Sugar coating autophagy: exploring the links between the inhibition of NGLY1 (N-glycanase 1) and autophagy induction

Autor: Holger B. R. Kramer, Sarah Ann Allman

Publikováno v: Autophagy Reports, Vol 2, Iss 1 (2023)

The cytosolic enzyme NGLY1 (N-glycanase 1) is a central mediator of glycoprotein catabolism. The enzyme acts to cleave N-linked glycans from modified substrate asparagine residues prior to degradation of misfolded proteins by the proteasome, playing

Externí odkaz: https://doaj.org/article/47c5ee5fc2fd4679a6bcdc0d52a8a50f

Divergent responses of serum testosterone and cortisol in athlete men after a marathon race

Autor: Claudio E. Kater, Renato Fraga M. Lotufo, Turíbio Leite de Barros Neto, Sheyla Carla A. França, Marisa Cury Agresta

Publikováno v: Arquivos Brasileiros de Endocrinologia & Metabologia, Volume: 50, Issue: 6, Pages: 1082-1087, Published: DEC 2006
Arquivos Brasileiros de Endocrinologia & Metabologia v.50 n.6 2006
Arquivos Brasileiros de Endocrinologia & Metabologia
Sociedade Brasileira de Endocrinologia e Metabologia (SBEM)
instacron:SBEM
Repositório Institucional da UNIFESP
Universidade Federal de São Paulo (UNIFESP)
instacron:UNIFESP

O exercício físico altera a homeostase, pois requer rápida mobilização de fontes metabólicas. Neste estudo, analisamos a resposta dos níveis séricos de testosterona (T) e cortisol (C) e das enzimas de desgaste muscular CK, CKMB e LDH, em 20 a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b835b7527c76d39c704642931619a52c
https://doi.org/10.1590/s0004-27302006000600015

Gene Therapy for Lysosomal Disorders

Autor: L. J. Fairbairn, L. S. Lashford

Publikováno v: Blood Cell Biochemistry ISBN: 9781461372189

The lysosomal storage disorders (LSDs) represent a wide group of clinically diverse types of disorders that include the mucopolysaccharidoses, sphingolipidoses, and defects in glycoprotein catabolism (Neufeld, 1991). All are characterized by the inab

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::06f874c87380fe118859b2491facb2d0
https://doi.org/10.1007/978-1-4615-4889-8_7

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Effects of the ?-mannosidase inhibitors, 1,4-dideoxy-1,4-imino-d-mannitol and swainsonine, on glycoprotein catabolism in cultured macrophages

Autor: Peter F Daniel, P.W. Smith, George W. J. Fleet, Nancy E. O’Neil, David S Newburg

Publikováno v: Glycoconjugate Journal. 6:229-240

Thioglycollate-stimulated murine peritoneal macrophages were cultured for eight days in the presence of swainsonine, or 1,4-dideoxy-1,4-imino-D-mannitol (DIM), or both of these competitive alpha-mannosidase inhibitors together. Analysis of accumulate

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3766835fbf9114f4d10986555f8c5319
https://doi.org/10.1007/bf01050651