Zobrazeno 1 - 10
of 249
pro vyhledávání: '"hepatoblast"'
Autor:
Jie Deng, Kai Luo, Pengchao Xu, Qingyuan Jiang, Yuan Wang, Yunqi Yao, Xiaolei Chen, Fuyi Cheng, Dan Xie, Hongxin Deng
Publikováno v:
Stem Cell Research & Therapy, Vol 12, Iss 1, Pp 1-16 (2021)
Abstract Background Direct reprogramming of human fibroblasts to hepatocyte-like cells was proposed to generate large-scale functional hepatocytes demanded by liver tissue engineering. However, the difficulty in obtaining large quantities of human fi
Externí odkaz:
https://doaj.org/article/ed601e530c7041199a4a080c7c909779
Autor:
Tingcai Pan, Jiawang Tao, Yan Chen, Jiaye Zhang, Anteneh Getachew, Yuanqi Zhuang, Ning Wang, Yingying Xu, Shenglin Tan, Ji Fang, Fan Yang, Xianhua Lin, Kai You, Yi Gao, Yin-xiong Li
Publikováno v:
Stem Cell Research & Therapy, Vol 12, Iss 1, Pp 1-13 (2021)
Abstract Background Chemically strategies to generate hepatic cells from human pluripotent stem cells (hPSCs) for the potential clinical application have been improved. However, producing high quality and large quantities of hepatic cells remain chal
Externí odkaz:
https://doaj.org/article/eab6c58f0e3544548efa07f3885e9cf4
Publikováno v:
Journal of the Formosan Medical Association, Vol 119, Iss 6, Pp 1041-1051 (2020)
Background/purpose: To investigate the role of microRNA (miRNA) dysregulation in liver cancer by assessing the miRNA profiles of human hepatic stem cells (HpSCs), marker-carrying human hepatoblastoma (HB) cells, and hepatocellular carcinoma (HCC) cel
Externí odkaz:
https://doaj.org/article/8012a36c59424ef1b9bc9cf070d9be2c
Autor:
Xianliang Hou, Yane Yang, Ping Li, Zhipeng Zeng, Wenlong Hu, Ruilian Zhe, Xinqiong Liu, Donge Tang, Minglin Ou, Yong Dai
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
The liver is one of vital organs of the human body, and it plays an important role in the metabolism and detoxification. Moreover, fetal liver is one of the hematopoietic places during ontogeny. Understanding how this complex organ develops during em
Externí odkaz:
https://doaj.org/article/dd857f10f0c74a4b8568b018b5e08393
Autor:
Koki Yoshimoto, Nicolas Minier, Jiandong Yang, Satoshi Imamura, Kaylene Stocking, Janmesh Patel, Shiho Terada, Yoshikazu Hirai, Ken-ichiro Kamei
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 8 (2020)
Hepatic development requires multiple sequential physicochemical environmental changes in an embryo, and human pluripotent stem cells (hPSCs) allow for the elucidation of this embryonic developmental process. However, the current in vitro methods for
Externí odkaz:
https://doaj.org/article/2e1477a339094a309d06c9ab38a48210
Autor:
Diehl, A. M., Reid, L. M.
Publikováno v:
In Vitro Cellular & Developmental Biology. Animal, 1998 Mar 01. 34(3), 247-258.
Externí odkaz:
https://www.jstor.org/stable/4294754
Akademický článek
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Akademický článek
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Publikováno v:
Journal of Cellular and Molecular Medicine
Oestradiol (E2) is a critical factor for multiple systems' development during the embryonic period. Here, we aimed to investigate the effects of oestradiol on intrahepatic bile duct development, which may allow a better understanding of congenital bi
Publikováno v:
Stem Cell Reports, Vol 7, Iss 2, Pp 158-166 (2016)
In the early fetal liver, hematopoietic progenitors expand and mature together with hepatoblasts, the liver progenitors of hepatocytes and cholangiocytes. Previous analyses of human fetal livers indicated that both progenitors support each other's li
Externí odkaz:
https://doaj.org/article/70e08fef68ef4a0f9b34a39e67d18da1