Zobrazeno 1 - 10
of 34 452
pro vyhledávání: '"gwas"'
Publikováno v:
Animal Bioscience, Vol 37, Iss 12, Pp 2054-2065 (2024)
Objective The improvement of carcass traits is essential for the Hanwoo industry because of the Hanwoo grade determination system, and genome-wide association study (GWAS) analysis is an instrumental tool for identifying the genetic factors that impa
Externí odkaz:
https://doaj.org/article/dd8bda7b3275474c8a5bd65dce8550a8
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-17 (2024)
Abstract The GRAMD genes are involved in maintaining cholesterol homeostasis, apoptosis, cancer and production traits in livestock. A lipid-binding GRAM domain is implicated in lipid transport and metabolism. The functions of GRAMD proteins remain in
Externí odkaz:
https://doaj.org/article/c20bd54d960f446e9823ee3bc50fa091
Autor:
Poppy Diah Palupi, Chun-Yu Wei, Wan-Hsuan Chou, Min-Rou Lin, Yu-Jui Yvonne Wan, Wei-Chiao Chang
Publikováno v:
Cell & Bioscience, Vol 14, Iss 1, Pp 1-10 (2024)
Abstract Background The fibrosis-4 (FIB-4) index is a non-invasive method to assess the severity of liver fibrosis. The development of liver fibrosis is influenced by genetic predisposition and dietary factors. However, the modulating effect of dieta
Externí odkaz:
https://doaj.org/article/27a9fbe0da1148b8adc10d52719994b4
Autor:
Chong Zhang, Yonghang Zhang, Cong Liu, Lingyu Wang, Yani Dong, Donglei Sun, Haishen Wen, Kaiqiang Zhang, Xin Qi, Yun Li
Publikováno v:
Animal Research and One Health, Vol 2, Iss 4, Pp 400-416 (2024)
Abstract Spotted sea bass (Lateolabrax maculatus) is a species of significant economic importance in aquaculture. However, genetic degeneration, such as declining growth performance, has severely impeded industry development, necessitating urgent gen
Externí odkaz:
https://doaj.org/article/bd468cfe5df24ac6b96013b622de8041
Deciphering the tissue-specific functional effect of Alzheimer risk SNPs with deep genome annotation
Autor:
Pradeep Varathan Pugalenthi, Bing He, Linhui Xie, Kwangsik Nho, Andrew J. Saykin, Jingwen Yan
Publikováno v:
BioData Mining, Vol 17, Iss 1, Pp 1-13 (2024)
Abstract Alzheimer’s disease (AD) is a highly heritable brain dementia, along with substantial failure of cognitive function. Large-scale genome-wide association studies (GWASs) have led to a set of SNPs significantly associated with AD and related
Externí odkaz:
https://doaj.org/article/08d95b1169a6436d9516f10b1c912f11
Autor:
Mohammad Shahbazi, Heather E. Wheeler, Gregory T. Armstrong, Robert D. Frisina, Lois B. Travis, M. Eileen Dolan
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-13 (2024)
Abstract Tinnitus is a common sensorineural complication that can occur de novo or after cancer treatments involving cisplatin or radiotherapy. Considering the heterogeneous etiology and pathophysiology of tinnitus, the extent to which shared genetic
Externí odkaz:
https://doaj.org/article/288b8c672e924134bc31b6107b3bd81e
Autor:
Chuankun Wang, Yaqi Zeng, Jianwen Wang, Tongliang Wang, Xueyan Li, Zhehong Shen, Jun Meng, Xinkui Yao
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-15 (2024)
Abstract Racing performance traits are the main indicators for evaluating the performance and value of sport horses. The aim of this study was to identify the key genes for racing performance traits in Yili horses by performing a genome-wide associat
Externí odkaz:
https://doaj.org/article/1225c5b0b8ff4334bc405f79ee79b19d
Autor:
Chenguang Zhang, Huifeng Liu, Xingwei Jiang, Zhihong Zhang, Xinfeng Hou, Yue Wang, Dangdang Wang, Zongjun Li, Yangchun Cao, Shengru Wu, Sharon A. Huws, Junhu Yao
Publikováno v:
Microbiome, Vol 12, Iss 1, Pp 1-21 (2024)
Abstract Background Despite the growing number of studies investigating the connection between host genetics and the rumen microbiota, there remains a dearth of systematic research exploring the composition, function, and metabolic traits of highly h
Externí odkaz:
https://doaj.org/article/1731ff8c5e2948f0aa8c96191104df01
Autor:
Johanna Samola Winnberg, Litika Vermani, Wen Liu, Veronika Soller, Jessada Thutkawkorapin, Mats Lindblad, Annika Lindblom
Publikováno v:
Hereditary Cancer in Clinical Practice, Vol 22, Iss 1, Pp 1-8 (2024)
Abstract Background A complex inheritance has been suggested in families with colorectal-, gastric- and prostate cancer. Therefore, we conducted a genome-wide association study (GWAS) in colorectal cancer patients, who’s relatives had prostate-, an
Externí odkaz:
https://doaj.org/article/d2d0507c542a4318972cba875b2631f9
Autor:
Jiayan Wu, Ruijie Liu, Yuxin Xie, Shuqi Zhao, Mengyuan Yan, Nan Sun, Yihua Zhan, Feifei Li, Shuxun Yu, Zhen Feng, Libei Li
Publikováno v:
BMC Genomics, Vol 25, Iss 1, Pp 1-12 (2024)
Abstract Transcription Factors (TFs) are key regulators of how plants grow and develop. Among the diverse TF families, the Glabrous-enhancer binding protein (GeBP) family plays a key role in trichome initiation and leaf development. The specific role
Externí odkaz:
https://doaj.org/article/0c20e78c65b04e60a09514a30467e621