Zobrazeno 1 - 10
of 41
pro vyhledávání: '"hair cell protection"'
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 18 (2024)
BackgroundA number of drugs are toxic to the cochlear sensory cells known as hair cells (HCs), resulting in hearing loss. Treatment with survival-promoting growth factors, antioxidants, and inhibitors of cell death pathways or proteinases have been s
Externí odkaz:
https://doaj.org/article/8e0472819a384f6ba20f33ba0505afa5
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 17 (2023)
The cochlea is the sensory organ in the periphery, and hair cells are its main sensory cells. The development and survival of hair cells are highly controlled processes. When cells face intracellular and environmental stimuli, epigenetic regulation c
Externí odkaz:
https://doaj.org/article/89d908ba9fc44f119c33785d748842cd
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Autor:
Pengjun Li, Dan Bing, Sumei Wang, Jin Chen, Zhihui Du, Yanbo Sun, Fan Qi, Yingmiao Zhang, Hanqi Chu
Publikováno v:
Frontiers in Neuroscience, Vol 13 (2019)
A lack of sleep is linked with a range of inner ear diseases, including hearing loss and tinnitus. Here, we used a mouse model to investigate the effects of sleep deprivation (SD) on noise vulnerability, and explored the mechanisms that might be invo
Externí odkaz:
https://doaj.org/article/375203588143430184fe9739596e6f8d
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 11 (2017)
Inner ear hair cell death leads to sensorineural hearing loss and can be a direct consequence of aminoglycoside antibiotic treatment. Aminoglycosides such as gentamicin are effective therapy for serious Gram-negative bacterial infections such as some
Externí odkaz:
https://doaj.org/article/7bdad23ec08548a3a2d3b3a4382e9af9
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 9 (2015)
Loss of sensory hair cells from exposure to certain licit drugs (e.g., aminoglycoside antibiotics, platinum-based chemotherapy agents) can result in permanent hearing loss. Here we ask if allosteric activation of the hepatocyte growth factor (HGF) ca
Externí odkaz:
https://doaj.org/article/5a260fd38277453d8ee7a6fa963495a0
Autor:
Lingna Guo, Suhua Sha, Weijia Kong, Zuhong He, Ling Lu, Dingding Liu, Yongze Liu, Yilai Shu, Mingliang Tang, Xiaoqiong Ding, Xia Gao, Han Zhou, Dong Liu, Xiaoli Zhang, Renjie Chai, Qiaojun Fang, Huawei Li
Publikováno v:
Autophagy
Aminoglycosides are toxic to sensory hair cells (HCs). Macroautophagy/autophagy is an essential and highly conserved self-digestion pathway that plays important roles in the maintenance of cellular function and viability under stress. However, the ro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7eeea91316adf73b331493957d242059
http://europepmc.org/articles/PMC5788479
http://europepmc.org/articles/PMC5788479
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Autor:
Josef G. Trapani, Alexander J. Ordoobadi, Matthew Kruger, Allison B. Coffin, Robert Boney, Thomas F. Sommers
Publikováno v:
Frontiers in Cellular Neuroscience
Frontiers in Cellular Neuroscience, Vol 10 (2016)
Frontiers in Cellular Neuroscience, Vol 10 (2016)
Moderate to severe hearing loss affects 360 million people worldwide and most often results from damage to sensory hair cells. Hair cell damage can result from aging, genetic mutations, excess noise exposure, and certain medications including aminogl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff14f9b0996d9d41e484b71d7498631e
http://europepmc.org/articles/PMC4811916
http://europepmc.org/articles/PMC4811916