Zobrazeno 1 - 10
of 4 183
pro vyhledávání: '"gstm1"'
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 43, Iss 1, Pp 1-18 (2024)
Abstract Background Blacks/African American (BAA) patients diagnosed with head and neck squamous cell carcinoma (HNSCC) have worse survival outcomes than White patients. However, the mechanisms underlying racial disparities in HNSCC have not been tho
Externí odkaz:
https://doaj.org/article/2cd138a31c8d40ac99820dee8f89fef9
Autor:
Peipei Li, Duopin Li, Yanfang Lu, Shaokang Pan, Fei Cheng, Shen Li, Xiaonan Zhang, Jinling Huo, Dongwei Liu, Zhangsuo Liu
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
IntroductionCisplatin is a widely used chemotherapeutic agent prescribed to treat solid tumors. However, its clinical application is limited because of cisplatin- induced nephrotoxicity. A known complication of cisplatin is acute kidney injury (AKI).
Externí odkaz:
https://doaj.org/article/c60f7cd6aba04615871989fa65420dfc
Autor:
Tiantian Xu, Yan Pan, Qinchao Ding, Feiwei Cao, Kaixin Chang, Jiannan Qiu, Hui Zhuge, Liuyi Hao, Haibin Wei, Caijuan Si, Xiaobing Dou, Songtao Li
Publikováno v:
Cellular & Molecular Biology Letters, Vol 29, Iss 1, Pp 1-19 (2024)
Abstract Background and aims Epidemiological evidence suggests that the phenotype of glutathione S-transferase mu 1 (GSTM1), a hepatic high-expressed phase II detoxification enzyme, is closely associated with the incidence of alcohol-related liver di
Externí odkaz:
https://doaj.org/article/79adc6271fe9423e93a742435617c078
Autor:
Harsh Yadav, Depanshi Pandit, Sidhartha Singh, Parul Sharma, Kranti Garg, Nidhi Girdhar, Karan Sharma, Vishal Chopra, Siddharth Chopra, Siddharth Sharma
Publikováno v:
Experimental Physiology, Vol 109, Iss 2, Pp 302-311 (2024)
Abstract Chronic obstructive pulmonary disease (COPD) is commonly characterized by shortness of breath, coughing or expectoration. Smoking is the leading cause of COPD development, but only a small percentage of smokers develop symptoms, implying a g
Externí odkaz:
https://doaj.org/article/389859770e23452bb1fc50b4de0c5646
Autor:
Saadat Mostafa
Publikováno v:
Scripta Medica, Vol 55, Iss 1, Pp 97-105 (2024)
Oxidative stress is involved in the development of systemic lupus erythematosus (SLE). It is well known that activity of the glutathione S-transferase superfamily has a protective effect against oxidative stress. Several studies have investigated the
Externí odkaz:
https://doaj.org/article/803da2f138dd4b50a539871d7b7e3268
Autor:
Viktorija Ulanova, Agnija Kivrane, Anda Viksna, Leonora Pahirko, Lauma Freimane, Darja Sadovska, Iveta Ozere, Andra Cirule, Eduards Sevostjanovs, Solveiga Grinberga, Dace Bandere, Renate Ranka
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
Objectives: Isoniazid is a key drug in the chemotherapy of tuberculosis (TB), however, interindividual variability in pharmacokinetic parameters and drug plasma levels may affect drug responses including drug induced hepatotoxicity. The current study
Externí odkaz:
https://doaj.org/article/c4c2861429c14d29a0cb8b08315e9f4c
Autor:
Jie Peng, Pei Ma, Xueqin Wu, Tianrong Yang, Yuting Hu, Ying Xu, Shuang Li, Hang Zhang, Hongzhou Liu
Publikováno v:
Heliyon, Vol 9, Iss 11, Pp e21183- (2023)
Background: GSTM1 deletion was reported to be associated with CKD progression in cohort studies. However, the results of case‒control studies were conflicting. The association between GST genes and CKD progression needs to be studied in China. Ther
Externí odkaz:
https://doaj.org/article/c731b3851095469781d4f8609f43ab91
Publikováno v:
Analiz Riska Zdorovʹû, Iss 1, Pp 146-159 (2023)
Chloroform accumulation in the body and the increase in its steady-state concentrations in blood of exposed people have been established to be associated with polymorphisms of enzyme genes in a genotype involved in metabolism of water disinfection by
Externí odkaz:
https://doaj.org/article/bbfa553c25fc4f31b928a6aa516bb095
Akademický článek
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Publikováno v:
Journal of Pharmacy and Bioallied Sciences, Vol 15, Iss 4, Pp 180-189 (2023)
Background/Objective/Methods: Glutathione-S-transferase Mu1 (GSTM1) and glutathione peroxidase 1 (GPX1) are known antioxidant enzymes that help protect cells from the oxidative damage that occurs from smoking. This study explored the correlation betw
Externí odkaz:
https://doaj.org/article/043aff0906bd44b792a7f568aa61cf8b