Zobrazeno 1 - 10
of 670
pro vyhledávání: '"hdac9"'
Publikováno v:
Current Issues in Molecular Biology, Vol 46, Iss 6, Pp 5178-5193 (2024)
Histone deacetylase 9 (HDAC9) is known to be upregulated in various cancers. Cancer-associated antigens (CAGEs) are cancer/testis antigens that play an important role in anti-cancer drug resistance. This study aimed to investigate the relationship be
Externí odkaz:
https://doaj.org/article/9dd815432e864cd188e5daf6888066f8
Publikováno v:
Pharmacogenomics and Personalized Medicine, Vol Volume 17, Pp 215-224 (2024)
Lili Yu,1 Youwei Zhao2 1Department of Neurology, Haikou People’s Hospital, Haikou, 570208, People’s Republic of China; 2Qingyun College, Hainan University, Haikou, 570228, People’s Republic of ChinaCorrespondence: Youwei Zhao, Email 992639@hain
Externí odkaz:
https://doaj.org/article/f1f644ebaa8241098dd0f76381bcb684
Autor:
Zhenfeng Chen, Bingqi Lin, Xiaodan Yao, Jie Weng, Jinlian Liu, Qi He, Ke Song, Chuyu Zhou, Zirui Zuo, Xiaoxia Huang, Zhuanhua Liu, Qiaobing Huang, Qiulin Xu, Xiaohua Guo
Publikováno v:
Cell Communication and Signaling, Vol 22, Iss 1, Pp 1-22 (2024)
Abstract Background Diabetic angiogenesis is closely associated with disabilities and death caused by diabetic microvascular complications. Advanced glycation end products (AGEs) are abnormally accumulated in diabetic patients and are a key pathogeni
Externí odkaz:
https://doaj.org/article/39986a6a01c2437c888ae0c46e26452b
Publikováno v:
Renal Failure, Vol 46, Iss 2 (2024)
Vascular calcification, a common complication of chronic kidney disease (CKD), remains an unmet therapeutic challenge. The trans-differentiation of vascular smooth muscle cells (VSMCs) into osteoblast-like cells is crucial in the pathogenesis of vasc
Externí odkaz:
https://doaj.org/article/f3451ce40539465dae39550a9ff9abd8
Publikováno v:
Cellular & Molecular Biology Letters, Vol 28, Iss 1, Pp 1-24 (2023)
Abstract Background Intervertebral disc degeneration (IVDD) is the major cause of low-back pain. Histone deacetylase 9 (HDAC9) was dramatically decreased in the degenerative nucleus pulposus (NP) samples of patients with intervertebral disc degenerat
Externí odkaz:
https://doaj.org/article/cad0f8e390b54ecd8a81b68c21d7a64b
Autor:
Qing Ling, Yutong Zhou, Yu Qian, Jiejing Qian, Yi Zhang, Jinghan Wang, Yanan Zhu, Yile Zhou, Juying Wei, Chunmei Yang, Jie Sun, Wenjuan Yu, Jie Jin, Xiang Zhang
Publikováno v:
Biomarker Research, Vol 11, Iss 1, Pp 1-5 (2023)
Abstract KMT2A-rearranged acute myeloid leukemia (KMT2Ar-AML) is an aggressive subtype of AML with poor response and prognosis. KMT2Ar-AML has been demonstrated to be sensitive to BCL2 inhibitor venetoclax (VEN), but these patients are unable to bene
Externí odkaz:
https://doaj.org/article/fe5effd15134428ebe2d2d07aff7ef4f
Publikováno v:
Vaccines, Vol 12, Iss 6, p 626 (2024)
Background: This study aimed to explore how genetic variations in individuals impact neutralization activity post-mRNA vaccination, recognizing the critical role vaccination plays in curbing COVID-19 spread and the necessity of ensuring vaccine effic
Externí odkaz:
https://doaj.org/article/c7817c9e06014f67b9090e3306715281
Publikováno v:
Biomolecules & Biomedicine, Vol 24, Iss 1 (2024)
Intracranial aneurysm (IA) is one of the most challenging cerebrovascular lesions for clinicians. The aim of this study was to investigate the abnormal expression and role of histone deacetylase 9 (HDAC9) in IA-associated injury of vascular endotheli
Externí odkaz:
https://doaj.org/article/a3bb4eefa2b8420eb957523ad821f457
Autor:
Min Liu, Yang Zhang, Ping Zhan, Wenjuan Sun, Chuanqiao Dong, Xiaohan Liu, Yujie Yang, Xiaojie Wang, Yusheng Xie, Chengjiang Gao, Huili Hu, Benkang Shi, Ziying Wang, Chun Guo, Fan Yi
Publikováno v:
Pharmacological Research, Vol 198, Iss , Pp 107009- (2023)
Although hyperhomocysteinemia (hHcys) has been recognized as an important independent risk factor in the progression of end-stage renal disease and the development of cardiovascular complications related to end-stage renal disease, the mechanisms tri
Externí odkaz:
https://doaj.org/article/b75d1c61ff964de882682ddef23b59b2
Publikováno v:
Translational Neuroscience, Vol 14, Iss 1, Pp 15-39 (2023)
MiRNAs play a key role in ischemic stroke (IS). Although miR-101-3p can participate in multiple disease processes, its role and mechanism in IS are not clear. The aim of the present study was to observe the effect of miR-101-3p activation on IS in yo
Externí odkaz:
https://doaj.org/article/9a651e5696a844769096923b58f89897