Zobrazeno 1 - 10
of 2 276
pro vyhledávání: '"graves' orbitopathy"'
Autor:
Michele Marinò, Giovanna Rotondo Dottore, Francesca Menconi, Simone Comi, Giada Cosentino, Roberto Rocchi, Francesco Latrofa, Michele Figus, Ferruccio Santini
Publikováno v:
European Thyroid Journal, Vol 13, Iss 6, Pp 1-9 (2024)
Objectives: The pathogenesis of Graves’ orbitopathy (GO) remains to be fully elucidated. Here, we reviewed the role of genetics and epigenetics. Design: We conducted a PubMed search with the following keywords: GO, thyroid eye disease; or Graves’
Externí odkaz:
https://doaj.org/article/163927fd511840aeabbbefbdc5ccd71e
Publikováno v:
Acta Medica Bulgarica, Vol 51, Iss s2, Pp 165-170 (2024)
Graves' disease (GD) is an autoimmune disease that affects the thyroid and the eyes. Graves' ophthalmopathy (GO), an autoimmune disease, usually appears 18 months after GD diagnosis. Clinical activity and disease severity determine the strategy, with
Externí odkaz:
https://doaj.org/article/c581223563924ce3afb4555494b31807
Publikováno v:
International Journal of General Medicine, Vol Volume 17, Pp 3719-3731 (2024)
Cai Yang, Jiafeng Xiao, Zibei Xu, Zehong Wang Department of Laboratory Medicine, Medical Center Hospital of Qionglai City, Chengdu, Sichuan, 611530, People’s Republic of ChinaCorrespondence: Zehong Wang, Department of Laboratory Medicine, Medical C
Externí odkaz:
https://doaj.org/article/63b713023b2d4bbd9053f3594240c3bc
Publikováno v:
BMC Ophthalmology, Vol 24, Iss 1, Pp 1-10 (2024)
Abstract Purpose The primary objective of this study was to identify predictive factors linked to the normalization of thyroid-stimulating immunoglobulin (TSI) levels in patients diagnosed with active, moderate-to-severe Graves’ orbitopathy (GO). T
Externí odkaz:
https://doaj.org/article/9ab39ba8e81140b5a1877c4268fa48d3
Autor:
Mohammad Taher Rajabi, Reza Sadeghi, Mohammad Reza Abdol Homayuni, Saharnaz Pezeshgi, Seyedeh Simindokht Hosseini, Mohammad Bagher Rajabi, Sepideh Poshtdar
Publikováno v:
BMC Ophthalmology, Vol 24, Iss 1, Pp 1-13 (2024)
Abstract Purpose To evaluate the evidence for alterations of blood flow, vascular and perfusion densities in the choroid, macula, peripapillary region, and the area surrounding the optic nerve head (ONH) in patients with thyroid-associated ophthalmop
Externí odkaz:
https://doaj.org/article/f59c36c7589046d78695c8a3dfb2a5ae
Publikováno v:
Endocrine Journal, Vol 71, Iss 9, Pp 851-861 (2024)
Interleukin-2-inducible tyrosine kinase (ITK) is a crucial cytoplasmic protein in the T-cell signaling pathway. Here, we aimed to demonstrate the anti-inflammatory effect of the selective IL-2-induced tyrosine kinase inhibitor BMS-509744 (BMS) on Gra
Externí odkaz:
https://doaj.org/article/80faa5db925a424196a053b7296ac10c
Publikováno v:
Frontiers in Ophthalmology, Vol 4 (2024)
Externí odkaz:
https://doaj.org/article/378f25c9b9b243ef92ff5db20f0de3c7
Autor:
Gijsbert J. Hötte, Maaike de Bie, Ronald O.B. de Keizer, P. Martijn Kolijn, Roosmarijn C. Drexhage, Sharon Veenbergen, Marjan A. Versnel, P. Martin van Hagen, Dion Paridaens, Willem A. Dik
Publikováno v:
Frontiers in Endocrinology, Vol 15 (2024)
BackgroundFor the selective detection of thyroid-stimulating hormone receptor antibodies with stimulating properties (thyroid-stimulating immunoglobulins; TSI), a novel and rapid bioassay (Turbo TSI) has been introduced. We evaluate the clinical perf
Externí odkaz:
https://doaj.org/article/b885507448394a0dab78dc9868995ab0
Autor:
Chiaw-Ling Chng, Oi Fah Lai, Lay-Leng Seah, Kai-Ling Yong, Yvonne Hsi-Wei Chung, Rochelle Goh, Che Kang Lim
Publikováno v:
Frontiers in Genetics, Vol 15 (2024)
BackgroundThere are no reliable biomarkers to identify Graves’ disease patients who will develop severe Graves’ orbitopathy (GO). We hypothesize that integrating various omics platforms can enhance our understanding of disease mechanisms and unco
Externí odkaz:
https://doaj.org/article/7b2ae8fc00a94e2c82df4cd15c7298cd
Publikováno v:
Ophthalmology and Therapy, Vol 13, Iss 6, Pp 1499-1511 (2024)
Abstract Introduction Graves’ ophthalmopathy (GO) is an autoimmune inflammatory disorder observed in a substantial proportion of patients with Graves’ disease (GD), with debilitating symptoms of disfiguring, periorbital pain, dry eyes, diplopia,
Externí odkaz:
https://doaj.org/article/1f79e79678cd4d0ebbd265feb05e3d31