Zobrazeno 1 - 10
of 3 462
pro vyhledávání: '"helper T cells"'
Publikováno v:
Molecular Medicine, Vol 30, Iss 1, Pp 1-12 (2024)
Abstract A new population of peripheral helper T (Tph) cells has been identified and contributed to various autoimmune diseases. Tph cells can secrete interleukin-21 (IL-21), interferon (IFN) and C-X-C motif chemokine ligand 13 (CXCL13) to moderate r
Externí odkaz:
https://doaj.org/article/3a895359dac24c36b070bb9864f9d4f0
Autor:
Astrid Imbert, Pierre-Jean Gavlovsky, Jean-Paul Judor, Edouard Bardou-Jacquet, Laure Elkrief, Adrien Lannes, Christine Silvain, Mathieu Schnee, Florence Tanne, Caroline Chevalier, Fabienne Vavasseur, Marion Khaldi, Sophie Brouard, Jean-François Mosnier, Jérôme Gournay, Sophie Conchon, Amédée Renand
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-11 (2024)
Abstract Relapse after immunosuppression (IS) treatment withdrawal is frequent in patients with Autoimmune Hepatitis (AIH), and non-invasive biomarkers predictive of this risk are lacking. We assessed the frequency of circulating T cell subsets as po
Externí odkaz:
https://doaj.org/article/f249c91e0f4045b49ea2ccb0dae5c652
Autor:
Tipanan Khunsri, Pongsakorn Thawornpan, Pachara Tianpothong, Thanitta Suangtamai, Pintip Ngamjanyaporn, Chaniya Leepiyasakulchai, Kittikorn Wangriatisak, Prapaporn Pisitkun, Patchanee Chootong
Publikováno v:
Arthritis Research & Therapy, Vol 26, Iss 1, Pp 1-11 (2024)
Abstract Background Systemic lupus erythematosus (SLE) is the quintessential autoimmune disease, as it is characterized by hyperactivity of CD4+ T cells and subsequently drives lupus pathology. Follicular helper T (TFH) cells play an important role i
Externí odkaz:
https://doaj.org/article/85226088e98b420487aab866d40c4bb5
Autor:
Ryosuke Tsurui, Hisakata Yamada, Takahiro Natori, Motoki Yoshimura, Yukio Akasaki, Shinya Kawahara, Hiroaki Niiro, Yuya Kunisaki, Yasuharu Nakashima
Publikováno v:
Journal of Translational Autoimmunity, Vol 9, Iss , Pp 100258- (2024)
Objective: Dysregulated T cell homeostasis has long been implicated in the pathogenesis of rheumatoid arthritis (RA), in the joint of which peripheral helper T (Tph) cells accumulate and form ectopic lymphoid organs. We examined whether homeostatic s
Externí odkaz:
https://doaj.org/article/b9b5c0d603754a958d3c101acc003610
Autor:
Nadeeya Mad-adam, Sirinapa Dokduang, Siriporn Taraporn, Thidarath Rattanaburee, Jirakrit Saetang, Aekkaraj Nualla-ong, Somchai Sriwiriyajan, Jasadee Kaewsrichan, Yaowapa Sukpondma, Poonsit Hiransai, Potchanapond Graidist
Publikováno v:
Food and Agricultural Immunology, Vol 35, Iss 1 (2024)
Our study aimed to evaluate tumour retardation effects of low-piperine fractional Piper nigrum extract (PFPE or LP-PE) related to enhancement of immune response. Results showed that PFPE at doses of 50 (low), 100 (intermediated) and 150 (high) mg/kg
Externí odkaz:
https://doaj.org/article/ea059c8620d94717ad35ed96e74a62d8
Publikováno v:
Dermatopathology, Vol 11, Iss 3, Pp 218-229 (2024)
IgG4-RD is a multisystem fibroinflammatory disease characterized by the infiltration of tissues by IgG4 plasma cells. Combined skin and biliary tract involvement in IgG4-RD has not been described. We present perhaps the most comprehensive analysis of
Externí odkaz:
https://doaj.org/article/3e4cd441164545fe82a7a5304fa01f02
Publikováno v:
Chinese Journal of Lung Cancer, Vol 27, Iss 7, Pp 550-558 (2024)
Non-small cell lung cancer (NSCLC) is a prevalent and aggressive global malignancy. Conventional surgical treatments, radiotherapy, chemotherapy, and targeted therapies often fall short in halting disease progression due to inherent limitations, resu
Externí odkaz:
https://doaj.org/article/20f5328109a944dfb57b9887624feebf
Autor:
Ruomeng Pei, Jia Wang, Peifeng He, Qi Yu, Shengxiao Zhang, Gaoxiang Shi, Geliang Liu, Xiaofeng Li
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
IntroductionIn patients with rheumatoid arthritis (RA), the increased risk of concomitant type 2 diabetes mellitus (T2D) is an important contributor to increased mortality and decreased quality of life; however, the mechanisms and pathogenetic factor
Externí odkaz:
https://doaj.org/article/488e3893948f45bb932432e7881025f5
Autor:
Jayaum S. Booth, Rekha R. Rapaka, Monica A. McArthur, Stephanie Fresnay, Thomas C. Darton, Christoph J. Blohmke, Claire Jones, Claire S. Waddington, Myron M. Levine, Andrew J. Pollard, Marcelo B. Sztein
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Despite decades of intense research, our understanding of the correlates of protection against Salmonella Typhi (S. Typhi) infection and disease remains incomplete. T follicular helper cells (TFH), an important link between cellular and humoral immun
Externí odkaz:
https://doaj.org/article/2584ad89ecfd40c2bb661c8fb10159e5
Autor:
Stéphane Rodriguez, Mehdi Alizadeh, Claire Lamaison, Alexis Saintamand, Céline Monvoisin, Rachel Jean, Laurent Deleurme, Jose Ignacio Martin-Subero, Céline Pangault, Michel Cogné, Patricia Amé-Thomas, Karin Tarte
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Externí odkaz:
https://doaj.org/article/858fed6b609e452cb08824915c58ded1