Zobrazeno 1 - 10
of 189
pro vyhledávání: '"guodong hu"'
Autor:
Chunmei Nong, Zhenzhen Wu, Chan Yang, Wei Xu, Linyi Luo, Jianping Zhou, Lihan Shen, Yinghua Chen, Yaoqin Yuan, Guodong Hu
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 14 (2024)
IntroductionSARS-CoV-2 infection drove senescent cells and the senescence-associated phenotypes were reported playing roles in disease progression, which contributes to severe COVID-19 and related sequelae. Cdc42 is involved in the regulation of cell
Externí odkaz:
https://doaj.org/article/dc60435767b54e3383a44b74c591d4d2
Autor:
Guodong Hu, Huan-Xiang Zhou
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-10 (2023)
Abstract The SAM/SAH riboswitch binds S-adenosylmethionine (SAM) and S-adenosylhomocysteine (SAH) with similar affinities. Mg2+ is generally known to stabilize RNA structures by neutralizing phosphates, but how it contributes to ligand binding and co
Externí odkaz:
https://doaj.org/article/b8fc36a38f60470783e4c5b09c23615a
Publikováno v:
Molecules, Vol 29, Iss 10, p 2317 (2024)
The phosphorylation of different sites produces a significant effect on the conformational dynamics of KRAS. Gaussian accelerated molecular dynamics (GaMD) simulations were combined with deep learning (DL) to explore the molecular mechanism of the ph
Externí odkaz:
https://doaj.org/article/96b4c924ac9d4a32a29148bd38493e6b
Aggregation-Induced Emission-Active Photosensitizer-Mediated Photodynamic Therapy for Anti-Psoriasis
Autor:
Ping Zhu, Zhaoji Wu, Zhilu Yang, Tingting Tang, Yunhui Liao, Wen Zhao, Ying Huang, Tao Chen, Junjie Li, Chunmei Nong, Zhenzhen Wu, Guodong Hu, Yanshan Liu, Yinghua Chen
Publikováno v:
Research, Vol 7 (2024)
Hyperproliferative keratinocytes and subcutaneous inflammation contribute to the characteristic symptoms of psoriasis, including erythema, scales, or scaly plaques on the skin. These symptoms significantly affect patients’ quality of life and cause
Externí odkaz:
https://doaj.org/article/0eec336217b149a1a1ed42a21697e609
Publikováno v:
Frontiers in Plant Science, Vol 14 (2024)
IntroductionContinuous identification and application of novel resistance genes against stripe rust are of great importance for wheat breeding. Wild emmer wheat, Triticum dicoccoides, has adapted to a broad range of environments and is a valuable gen
Externí odkaz:
https://doaj.org/article/70044fff9b044b469328017457835cb5
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
Hypoglycemia has multiple causes, but the most common is a complication of insulin treatment. In addition to insulin therapy, tumors such as insulinomas of pancreatic origin and extrapancreatic tumors causing paraneoplastic syndromes should also be c
Externí odkaz:
https://doaj.org/article/8f7d5eea06b54900b62f98c714ec6b90
Publikováno v:
Molecules, Vol 29, Iss 3, p 645 (2024)
The HRAS protein is considered a critical target for drug development in cancers. It is vital for effective drug development to understand the effects of mutations on the binding of GTP and GDP to HRAS. We conducted Gaussian accelerated molecular dyn
Externí odkaz:
https://doaj.org/article/43f043b8bd16491a96441ded83357fa5
Publikováno v:
Foods, Vol 12, Iss 23, p 4363 (2023)
The accumulation of pesticide residues poses a significant threat to the health of people and the surrounding ecological systems. However, traditional methods are not only costly but require expertise in analysis. An electrochemiluminescence (ECL) ap
Externí odkaz:
https://doaj.org/article/f791baedbd754303af5247fef66e2545
Autor:
Ping Wang, Guodong Hu, Wen Zhao, Juan Du, Menghan You, Mengying Xv, Hong Yang, Min Zhang, Fang Yan, Mianbo Huang, Xueer Wang, Lin Zhang, Yinghua Chen
Publikováno v:
Journal of Nanobiotechnology, Vol 20, Iss 1, Pp 1-23 (2022)
Abstract Background Increasing interest in the hazardous properties of zinc oxide nanoparticles (ZnO NPs), commonly used as ultraviolet filters in sunscreen, has driven efforts to study the percutaneous application of ZnO NPs to diseased skin; howeve
Externí odkaz:
https://doaj.org/article/856903830cee422a8efdf8c908c50b4a
Publikováno v:
Jixie chuandong, Vol 45, Pp 132-138 (2021)
Aiming at the low stroke times motion characteristics badly of beam pumping units，a reversing mechanism for gear guide-rod pumping units is analyzed. The reversing mechanism is mainly composed of a long rod incomplete gear，a rack moving frame，a
Externí odkaz:
https://doaj.org/article/bd14746a9a614bbb9ccdc736d751fe3b