Zobrazeno 1 - 10
of 293
pro vyhledávání: '"hematopoietic niche"'
Publikováno v:
Frontiers in Molecular Biosciences, Vol 11 (2024)
Hematopoietic stem cells (HSC) reside within specialized microenvironments that undergo dynamic changes throughout development and aging to support HSC function. However, the evolving cell-cell communication networks within these niches remain largel
Externí odkaz:
https://doaj.org/article/bdec449952104fa792965378b7a7ab96
Publikováno v:
Pharmaceutical Biology, Vol 61, Iss 1, Pp 768-778 (2023)
AbstractContext 5-Fluorouracil (5-FU)-injured stromal cells may cause chronic bone marrow suppression; however, the underlying mechanism remains unclear. Angelica sinensis polysaccharide (ASP), the main biologically active ingredient of the Chinese h
Externí odkaz:
https://doaj.org/article/ef028622609f4e97bb7d252b23b306f1
Autor:
Helen C. O’Neill, Hong Kiat Lim
Publikováno v:
Frontiers in Physiology, Vol 14 (2023)
In bone marrow, the niche which supports hematopoiesis and nurtures hematopoietic stem cells (HSCs) contains perivascular reticular cells representing a subset of skeletal stem/progenitor cells (SSPCs). These stromal cells which provide the niche are
Externí odkaz:
https://doaj.org/article/9be303faa20f41f6aa4b2f0f18a405a1
Autor:
Giulia Pozzi, Cecilia Carubbi, Giacomo Maria Cerreto, Chiara Scacchi, Samuele Cortellazzi, Marco Vitale, Elena Masselli
Publikováno v:
Biomedicines, Vol 11, Iss 9, p 2462 (2023)
Dysregulated inflammatory signaling is a key feature of myeloproliferative neoplasms (MPNs), most notably of myelofibrosis (MF). Indeed, MF is considered the prototype of onco-inflammatory hematologic cancers. While increased levels of circulatory an
Externí odkaz:
https://doaj.org/article/8215330ebf8a4d33a55c780d9e61e1eb
Autor:
Michela Bruschi, Tania Vanzolini, Neety Sahu, Alessandra Balduini, Mauro Magnani, Alessandra Fraternale
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 10 (2022)
Hematopoietic stem cells (HSCs) reside in a subzone of the bone marrow (BM) defined as the hematopoietic niche where, via the interplay of differentiation and self-renewal, they can give rise to immune and blood cells. Artificial hematopoietic niches
Externí odkaz:
https://doaj.org/article/b6e525faf1f64a838b227f9d9ecca692
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Externí odkaz:
https://doaj.org/article/1b0620f984804341b0acb4a60d58abdc
Autor:
Dorothée Girard, Frédéric Torossian, Estelle Oberlin, Kylie A. Alexander, Jules Gueguen, Hsu-Wen Tseng, François Genêt, Jean-Jacques Lataillade, Marjorie Salga, Jean-Pierre Levesque, Marie-Caroline Le Bousse-Kerdilès, Sébastien Banzet
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Hematopoiesis and bone interact in various developmental and pathological processes. Neurogenic heterotopic ossifications (NHO) are the formation of ectopic hematopoietic bones in peri-articular muscles that develop following severe lesions of the ce
Externí odkaz:
https://doaj.org/article/6c105ec4195a4c97a81d7b9517fb7e90
Autor:
Corina A. Ghebes, Jess Morhayim, Marion Kleijer, Merve Koroglu, Stefan J. Erkeland, Remco Hoogenboezem, Eric Bindels, Floris P. J. van Alphen, Maartje van den Biggelaar, Martijn A. Nolte, Bram C. J. van der Eerden, Eric Braakman, Carlijn Voermans, Jeroen van de Peppel
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 9 (2021)
Recently, we and others have illustrated that extracellular vesicles (EVs) have the potential to support hematopoietic stem and progenitor cell (HSPC) expansion; however, the mechanism and processes responsible for the intercellular communication by
Externí odkaz:
https://doaj.org/article/f63912cbb2284cb18223a36ce8f0da38
Autor:
Niida, Shumpei, Kondo, Takako, Hiratsuka, Sachie, Hayashi, Shin-Ichi, Amizuka, Norio, Noda, Tetsuo, Ikeda, Kyoji, Shibuya, Masabumi, Hanafusa, Hidesaburo
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America, 2005 Sep . 102(39), 14016-14021.
Externí odkaz:
https://www.jstor.org/stable/3376820
Autor:
Briseño, Carlos G., Gargaro, Marco, Durai, Vivek, Davidson, Jesse T., Theisen, Derek J., Anderson, David A., Novack, Deborah V., Murphy, Theresa L., Murphy, Kenneth M.
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America, 2017 Apr 01. 114(15), 3957-3962.
Externí odkaz:
https://www.jstor.org/stable/26480845