Zobrazeno 1 - 10
of 1 304
pro vyhledávání: '"growth hormone (gh)"'
Publikováno v:
Heliyon, Vol 10, Iss 18, Pp e36397- (2024)
Purpose: Liver-expressed antimicrobial peptide-2 (LEAP2) is identified as an endogenous antagonist and inverse agonist of the growth hormone secretagogue receptor type 1a (GHSR1a), its effect on the GHSR1a is contrary to the role of GHRELIN. Growth h
Externí odkaz:
https://doaj.org/article/926b1ca22ee84087a8ddcad153908c78
Autor:
Simona F. Madeo, Luca Zagaroli, Sara Vandelli, Valeria Calcaterra, Antonino Crinò, Luisa De Sanctis, Maria Felicia Faienza, Danilo Fintini, Laura Guazzarotti, Maria Rosaria Licenziati, Enza Mozzillo, Roberta Pajno, Emanuela Scarano, Maria E. Street, Malgorzata Wasniewska, Sarah Bocchini, Carmen Bucolo, Raffaele Buganza, Mariangela Chiarito, Domenico Corica, Francesca Di Candia, Roberta Francavilla, Nadia Fratangeli, Nicola Improda, Letteria A. Morabito, Chiara Mozzato, Virginia Rossi, Concetta Schiavariello, Giovanni Farello, Lorenzo Iughetti, Vincenzo Salpietro, Alessandro Salvatoni, Mara Giordano, Graziano Grugni, Maurizio Delvecchio
Publikováno v:
Frontiers in Endocrinology, Vol 15 (2024)
Prader-Willi syndrome (PWS) is a complex genetic disorder caused by three different types of molecular genetic abnormalities. The most common defect is a deletion on the paternal 15q11-q13 chromosome, which is seen in about 60% of individuals. The ne
Externí odkaz:
https://doaj.org/article/c1738baa0e3049e2aabf886903f94dc3
Autor:
Caiyan Mo, Liyong Zhong
Publikováno v:
Endocrine Journal, Vol 70, Iss 11, Pp 1051-1060 (2023)
Long-term stimulation of thyroid follicular epithelium by high growth hormone (GH) and insulin-like growth factor-1 (IGF-1) in patients with acromegaly can lead to thyroid dysfunction, goiter, thyroid nodules, and even thyroid cancer and thyroid-asso
Externí odkaz:
https://doaj.org/article/3a5679f7cbf545d3b756e7eb43d0f3c7
Autor:
Reetobrata Basu, Prateek Kulkarni, Deborah Swegan, Silvana Duran-Ortiz, Arshad Ahmad, Lydia J. Caggiano, Emily Davis, Christopher Walsh, Edward Brenya, Adeel Koshal, Rich Brody, Uday Sandbhor, Sebastian J. C. M. M. Neggers, John J. Kopchick
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 13, p 7438 (2024)
Chemotherapy treatment against pancreatic ductal adenocarcinoma (PDAC) is thwarted by tumoral activation of multiple therapy resistance pathways. The growth hormone (GH)–GH receptor (GHR) pair is a covert driver of multimodal therapy resistance in
Externí odkaz:
https://doaj.org/article/1a3f8bb5ee834aec859077d1d8d528f8
Autor:
Kohei Oguni, Koichiro Yamamoto, Yasuhiro Nakano, Yoshiaki Soejima, Atsuhito Suyama, Ryosuke Takase, Miho Yasuda, Kou Hasegawa, Fumio Otsuka
Publikováno v:
Frontiers in Endocrinology, Vol 15 (2024)
Serum levels of growth hormone (GH) and insulin-like growth factor (IGF)-I are crucial in the diagnosis and management of GH-related diseases. However, these levels are affected by nutritional and metabolic status. To elucidate the correlations betwe
Externí odkaz:
https://doaj.org/article/0ae43a8ace1d44819a1102d107540ae5
Autor:
Kotaro HORIGUCHI, Yuto TSUTSUI, Ken FUJIWARA, Takehiro TSUKADA, Takashi NAKAKURA, Saishu YOSHIDA, Rumi HASEGAWA, Shu TAKIGAMI
Publikováno v:
The Journal of Reproduction and Development, Vol 69, Iss 6, Pp 308-316 (2023)
The adenohypophysis is comprised of the anterior and intermediate lobes (AL and IL, respectively). Cluster of differentiation 9 (CD9)- and sex-determining region Y-box 2 (SOX2)-positive cells are stem/progenitor hormone-producing cells in the AL. The
Externí odkaz:
https://doaj.org/article/73ac818fbf154adbaf049fcff1543ab1
Autor:
Haim Werner, Zvi Laron
Publikováno v:
Frontiers in Endocrinology, Vol 14 (2023)
The growth hormone (GH)-insulin-like growth factor-1 (IGF1) signaling pathway emerged in recent years as a key determinant of aging and longevity. Disruption of this network in different animal species, including flies, nematodes and mouse, was consi
Externí odkaz:
https://doaj.org/article/87ae8de496ce4aa290e5650019afed85
Autor:
Guiliang Peng, Chuanhong Guo, Yangfan Lv, Dandan Li, Ling Zhou, Rufei Shen, Yong Chen, Xin Zheng, Zheng Sun, Hongting Zheng, Min Long
Publikováno v:
BMC Endocrine Disorders, Vol 22, Iss 1, Pp 1-8 (2022)
Abstract Background Thyrotropin-secreting pituitary neuroendocrine tumors (PitNETs) are rare pituitary adenomas that are occasionally accompanied by hypersecretion of other anterior pituitary hormones, such as growth hormone (GH) and prolactin (PRL).
Externí odkaz:
https://doaj.org/article/1ecbad1b8d7641ce9b6ef23a066105df
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