Qin, Yuchong Peng, Lunan Qi
Publikováno v:
World Journal of Surgical Oncology, Vol 22, Iss 1, Pp 1-12 (2024)
Abstract Purpose This study aimed to develop postsurgical progression/hyperprogression recurrence (type III-IV recurrence) prediction models for hepatocellular carcinoma (HCC) patients with macroscopic vascular invasion (MaVI) and to guide treatment
Externí odkaz:
https://doaj.org/article/0f79eb16189d43099251a74a591a24d6
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-11 (2024)
Abstract Metabolic dysfunction-associated steatohepatitis (MASH) is a form of chronic liver inflammation associated with metabolic syndrome, such as obesity and a major cause of hepatocellular carcinoma (HCC). Multi-biotics, a soymilk fermented with
Externí odkaz:
https://doaj.org/article/83b07d903e25454c87f85ae0e42d6b27
Publikováno v:
Kaohsiung Journal of Medical Sciences, Vol 40, Iss 11, Pp 962-971 (2024)
Abstract Universal neonatal hepatitis B virus (HBV) vaccination and the advent of direct‐acting antivirals (DAA) against hepatitis C virus (HCV) have reshaped the epidemiology of chronic liver diseases. However, some aspects of the management of ch
Externí odkaz:
https://doaj.org/article/d27f7333d42a4c2fbc4ecc66fdfcce63
Publikováno v:
Discover Oncology, Vol 15, Iss 1, Pp 1-20 (2024)
Abstract Hepatocellular carcinoma (HCC) is a highly heterogeneous malignancy with poor prognosis and a common cause of cancer-related death worldwide, and despite ongoing therapeutic breakthroughs, patient survival benefits are limited. Severe acute
Externí odkaz:
https://doaj.org/article/6b7a76b210bb436fa7aca876344d2d34
Autor:
Azza Mahmoud El Sheashaey, Marium Nagah Al Zafrany Al Agha, Amr ragab Ibrahim shalaby, Salah Mohammed El Kousy, Gamalate Abd Ellatef Elgedawy
Publikováno v:
Egyptian Liver Journal, Vol 14, Iss 1, Pp 1-16 (2024)
Abstract Background Metabolomics is an emerging field that quantifies numerous metabolites systematically aiming to determine the metabolites corresponding to each biological phenotype and then provide an analysis of the mechanisms involved. Bile aci
Externí odkaz:
https://doaj.org/article/50ce4b4ebf84436f8200f2d2c37d75c3
Autor:
Reem Amr Assal, Rowan Bahaa El-din Abd El-bary, Rana A. Youness, Mohamed Mamdouh Abdelrahman, Hala Zahran, Karim Adel Hosny, Gamal Esmat, Kai Breuhahn, Nada El-Ekiaby, Injie Omar Fawzy, Ahmed Ihab Abdelaziz
Publikováno v:
BMC Gastroenterology, Vol 24, Iss 1, Pp 1-14 (2024)
Abstract Background Proteoglycans are important tumor microenvironment extracellular matrix components. The regulation of key proteoglycans, such as decorin (DCN), by miRNAs has drawn attention since they have surfaced as novel therapeutic targets in
Externí odkaz:
https://doaj.org/article/c9d22e2133164cdab906dc815247e5e7
Publikováno v:
Liver Research, Vol 8, Iss 3, Pp 141-151 (2024)
Hepatocellular carcinoma (HCC) is the sixth most prevalent form of cancer globally and the third leading cause of cancer-related mortality. The incidence of portal vein tumor thrombosis (PVTT) in HCC patients is 21% at one year and 46% at three years
Externí odkaz:
https://doaj.org/article/0a485adec1b34749b96133a23bf52e4f