Zobrazeno 1 - 10
of 3 039
pro vyhledávání: '"gnotobiotic"'
Autor:
J. Jacob Parnell, Gaurav Pal, Ayesha Awan, Simina Vintila, Gabriella Houdinet, Christine V. Hawkes, Peter J. Balint-Kurti, Maggie R. Wagner, Manuel Kleiner
Publikováno v:
Phytobiomes Journal, Vol 8, Iss 4, Pp 418-424 (2024)
Studies of plant–microbe interactions using synthetic microbial communities (SynComs) often require the removal of seed-associated microbes by seed sterilization prior to inoculation to provide gnotobiotic growth conditions. Diverse seed sterilizat
Externí odkaz:
https://doaj.org/article/8856ecb00b5d4973a00a79c1fd35a02a
Autor:
Nyblade, Charlotte June
Clostridioides difficile (C. difficile) and human rotavirus (HRV) are leading causes of bacterial and viral gastroenteritis worldwide. Treatment and vaccination options for both pathogens have significant limitations. C. difficile infections are trea
Externí odkaz:
https://hdl.handle.net/10919/121514
Autor:
Aadra P. Bhatt, Jason W. Arnold, Muyiwa Awoniyi, Shan Sun, Verônica Feijoli Santiago, Deniz Coskuner, Pedro Henrique Quintela, Kenneth Walsh, Jamie Xiao, Renay Ngobeni-Nyambi, Brenna Hansen, Ajay S. Gulati, Ian M. Carroll, M. Andrea Azcarate-Peril, Anthony A. Fodor, Jonathan Swann, Luther A. Bartelt
Publikováno v:
Gut Microbes, Vol 16, Iss 1 (2024)
Undernutrition in children commonly disrupts the structure and function of the small intestinal microbial community, leading to enteropathies, compromised metabolic health, and impaired growth and development. The mechanisms by which diet and microbe
Externí odkaz:
https://doaj.org/article/d8139dcd72204cbf9349d5f3a89cfbad
Autor:
Matilde Cescon, Giovanna Gambarotta, Sonia Calabrò, Chiara Cicconetti, Francesca Anselmi, Svenja Kankowski, Luisa Lang, Marijana Basic, Andre Bleich, Silvia Bolsega, Matthias Steglich, Salvatore Oliviero, Stefania Raimondo, Dario Bizzotto, Kirsten Haastert-Talini, Giulia Ronchi
Publikováno v:
Gut Microbes, Vol 16, Iss 1 (2024)
Gut microbiota is responsible for essential functions in human health. Several communication axes between gut microbiota and other organs via neural, endocrine, and immune pathways have been described, and perturbation of gut microbiota composition h
Externí odkaz:
https://doaj.org/article/8f5e1d94adf849aca2091db0dc43a781
Autor:
Yadeliz A. Serrano Matos, Jasmine Cano, Hamna Shafiq, Claire Williams, Julee Sunny, Carrie A. Cowardin
Publikováno v:
Microbiome, Vol 12, Iss 1, Pp 1-16 (2024)
Abstract Background Childhood undernutrition is a major global health challenge with devastating lifelong consequences. Linear growth stunting due to undernutrition has been linked to poor health outcomes, and mothers who experience growth stunting i
Externí odkaz:
https://doaj.org/article/a457a9b445b9409b9df3b5100bde1843
Autor:
Michael Olbrich, Adina-Malin Hartmann, Sven Künzel, Zouhair Aherrahrou, Paul Schilf, John F. Baines, Saleh M. Ibrahim, Misa Hirose
Publikováno v:
Pharmacological Research, Vol 205, Iss , Pp 107231- (2024)
We previously demonstrated that mice carrying natural mtDNA variants of the FVB/NJ strain (m.7778 G>T in the mt-Atp8 gene in mitochondrial complex V), namely C57BL/6 J-mtFVB/NJ (B6-mtFVB), exhibited (i) partial protection from experimental skin infla
Externí odkaz:
https://doaj.org/article/1a81fe206ac04aa69c9a82cb18c3724c
Autor:
Charlotte Nyblade, Lijuan Yuan
Publikováno v:
Viruses, Vol 16, Iss 9, p 1432 (2024)
For nearly twenty years, gnotobiotic (Gn) pigs have been used as a model of human norovirus (HuNoV) infection and disease. Unique in their ability to develop diarrhea and shed virus post oral challenge, Gn pigs have since been used to evaluate the in
Externí odkaz:
https://doaj.org/article/f10c21782de2412e8a2fefca88ecbf1a
Autor:
Courtney Lunger, Zeli Shen, Hilda Holcombe, Anthony J. Mannion, JoAnn Dzink-Fox, Susanna Kurnick, Yan Feng, Sureshkumar Muthupalani, Sebastian E. Carrasco, Keith T. Wilson, Richard M. Peek, M. Blanca Piazuelo, Douglas R. Morgan, Amanda L. Armijo, Melissa Mammoliti, Timothy C. Wang, James G. Fox
Publikováno v:
Microbiology Spectrum, Vol 12, Iss 1 (2024)
ABSTRACT Helicobacter pylori (H. pylori) causes a cascade from gastritis to gastric neoplasia. During the chronic stages, the oncogenic transcription factor forkhead box protein M1 (FOXM1) becomes increasingly expressed. Given certain strains of the
Externí odkaz:
https://doaj.org/article/0cc4e0cdd03c4002a30d01f014dbcd22
Autor:
Alba Santiago, Amber Hann, Marco Constante, Sara Rahmani, Josie Libertucci, Kyle Jackson, Gaston Rueda, Laura Rossi, Rithwik Ramachandran, Wolfram Ruf, Jon Schertzer, Alberto Caminero, Premysl Bercik, Heather Jean Galipeau, Elena Francisca Verdu
Publikováno v:
Gut Microbes, Vol 15, Iss 1 (2023)
ABSTRACTEmerging evidence implicates microbial proteolytic activity in ulcerative colitis (UC), but whether it also plays a role in Crohn’s disease (CD) remains unclear. We investigated the effects of colonizing adult and neonatal germ-free C57BL/6
Externí odkaz:
https://doaj.org/article/f2241f5e71c64a749f4603783cae0ee6
Autor:
Casey Hensley, Sandro Roier, Peng Zhou, Sofia Schnur, Charlotte Nyblade, Viviana Parreno, Annie Frazier, Maggie Frazier, Kelsey Kiley, Samantha O’Brien, Yu Liang, Bryan T. Mayer, Ruizhe Wu, Celia Mahoney, Monica M. McNeal, Benjamin Petsch, Susanne Rauch, Lijuan Yuan
Publikováno v:
Vaccines, Vol 12, Iss 3, p 260 (2024)
Human rotavirus (HRV) is still a leading cause of severe dehydrating gastroenteritis globally, particularly in infants and children. Previously, we demonstrated the immunogenicity of mRNA-based HRV vaccine candidates expressing the viral spike protei
Externí odkaz:
https://doaj.org/article/cb5a7873ad0641e491f027758ab5b5e0