Zobrazeno 1 - 10
of 869
pro vyhledávání: '"hematopoietic stem progenitor cells"'
Autor:
Mingfang Xiong, Yanyu Xiu, Juan Long, Xiao Zhao, Qianqian Wang, Haoyu Yang, Hang Yu, Lihong Bian, Yan Ju, Hongyu Yin, Qingxiang Hou, Fei Liang, Nan Liu, Fudong Chen, Ruiwen Fan, Yuying Sun, Yang Zeng
Publikováno v:
Stem Cell Research & Therapy, Vol 15, Iss 1, Pp 1-22 (2024)
Abstract Background Hematopoietic stem progenitor cells (HSPCs) undergo phenotypical and functional changes during their emergence and development. Although the molecular programs governing the development of human hematopoietic stem cells (HSCs) hav
Externí odkaz:
https://doaj.org/article/dd09f771b52c41e4a1ea7887c9835507
Autor:
Jyotika Srivastava, Kavita Kundal, Bhuvnesh Rai, Pragati Saxena, Shobhita Katiyar, Naresh Tripathy, Sanjeev Yadav, Ruchi Gupta, Rahul Kumar, Soniya Nityanand, Chandra Prakash Chaturvedi
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-14 (2024)
Abstract Recently, we have reported that extracellular vesicles (EVs) from the bone marrow mesenchymal stromal cells (BM-MSC) of aplastic anemia (AA) patients inhibit hematopoietic stem and progenitor cell (HSPC) proliferative and colony-forming abil
Externí odkaz:
https://doaj.org/article/1e3494ed58314a2fa5796ada0af1c237
Publikováno v:
Stem Cell Research & Therapy, Vol 15, Iss 1, Pp 1-11 (2024)
Abstract Background Hematopoiesis in mammal is a complex and highly regulated process in which hematopoietic stem cells (HSCs) give rise to all types of differentiated blood cells. Previous studies have shown that hairy and enhancer of split (HES) re
Externí odkaz:
https://doaj.org/article/e5b058c6e3ac4b01a8dddddebb672062
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Methyltransferase-like 3(METTL3), recognized as the primary N6-methyladenosine methyltransferase, influences cellular functions such as proliferation, migration, invasion, differentiation, and fate determination by regulating gene expression post-tra
Externí odkaz:
https://doaj.org/article/848f3dd25576455b8aa8d9845fd11b26
Autor:
Mónica del Rey González, Sohini Chakraborty, Jesús María Hernández-Sánchez, María Diez Campelo, Christopher Y. Park, Jesús María Hernández Rivas
Publikováno v:
Frontiers in Oncology, Vol 14 (2024)
Treatment with the hypomethylating agent 5-azacytidine (AZA) increases survival in high-risk (HR) myelodysplastic syndrome (MDS) patients, but predicting patient response and overall survival remains challenging. To address these issues, we analyzed
Externí odkaz:
https://doaj.org/article/c7fb6c7685b74917942b55da558c1fcc
Autor:
Keyi Chen, Yunqiao Li, Xumin Wu, Xuan Tang, Bowen Zhang, Tao Fan, Lijuan He, Xuetao Pei, Yanhua Li
Publikováno v:
Stem Cell Research & Therapy, Vol 15, Iss 1, Pp 1-12 (2024)
Abstract Background Human hematopoietic organoids have a wide application value for modeling human bone marrow diseases, such as acute hematopoietic radiation injury. However, the manufacturing of human hematopoietic organoids is an unaddressed chall
Externí odkaz:
https://doaj.org/article/a1e645bb87aa4f338b9d5171c47ddf03
Publikováno v:
Frontiers in Hematology, Vol 3 (2024)
Externí odkaz:
https://doaj.org/article/7af5e264af784055a43fa030950ec69c
Autor:
Jingwen Qiu, Jing Wu, Wenwen Chen, Yu Ruan, Jingning Mao, Shue Li, Xuan Tang, Lei Zhao, Shengbing Li, Ke Li, Dongfang Liu, Yaqian Duan
Publikováno v:
Stem Cell Research & Therapy, Vol 15, Iss 1, Pp 1-17 (2024)
Abstract Background Nucleotide-binding oligomerization domain-containing protein 1 (NOD1) plays a pivotal role in inducing metabolic inflammation in diabetes. Additionally, the NOD1 ligand disrupts the equilibrium of bone marrow-derived hematopoietic
Externí odkaz:
https://doaj.org/article/792c70f65dec4f9380d206ed4037e35b
Autor:
Xiaofen Liu, Wenjuan Zhang, Changbin Jing, Lei Gao, Cong Fu, Chunguang Ren, Yimei Hao, Mengye Cao, Ke Ma, Weijun Pan, Dantong Li
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 12 (2024)
Externí odkaz:
https://doaj.org/article/f121e9feeb32442ea1455215487211e0
Autor:
Yang-Xi Hu, Qing Jing
Publikováno v:
Cell Regeneration, Vol 12, Iss 1, Pp 1-14 (2023)
Abstract Myelopoiesis is the process in which the mature myeloid cells, including monocytes/macrophages and granulocytes, are developed. Irregular myelopoiesis may cause and deteriorate a variety of hematopoietic malignancies such as leukemia. Myeloi
Externí odkaz:
https://doaj.org/article/acba87a5cdd84dad9302adb0211ddbb0