Výsledky vyhledávání - "heart-drug effects"

Akademický článek

Epidemiology, Pathophysiology, and Management of Native Atrioventricular Valve Regurgitation in Heart Failure Patients

Autor: Anne-Céline Martin, Marie-Cécile Bories, Noemie Tence, Pierre Baudinaud, Louis Pechmajou, Tania Puscas, Eloi Marijon, Paul Achouh, Nicole Karam

Publikováno v: Frontiers in Cardiovascular Medicine, Vol 8 (2021)

Atrioventricular regurgitation is frequent in the setting of heart failure. It is due to atrial and ventricular remodelling, as well as rhythmic disturbances and loss of synchrony. Once atrioventricular regurgitation develops, it can aggravate the un

Externí odkaz: https://doaj.org/article/78ea2028d38d41f7b4f442e724292ec4

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The antibiotic doxycycline impairs cardiac mitochondrial and contractile function

Autor: Diederik W. D. Kuster, Michel van Weeghel, Vida Alizadeh Tazehkandi, Luciënne Baks-Te Bulte, Gustav J. Strijkers, Bram F. Coolen, Ntsiki M. Held, Bianca J. J. M. Brundel, Riekelt H. Houtkooper, Mariah R R Daal, Marit Wiersma, Rob C. I. Wüst

Publikováno v: Wüst, R C I, Coolen, B F, Held, N M, Daal, M R R, Tazehkandi, V A, Baks-Te Bulte, L, Wiersma, M, Kuster, D W D, Brundel, B J J M, van Weeghel, M, Strijkers, G J & Houtkooper, R H 2021, ' The antibiotic doxycycline impairs cardiac mitochondrial and contractile function ', International Journal of Molecular Sciences, vol. 22, no. 8, 4100 . https://doi.org/10.3390/ijms22084100
International journal of molecular sciences, 22(8):4100. Multidisciplinary Digital Publishing Institute (MDPI)
International Journal of Molecular Sciences, 22(8):4100, 1-19. Multidisciplinary Digital Publishing Institute (MDPI)
International Journal of Molecular Sciences
Volume 22
Issue 8
Wüst, R C I, Coolen, B F, Held, N M, Daal, M R R, Tazehkandi, V A, Baks-Te Bulte, L, Wiersma, M, Kuster, D W D, Brundel, B J J M, van Weeghel, M, Strijkers, G J & Houtkooper, R H 2021, ' The antibiotic doxycycline impairs cardiac mitochondrial and contractile function ', International Journal of Molecular Sciences, vol. 22, no. 8, 4100, pp. 1-19 . https://doi.org/10.3390/ijms22084100
International Journal of Molecular Sciences, 22(8):4100. Multidisciplinary Digital Publishing Institute (MDPI)
International Journal of Molecular Sciences, Vol 22, Iss 4100, p 4100 (2021)

Tetracycline antibiotics act by inhibiting bacterial protein translation. Given the bacterial ancestry of mitochondria, we tested the hypothesis that doxycycline—which belongs to the tetracycline class—reduces mitochondrial function, and results

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba143ec8e34cf744f53dea11e2bd5101
https://doi.org/10.3390/ijms22084100

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Subchronic exposure to titanium dioxide nanoparticles modifies cardiac structure and performance in spontaneously hypertensive rats

Publikováno v: Particle and Fibre Toxicology, Vol 16, Iss 1, Pp 1-18 (2019)
Particle and Fibre Toxicology
Rossi, S, Savi, M, Mazzola, M, Pinelli, S, Alinovi, R, Gennaccaro, L, Pagliaro, A, Meraviglia, V, Galetti, M, Lozano-Garcia, O, Rossini, A, Frati, C, Falco, A, Quaini, F, Bocchi, L, Stilli, D, Lucas, S, Goldoni, M, Macchi, E, Mutti, A & Miragoli, M 2019, ' Subchronic exposure to titanium dioxide nanoparticles modifies cardiac structure and performance in spontaneously hypertensive rats ', Particle and Fibre Toxicology, vol. 16, no. 1, 25, pp. 25 . https://doi.org/10.1186/s12989-019-0311-7

