Zobrazeno 1 - 10
of 2 180
pro vyhledávání: '"hepatic ischemia reperfusion"'
Publikováno v:
Iranian Journal of Basic Medical Sciences, Vol 27, Iss 10, Pp 1323-1330 (2024)
Objective(s): Hepatic ischemia-reperfusion (HIR) is a severe process in pathophysiology that occurs clinically in hepatectomy, and hepatic transplantations. The present study aimed to investigate the effect of PKC θ deletion against HIR injury and e
Externí odkaz:
https://doaj.org/article/61518b881be149e89fec08374aecf8f7
Autor:
Meng-Qi Dong, Yuan Xie, Zhi-Liang Tang, Xue-Wen Zhao, Fu-Zhen Lin, Guang-Yu Zhang, Zhi-Hao Huang, Zhi-Min Liu, Yuan Lin, Feng-Yong Liu, Wei-Jie Zhou
Publikováno v:
Liver Research, Vol 8, Iss 3, Pp 165-171 (2024)
Background and aim: Hepatic ischemia–reperfusion injury (IRI) is a significant challenge in liver transplantation, trauma, hypovolemic shock, and hepatectomy, with limited effective interventions available. This study aimed to investigate the role
Externí odkaz:
https://doaj.org/article/a1b8e730d358405c822d3f35b512507a
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-24 (2024)
Abstract Hepatic ischemia-reperfusion injury (HIRI) may cause severe hepatic impairment, acute hepatic insufficiency, and multiorgan system collapse. Exosomes can alleviate HIRI. Therefore, this study explored the role of exosomal-related genes (ERGs
Externí odkaz:
https://doaj.org/article/1ea6564c411849c2a858bd817e30910b
Autor:
Yi Xiong, Jiawen Chen, Wei Liang, Kun Li, Yingqi Huang, Jingwen Song, Baoyu Zhang, Xiusheng Qiu, Dongbo Qiu, Qi Zhang, Yunfei Qin
Publikováno v:
Journal of Translational Medicine, Vol 22, Iss 1, Pp 1-16 (2024)
Abstract Background Liver surgery during the perioperative period often leads to a significant complication known as hepatic ischemia-reperfusion (I/R) injury. Hepatic I/R injury is linked to the innate immune response. The cGAS-STING pathway trigger
Externí odkaz:
https://doaj.org/article/036a65c91ca34544a116b3ba95110ba0
Autor:
ZHANG Xiangxin, LI Wen
Publikováno v:
Jichu yixue yu linchuang, Vol 44, Iss 6, Pp 877-881 (2024)
In case of hepatic ischemia-reperfusion injury (HIRI), mitophagy is induced by multiple pathways such as PINK1/Parkin and mitophagy receptor, which is closely related to mitochondrial dynamic related protein. Mitophagy is a double-edged sword. Modera
Externí odkaz:
https://doaj.org/article/bfb844eafda54c42b8e1f2e698f81e9e
Publikováno v:
Molecular Biomedicine, Vol 5, Iss 1, Pp 1-17 (2024)
Abstract Hepatic ischemia–reperfusion injury (HIRI) is a critical pathophysiological process during liver transplantation (LT). Multiple genes and signal pathways are dysregulated during HIRI. This study aims to identify genes as potential therapeu
Externí odkaz:
https://doaj.org/article/3ebd386c312c4a66add634bc85c6e4e3
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-13 (2024)
Abstract 6-Gingerol, the main bioactive compound of ginger, has antioxidant, anti-inflammatory, anti-cancer and neuroprotective effects. However, it is unclear whether 6-Gingerol has protective effects against hepatic ischemia/reperfusion (I/R) injur
Externí odkaz:
https://doaj.org/article/b2095ab35f3b453b98fb348024ec64b3
Publikováno v:
BMC Anesthesiology, Vol 24, Iss 1, Pp 1-13 (2024)
Abstract Background Animal experiments have confirmed that remote ischemic preconditioning (RIPC) can reduce hepatic ischemia-reperfusion injuries (HIRIs), significantly improving early tissue perfusion and oxygenation of the residual liver after res
Externí odkaz:
https://doaj.org/article/139e214b10324d59a41607b42bb8b055
Autor:
Leiyi Zhang, Xiaoxiang Gong, Juan Tan, Rongsen Zhang, Mingxia Li, Cong Liu, Chenhao Wu, Xiaojing Li
Publikováno v:
Biology Direct, Vol 19, Iss 1, Pp 1-13 (2024)
Abstract Background This study seeks to investigate the impacts of Lactobacillus reuteri (L. reuteri) on hepatic ischemia-reperfusion (I/R) injury and uncover the mechanisms involved. Methods Mice in the I/R groups were orally administered low and hi
Externí odkaz:
https://doaj.org/article/ff0395ea685f4264a1ce1c6185885db6
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-15 (2024)
Abstract Hepatic ischemia–reperfusion injury (HIRI) elicits an immune-inflammatory response that may result in hepatocyte necrosis and apoptosis, ultimately culminating in postoperative hepatic dysfunction and hepatic failure. The precise mechanism
Externí odkaz:
https://doaj.org/article/88f5e7d84dec46bdaf6a0eb60a069123