Zobrazeno 1 - 10
of 3 178
pro vyhledávání: '"heparan sulfate proteoglycan"'
Autor:
Adrian Najer
Publikováno v:
Smart Medicine, Vol 3, Iss 2, Pp n/a-n/a (2024)
Abstract Global health faces an immense burden from infectious diseases caused by viruses and intracellular protozoan parasites such as the coronavirus disease (COVID‐19) and malaria, respectively. These pathogens propagate through the infection of
Externí odkaz:
https://doaj.org/article/2c8a810b24cf4a70b3560b21844fa0e8
Publikováno v:
Microorganisms, Vol 12, Iss 9, p 1776 (2024)
Hepatitis B virus (HBV) infection remains a major health threat with limited treatment options. One of various new antiviral strategies is based on a fusion of Staphylococcus aureus nuclease (SN) with the capsid-forming HBV core protein (HBc), termed
Externí odkaz:
https://doaj.org/article/8062dc1761924874a3646ad76707d6e8
Publikováno v:
Biomedicines, Vol 11, Iss 11, p 2981 (2023)
Salivary pleomorphic adenoma is histopathologically characterized by its colorful stroma with myxoid, chondroid, and hyaline appearances, due to enhanced biosynthesis of extracellular matrix (ECM) molecules and poor vascularity. Thus, pleomorphic ade
Externí odkaz:
https://doaj.org/article/14cd5d4f2fd94de7a3a93f1e38e8e83c
Publikováno v:
Frontiers in Pediatrics, Vol 11 (2023)
BackgroundBiliary atresia (BA) is a life-threatening disorder, which is characterized by the obliteration of biliary tracts. Heparan sulfate proteoglycans (HSPGs) are important regulators in liver diseases. Whether HSPGs participate in the developmen
Externí odkaz:
https://doaj.org/article/d10687e8d05d43988261140e3475c42b
Autor:
Shannon Faris, Weihua Jin, James Gibson, Anqesha Murray, Nathan Smith, Peng He, Fuming Zhang, Robert Linhardt, Chunyu Wang
Publikováno v:
Frontiers in Molecular Biosciences, Vol 9 (2022)
Tauopathies are neurodegenerative diseases characterized by intracellular abnormal tau deposits in the brain. Tau aggregates can propagate from one neuron to another in a prion-like manner, mediated by the interaction between tau and cell surface hep
Externí odkaz:
https://doaj.org/article/ddabf0a388b34184bb8cd48c812bf969
Publikováno v:
Matrix Biology Plus, Vol 16, Iss , Pp 100121- (2022)
The glycocalyx attached to the apical surface of vascular endothelial cells is a rich network of proteoglycans, glycosaminoglycans, and glycoproteins with instrumental roles in vascular homeostasis. Given their molecular complexity and ability to int
Externí odkaz:
https://doaj.org/article/471aa09327b74e69b0988efda436d01f
Akademický článek
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Akademický článek
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Publikováno v:
Biomedicines, Vol 11, Iss 8, p 2257 (2023)
Despite its widespread existence, there are relatively few drugs that can inhibit the progression of osteoarthritis (OA). Syndecan-4 (SDC4) is a transmembrane heparan sulfate proteoglycan that modulates cellular interactions with the extracellular ma
Externí odkaz:
https://doaj.org/article/7bdff567c9c34ecc998a831c6b85e94c
Publikováno v:
JOR Spine, Vol 5, Iss 2, Pp n/a-n/a (2022)
Abstract Background Daily physiologic loading causes fluctuations in hydration of the intervertebral disc (IVD); thus, the embedded cells experience cyclic alterations to their osmotic environment. These osmotic fluctuations have been described as a
Externí odkaz:
https://doaj.org/article/8323b99d882b4c38bb477eeae539867a