Background Non-communicable diseases, intended as the results of a combination of inherited, environmental and biological factors, kill 40 million people each year, equivalent to roughly 70% of all premature deaths globally. The possibility that manu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::385db94142b41acc6b5336509220a282
http://link.springer.com/article/10.1186/s12989-019-0311-7

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Kounis Syndrome: Case Report in Goiânia/BR

Autor: Pereira, Marília, Vieitas, Gabriela Lima, Freitas, Anna Ilona Hunkar, Hunkar, Karoly Gyula Olivas

Publikováno v: International Journal of Cardiovascular Sciences, Issue: ahead, Published: 23 JUN 2021
International Journal of Cardiovascular Sciences v.34 n.5 suppl.1 2021
International Journal of Cardiovascular Sciences
Sociedade Brasileira de Cardiologia (SBC)
instacron:SBC
International Journal of Cardiovascular Sciences, Volume: 34, Issue: 5 Supplement 1, Pages: 135-138, Published: 17 JUN 2021

22-year-old male patient with no heart disease, who was given an ambulatory medication with analgesics due to an acute renal crisis. After the drug administration, the patient presented dyspnea, cyanosis, and hemoptysis. There was suspicion of anaphy

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::85c7a24045b598699fddab82721dcc9e
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S2359-56472021005007202&lng=en&tlng=en

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Assessment of acute and chronic toxicity of doxorubicin in human induced pluripotent stem cell-derived cardiomyocytes

Autor: Taina Palosaari, Jochem Louisse, Pilar Prieto, Francesca Pistollato, Rob C. I. Wüst, Susanne Bremer, Manuela Barilari, Peter Macko

Publikováno v: Toxicology in Vitro, 42, 182-190. Elsevier Limited
Louisse, J, Wüst, R C I, Pistollato, F, Palosaari, T, Barilari, M, Macko, P, Bremer, S & Prieto, P 2017, ' Assessment of acute and chronic toxicity of doxorubicin in human induced pluripotent stem cell-derived cardiomyocytes ', Toxicology in Vitro, vol. 42, pp. 182-190 . https://doi.org/10.1016/j.tiv.2017.04.023
Toxicology in vitro, 42, 182-190. Elsevier Limited

The present study assesses acute and chronic toxicity of doxorubicin in human induced pluripotent stem cell derived cardiomyocytes (hiPSC-CMs), with the aim to obtain in vitro biomarkers that can be used as readouts to predict in vivo cardiotoxicity.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12badb039aa75c4161220a991025aafc
http://www.scopus.com/inward/record.url?scp=85018349514&partnerID=8YFLogxK

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Effects of PDE-5 Inhibition on the Cardiopulmonary System After 2 or 4 Weeks of Chronic Hypoxia

Autor: Giuseppina Milano, Antonio F. Corno, Coline Nydegger, Ludwig K. von Segesser, Maurice Beghetti, Michele Samaja

Publikováno v: Cardiovascular Drugs and Therapy
Cardiovascular drugs and therapy, vol. 33, no. 4, pp. 407-414
Cardiovascular Drugs and Therapy, Vol. 33, No 4 (2019) pp. 407-414

Purpose In pulmonary hypertension (PH), hypoxia represents both an outcome and a cause of exacerbation. We addressed the question whether hypoxia adaptation might affect the mechanisms underlying PH alleviation through phosphodiesterase-5 (PDE5) inhi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ed473909655b9dee0f381932d76ce1e
https://pubmed.ncbi.nlm.nih.gov/31264002

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Akademický článek

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Akademický článek

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A key role of TRPC channels in the regulation of electromechanical activity of the developing heart

Autor: Eric Raddatz, Elodie Robin, Jessica Sabourin

Publikováno v: Cardiovascular research
Cardiovascular Research, vol. 92, no. 2, pp. 226-236

Aims It is well established that dysfunction of voltage-dependent ion channels results in arrhythmias and conduction disturbances in the foetal and adult heart. However, the involvement of voltage-insensitive cationic TRPC (transient receptor potenti

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a23ad1b15cd4d5724aefe5cddae683a
https://doi.org/10.1093/cvr/cvr167

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