Zobrazeno 1 - 10
of 119
pro vyhledávání: '"hematopoietic syndrome"'
Autor:
Haiwei Liang, Yanxiao Ao, Wenjing Li, Kaini Liang, Baixue Tang, Junyang Li, Jianwei Wang, Xiaoyu Zhu, Yanan Du
Publikováno v:
Bioactive Materials, Vol 22, Iss , Pp 453-465 (2023)
Hematopoietic syndrome of acute radiation syndrome (h-ARS) is an acute illness resulted from the damage of bone marrow (BM) microenvironment after exposure to radiation. Currently, the clinical management of h-ARS is limited to medication-assisted tr
Externí odkaz:
https://doaj.org/article/e55563fbe99e4a84822c77fc0314c832
Akademický článek
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Autor:
Sweta Sanguri, Damodar Gupta
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
Total body irradiation (TBI) results in critical injuries in a dose dependent manner that primarily damages highly proliferating tissues including hematopoietic stem cells (HSCs) and intestinal crypt stem cells etc. This may result in hematopoietic s
Externí odkaz:
https://doaj.org/article/5b9347202c2e4d60bfe13380b7c5c391
Autor:
Juliann G. Kiang, Ayodele O. Olabisi
Publikováno v:
Cell & Bioscience, Vol 9, Iss 1, Pp 1-15 (2019)
Abstract The range of radiation threats we face today includes everything from individual radiation exposures to mass casualties resulting from a terrorist incident, and many of these exposure scenarios include the likelihood of additional traumatic
Externí odkaz:
https://doaj.org/article/f7329842cece4fd08c395e9b9724c4bc
Autor:
Akinori Morita, Bing Wang, Kaoru Tanaka, Takanori Katsube, Masahiro Murakami, Takashi Shimokawa, Yuichi Nishiyama, Shintaro Ochi, Hidetoshi Satoh, Mitsuru Nenoi, Shin Aoki
Publikováno v:
Frontiers in Public Health, Vol 8 (2020)
Radiation damage to normal tissues is one of the most serious concerns in radiation therapy, and the tolerance dose of the normal tissues limits the therapeutic dose to the patients. p53 is well known as a transcription factor closely associated with
Externí odkaz:
https://doaj.org/article/088a697ee94041e89325b14a23b3a05d
Akademický článek
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Autor:
Yuichi Nishiyama, Akinori Morita, Shogo Tatsuta, Misaki Kanamaru, Masahiro Sakaue, Kenta Ueda, Manami Shono, Rie Fujita, Bing Wang, Yoshio Hosoi, Shin Aoki, Takeshi Sugai
Publikováno v:
Genes, Vol 12, Iss 10, p 1514 (2021)
Flavonoids are a subclass of polyphenols which are attractive, due to possessing various physiological activities, including a radioprotective effect. Tumor suppressor p53 is a primary regulator in the radiation response and is involved in the pathog
Externí odkaz:
https://doaj.org/article/546d66bd1dfa4630b3d0fe8c436c3071
Akademický článek
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Autor:
Bing Wang, Masahide Tominaga, Hidetoshi Satoh, Dwi Ramadhani, Kaoru Tanaka, Akinori Morita, Takuma Sakai, Megumi Sasatani, Hitoshi Ikushima, Mitsuru Nenoi, Shin Aoki, Junji Ueno, Yuichi Nishiyama, Shintaro Ochi
Publikováno v:
International Journal of Radiation Biology. 97(9):1241-1251
Purpose: Our previous study indicated that sodium orthovanadate (vanadate), a strong inhibitor of p53, effectively suppressed the lethality from the hematopoietic (HP) and gastrointestinal (GI) syndromes after 12 Gy total-body irradiation (TBI) in mi
Publikováno v:
Frontiers in Immunology, Vol 8 (2017)
The inflamed bone marrow niche shortly after total body irradiation (TBI) is known to contribute to loss of hematopoietic stem cells in terms of their number and function. In this study, autologous bone marrow transfer (AL-BMT) was evaluated as a str
Externí odkaz:
https://doaj.org/article/2b32949389364d23aebe3eefcd82073f