Zobrazeno 1 - 10
of 21 551
pro vyhledávání: '"granule cell"'
Autor:
Salvatore Ssemmanda
Publikováno v:
BMC Neurology, Vol 24, Iss 1, Pp 1-4 (2024)
Abstract Background John Cunningham virus related granule cell neuronopathy (JCV-GCN) is a rare manifestation of the reactivation of infection of the cerebellar granule cells by the JCV, mostly in immunocompromised individuals. The “hot cross bun
Externí odkaz:
https://doaj.org/article/10425de0e6db4b5496147b14934289ec
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 18 (2024)
Central arginine vasopressin (AVP) facilitates social recognition and modulates many complex social behaviors in mammals that, in many cases, recognize each other based on olfactory and/or pheromonal signals. AVP neurons are present in the accessory
Externí odkaz:
https://doaj.org/article/6009e0d3cc1a4b208af6d6e0695dfdbd
Loss of Elp1 in cerebellar granule cell progenitors models ataxia phenotype of Familial Dysautonomia
Autor:
Frederik Arnskötter, Patricia Benites Goncalves da Silva, Mackenna E. Schouw, Chiara Lukasch, Luca Bianchini, Laura Sieber, Jesus Garcia-Lopez, Shiekh Tanveer Ahmad, Yiran Li, Hong Lin, Piyush Joshi, Lisa Spänig, Magdalena Radoš, Mykola Roiuk, Mari Sepp, Marc Zuckermann, Paul A. Northcott, Annarita Patrizi, Lena M. Kutscher
Publikováno v:
Neurobiology of Disease, Vol 199, Iss , Pp 106600- (2024)
Familial Dysautonomia (FD) is an autosomal recessive disorder caused by a splice site mutation in the gene ELP1, which disproportionally affects neurons. While classically characterized by deficits in sensory and autonomic neurons, neuronal defects i
Externí odkaz:
https://doaj.org/article/27595f3c5f8c4217868b4b0677549c70
Autor:
Kyoji Ohyama, Hiroshi M. Shinohara, Natsumi Takayama, Rina Ogawa, Shoichiro Omura, Mio Hayashida, Tokiharu Takahashi
Publikováno v:
Frontiers in Neuroscience, Vol 18 (2024)
During the development of the mouse dentate gyrus (DG), granule neuronal progenitors (GNPs) arise from glial fibrillary acidic protein (GFAP)-expressing neural stem cells in the dentate notch. However, the transcriptional regulators that control thei
Externí odkaz:
https://doaj.org/article/4f8707765b8e41678e8c8b21cbbcdd4b
Autor:
Josef Newman, Xiaoying Tong, April Tan, Toni Yeasky, Vanessa Nunes De Paiva, Pietro Presicce, Paranthaman S. Kannan, Kevin Williams, Andreas Damianos, Marione Tamase Newsam, Merline K. Benny, Shu Wu, Karen C. Young, Lisa A. Miller, Suhas G. Kallapur, Claire A. Chougnet, Alan H. Jobe, Roberta Brambilla, Augusto F. Schmidt
Publikováno v:
Journal of Neuroinflammation, Vol 21, Iss 1, Pp 1-19 (2024)
Abstract Background Preterm birth is often associated with chorioamnionitis and leads to increased risk of neurodevelopmental disorders, such as autism. Preterm birth can lead to cerebellar underdevelopment, but the mechanisms of disrupted cerebellar
Externí odkaz:
https://doaj.org/article/4330d26737704358ad8660367418ee35
Akademický článek
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Publikováno v:
Molecular Brain, Vol 16, Iss 1, Pp 1-22 (2023)
Abstract High frequency burst firing is critical in summation of back-propagating action potentials (APs) in dendrites, which may greatly depolarize dendritic membrane potential. The physiological significance of burst firings of hippocampal dentate
Externí odkaz:
https://doaj.org/article/8e622fd781c54a7fac6b5181c45a7817
Autor:
Jerome Clasadonte, Tania Deprez, Gabriel S. Stephens, Georges Mairet-Coello, Pierre-Yves Cortin, Maxime Boutier, Aurore Frey, Jeannie Chin, Marek Rajman
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 16 (2024)
Activity induced transcription factor ΔFosB plays a key role in different CNS disorders including epilepsy, Alzheimer’s disease, and addiction. Recent findings suggest that ΔFosB drives cognitive deficits in epilepsy and together with the emergen
Externí odkaz:
https://doaj.org/article/d2dd9f4f1f4540508a2b8550c0ff6076
Autor:
Eunju Leem, Sehwan Kim, Chanchal Sharma, Youngpyo Nam, Tae Yeon Kim, Minsang Shin, Seok-Geun Lee, Jaekwang Kim, Sang Ryong Kim
Publikováno v:
Biomolecules, Vol 14, Iss 3, p 380 (2024)
Although granule cell dispersion (GCD) in the hippocampus is known to be an important feature associated with epileptic seizures in temporal lobe epilepsy (TLE), the endogenous molecules that regulate GCD are largely unknown. In the present study, we
Externí odkaz:
https://doaj.org/article/1c22e324f30c4b8eab3bf3aafb1308d3
Publikováno v:
Neurobiology of Disease, Vol 187, Iss , Pp 106311- (2023)
Hippocampal oxytocin receptor (OXTR) signaling is crucial for discrimination of social stimuli to guide social recognition, but circuit mechanisms and cell types involved remain incompletely understood. Here, we report a role for OXTR-expressing hila
Externí odkaz:
https://doaj.org/article/f346f313adc94710985b0f5878f9c145