Zobrazeno 1 - 10
of 3 600
pro vyhledávání: '"hepatic ischemia"'
Publikováno v:
Iranian Journal of Basic Medical Sciences, Vol 27, Iss 10, Pp 1323-1330 (2024)
Objective(s): Hepatic ischemia-reperfusion (HIR) is a severe process in pathophysiology that occurs clinically in hepatectomy, and hepatic transplantations. The present study aimed to investigate the effect of PKC θ deletion against HIR injury and e
Externí odkaz:
https://doaj.org/article/61518b881be149e89fec08374aecf8f7
Autor:
Meng-Qi Dong, Yuan Xie, Zhi-Liang Tang, Xue-Wen Zhao, Fu-Zhen Lin, Guang-Yu Zhang, Zhi-Hao Huang, Zhi-Min Liu, Yuan Lin, Feng-Yong Liu, Wei-Jie Zhou
Publikováno v:
Liver Research, Vol 8, Iss 3, Pp 165-171 (2024)
Background and aim: Hepatic ischemia–reperfusion injury (IRI) is a significant challenge in liver transplantation, trauma, hypovolemic shock, and hepatectomy, with limited effective interventions available. This study aimed to investigate the role
Externí odkaz:
https://doaj.org/article/a1b8e730d358405c822d3f35b512507a
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-24 (2024)
Abstract Hepatic ischemia-reperfusion injury (HIRI) may cause severe hepatic impairment, acute hepatic insufficiency, and multiorgan system collapse. Exosomes can alleviate HIRI. Therefore, this study explored the role of exosomal-related genes (ERGs
Externí odkaz:
https://doaj.org/article/1ea6564c411849c2a858bd817e30910b
Autor:
Yi Xiong, Jiawen Chen, Wei Liang, Kun Li, Yingqi Huang, Jingwen Song, Baoyu Zhang, Xiusheng Qiu, Dongbo Qiu, Qi Zhang, Yunfei Qin
Publikováno v:
Journal of Translational Medicine, Vol 22, Iss 1, Pp 1-16 (2024)
Abstract Background Liver surgery during the perioperative period often leads to a significant complication known as hepatic ischemia-reperfusion (I/R) injury. Hepatic I/R injury is linked to the innate immune response. The cGAS-STING pathway trigger
Externí odkaz:
https://doaj.org/article/036a65c91ca34544a116b3ba95110ba0
Autor:
ZHANG Xiangxin, LI Wen
Publikováno v:
Jichu yixue yu linchuang, Vol 44, Iss 6, Pp 877-881 (2024)
In case of hepatic ischemia-reperfusion injury (HIRI), mitophagy is induced by multiple pathways such as PINK1/Parkin and mitophagy receptor, which is closely related to mitochondrial dynamic related protein. Mitophagy is a double-edged sword. Modera
Externí odkaz:
https://doaj.org/article/bfb844eafda54c42b8e1f2e698f81e9e
Publikováno v:
Molecular Biomedicine, Vol 5, Iss 1, Pp 1-17 (2024)
Abstract Hepatic ischemia–reperfusion injury (HIRI) is a critical pathophysiological process during liver transplantation (LT). Multiple genes and signal pathways are dysregulated during HIRI. This study aims to identify genes as potential therapeu
Externí odkaz:
https://doaj.org/article/3ebd386c312c4a66add634bc85c6e4e3
Publikováno v:
Molecular Medicine, Vol 30, Iss 1, Pp 1-14 (2024)
Abstract Background Programmed cell death is an important mechanism for the development of hepatic ischemia and reperfusion (IR) injury, and multiple novel forms of programmed cell death are involved in the pathological process of hepatic IR. ERRFI1
Externí odkaz:
https://doaj.org/article/4511074bd11c4c1892009c23b54c4e9f
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-13 (2024)
Abstract 6-Gingerol, the main bioactive compound of ginger, has antioxidant, anti-inflammatory, anti-cancer and neuroprotective effects. However, it is unclear whether 6-Gingerol has protective effects against hepatic ischemia/reperfusion (I/R) injur
Externí odkaz:
https://doaj.org/article/b2095ab35f3b453b98fb348024ec64b3
Publikováno v:
BMC Anesthesiology, Vol 24, Iss 1, Pp 1-13 (2024)
Abstract Background Animal experiments have confirmed that remote ischemic preconditioning (RIPC) can reduce hepatic ischemia-reperfusion injuries (HIRIs), significantly improving early tissue perfusion and oxygenation of the residual liver after res
Externí odkaz:
https://doaj.org/article/139e214b10324d59a41607b42bb8b055
Autor:
Leiyi Zhang, Xiaoxiang Gong, Juan Tan, Rongsen Zhang, Mingxia Li, Cong Liu, Chenhao Wu, Xiaojing Li
Publikováno v:
Biology Direct, Vol 19, Iss 1, Pp 1-13 (2024)
Abstract Background This study seeks to investigate the impacts of Lactobacillus reuteri (L. reuteri) on hepatic ischemia-reperfusion (I/R) injury and uncover the mechanisms involved. Methods Mice in the I/R groups were orally administered low and hi
Externí odkaz:
https://doaj.org/article/ff0395ea685f4264a1ce1c6185885db6