Zobrazeno 1 - 10
of 669
pro vyhledávání: '"growth factor signaling"'
Autor:
Mingming Zhao, Yukimasa Taniguchi, Chisei Shimono, Tatsuya Jonouchi, Yushen Cheng, Yasuhiro Shimizu, Minas Nalbandian, Takuya Yamamoto, Masato Nakagawa, Kiyotoshi Sekiguchi, Hidetoshi Sakurai
Publikováno v:
Advanced Science, Vol 11, Iss 26, Pp n/a-n/a (2024)
Abstract Human‐induced pluripotent stem cells (hiPSCs) have great therapeutic potential. The cell source differentiated from hiPSCs requires xeno‐free and robust methods for lineage‐specific differentiation. Here, a system is described for diff
Externí odkaz:
https://doaj.org/article/40e931d2849540e8aada2992c2202ab6
Publikováno v:
Biology Open, Vol 12, Iss 8 (2023)
Externí odkaz:
https://doaj.org/article/5965d1e04fe446b68bb3434cb984b449
Akademický článek
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Autor:
Dhiman Sankar Pal, Yiyan Lin, Huiwang Zhan, Tatsat Banerjee, Jonathan Kuhn, Stephenie Providence, Peter N. Devreotes
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 11 (2023)
In this article, we provide detailed protocols on using optogenetic dimerizers to acutely perturb activities of guanine nucleotide exchange factors (GEFs) specific to Ras, Rac or Rho small GTPases of the migratory networks in various mammalian and am
Externí odkaz:
https://doaj.org/article/2febf12d98354c6a8e7028fa1064e820
Publikováno v:
Cellular & Molecular Biology Letters, Vol 27, Iss 1, Pp 1-19 (2022)
Abstract Background ΔNp63 overexpression is a common event in squamous cell carcinoma (SCC) that contributes to tumorigenesis, making ΔNp63 a potential target for therapy. Methods We created inducible TP63-shRNA cells to study the effects of p63-de
Externí odkaz:
https://doaj.org/article/0b0cb76926f74bbd9889be741a13cd99
Akademický článek
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Publikováno v:
Cells, Vol 12, Iss 18, p 2265 (2023)
Integrins were originally identified as receptors for extracellular matrix (ECM) and cell-surface molecules (e.g., VCAM-1 and ICAM-1). Later, we discovered that many soluble growth factors/cytokines bind to integrins and play a critical role in growt
Externí odkaz:
https://doaj.org/article/9e7e8bf784504209badecf26d7c1fba9
Autor:
Mehrshad Sadria, Anita T. Layton
Publikováno v:
Cell Communication and Signaling, Vol 19, Iss 1, Pp 1-17 (2021)
Abstract Background Cells adapt their metabolism and activities in response to signals from their surroundings, and this ability is essential for their survival in the face of perturbations. In tissues a deficit of these mechanisms is commonly associ
Externí odkaz:
https://doaj.org/article/e6babc6e51a2401cb9cf1d22147f689f
Autor:
Ya Peng, Xiangsheng Li, Huowang Liu, Xiaowen Deng, Chang She, Chenxi Liu, Xinxing Wang, An Liu
Publikováno v:
Nanoscale Research Letters, Vol 15, Iss 1, Pp 1-17 (2020)
Abstract Objectives Nasopharyngeal carcinoma (NPC) is a type of nasopharyngeal disease with high metastasis and invasion properties. Tumor-associated alternative activated (M2) macrophages are evidenced to connect with NPC. Based on this, this study
Externí odkaz:
https://doaj.org/article/2e264318d3c44facacf77f5bc38bb4b1
Autor:
Min Song, Stacey D. Finley
Publikováno v:
Cell Communication and Signaling, Vol 18, Iss 1, Pp 1-19 (2020)
Abstract Background Angiogenesis plays an important role in the survival of tissues, as blood vessels provide oxygen and nutrients required by the resident cells. Thus, targeting angiogenesis is a prominent strategy in many different settings, includ
Externí odkaz:
https://doaj.org/article/e5ba9e6d5a7c42698f96aeb699b9050d