Zobrazeno 1 - 10
of 1 637
pro vyhledávání: '"heme-oxygenase 1"'
Autor:
Ru Li, Riqing Wei, Chenxin Liu, Keying Zhang, Sixiao He, Zhifeng Liu, Junhao Huang, Youyong Tang, Qiyuan An, Ligen Lin, Lishe Gan, Liying Zhao, Xiaoming Zou, Fudi Wang, Yuan Ping, Qiang Ma
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 14, Iss 9, Pp 3983-4000 (2024)
With the escalating prevalence of global heat waves, heat stroke has become a prominent health concern, leading to substantial liver damage. Unlike other forms of liver injury, heat stroke-induced damage is characterized by heat cytotoxicity and heig
Externí odkaz:
https://doaj.org/article/e3af16ae0e584d9cb825283e36a58ea7
Publikováno v:
International Journal of Ophthalmology, Vol 17, Iss 9, Pp 1606-1613 (2024)
AIM: To determine whether etomidate (ET) has a protective effect on retinal ganglion cells (RGCs) injured with hydrogen peroxide (H2O2) and to explore the potential mechanism underlying the antioxidative stress effect of ET. METHODS: Cultured RGCs we
Externí odkaz:
https://doaj.org/article/0c4319b6e8cf46199b758e6fcbdd29ce
Autor:
Loredana Salerno, Antonietta Notaro, Valeria Consoli, Federica Affranchi, Valeria Pittalà, Valeria Sorrenti, Luca Vanella, Michela Giuliano, Sebastiano Intagliata
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 39, Iss 1 (2024)
AbstractColon cancer remains a clinical challenge in industrialised countries. Its treatment with 5-Flurouracil (5-FU) develops many side effects and resistance. Thus, several strategies have been undertaken so far, including the use of drug cocktail
Externí odkaz:
https://doaj.org/article/7cbdfd4d092d43a08cfd45bb07e543c4
Publikováno v:
陆军军医大学学报, Vol 46, Iss 11, Pp 1194-1205 (2024)
Objective To detect the expression profile of heme oxygenase-1 (HO-1) during the process of wound repair in radiation-wound combined injury (R-W-CI), and evaluate its wound healing improving effects of R-W-CI by HO-1 knockdown with siRNA. Methods A t
Externí odkaz:
https://doaj.org/article/aa18f4ec8c024cd6868cdd8cab60c5ad
Publikováno v:
Journal of Ovarian Research, Vol 17, Iss 1, Pp 1-14 (2024)
Abstract Abnormal granulosa cell (GC) death contributes to cyclophosphamide (CTX) induced primary ovarian insufficiency (POI). To investigate the contribution of GCs to POI, gene profiles of GCs exposed to CTX were assessed using RNA-Seq and bioinfor
Externí odkaz:
https://doaj.org/article/d223e088df8e4562a77a3d2004d5bb6a
Publikováno v:
Baghdad Science Journal, Vol 21, Iss 7 (2024)
Heme oxygenase-1(HO-1) is an enzyme that catalyzes and breaks down heme molecules into biliverdin, free iron, bilirubin, and carbon monoxide. This study aims to investigate the levels and role of (HO-1) in obese patients against oxidative stress and
Externí odkaz:
https://doaj.org/article/54befdd3e4b84c39b9662a461dabf501
Publikováno v:
Neural Regeneration Research, Vol 19, Iss 9, Pp 2050-2056 (2024)
[INLINE:1] Previous studies have shown that Biochanin A, a flavonoid compound with estrogenic effects, can serve as a neuroprotective agent in the context of cerebral ischemia/reperfusion injury; however, its effect on spinal cord injury is still unc
Externí odkaz:
https://doaj.org/article/2cbfdc66adb3451d9661c2c6033c99bf
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
BackgroundPolygonatum sibiricum (PS) is a traditional Chinese medicine (TCM) first recorded in Mingyi Bielu. The book documents that PS can nourish five internal organs, be taken for a long time, relax the body and prolong lifespan. Presently, PS is
Externí odkaz:
https://doaj.org/article/aff74264ef3447bd84e938261b6119f6
Autor:
Beixian Zhou, Linxin Wang, Sushan Yang, Yueyun Liang, Yuehan Zhang, Xuanyu Liu, Xiping Pan, Jing Li
Publikováno v:
MedComm, Vol 5, Iss 4, Pp n/a-n/a (2024)
Abstract Pyrogallol, a natural polyphenol compound (1,2,3‐trihydroxybenzene), has shown efficacy in the therapeutic treatment of disorders associated with inflammation. Nevertheless, the mechanisms underlying the protective properties of pyrogallol
Externí odkaz:
https://doaj.org/article/681327dbaf5a448dadeff43838a090d0
Autor:
Ignacio Martínez-Martel, Xue Bai, Rebecca Kordikowski, Christie R. A. Leite-Panissi, Olga Pol
Publikováno v:
Antioxidants, Vol 13, Iss 7, p 856 (2024)
Chemotherapy-provoked peripheral neuropathy and its associated affective disorders are important adverse effects in cancer patients, and its treatment is not completely resolved. A recent study reveals a positive interaction between molecular hydroge
Externí odkaz:
https://doaj.org/article/3909f7eab284432ca8b71815060ef404