Zobrazeno 1 - 10
of 1 198
pro vyhledávání: '"glycogen synthase kinase-3β"'
Autor:
Shujun Yang, Liying Pei, Zijie Huang, Yinsheng Zhong, Jun Li, Yinghui Hong, Huibao Long, Xuxiang Chen, Changqing Zhou, Guanghui Zheng, Chaotao Zeng, Haidong Wu, Tong Wang
Publikováno v:
Molecular Medicine, Vol 30, Iss 1, Pp 1-15 (2024)
Abstract Background Myocardial infarction (MI) leads to enhanced activity of cardiac fibroblasts (CFs) and abnormal deposition of extracellular matrix proteins, resulting in cardiac fibrosis. Tartrate-resistant acid phosphatase 5 (ACP5) has been show
Externí odkaz:
https://doaj.org/article/242d850a424a4905b2a9e4ba2957e691
Autor:
Isabel Atienza-Navarro, Angel del Marco, Maria de los Angeles Garcia-Perez, Alvaro Raya-Marin, Carmen Gil, Ana Martinez, Isabel Benavente-Fernandez, Simon Lubian-Lopez, Monica Garcia-Alloza
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 180, Iss , Pp 117586- (2024)
Germinal matrix-intraventricular hemorrhage (GM-IVH) is one of the most common complications of the preterm newborn. The pathology of the GM-IVH is not completely understood and even regions distant from the lesion area are severely affected. It has
Externí odkaz:
https://doaj.org/article/25f22fb9f82a404a9fd25028dbabb02e
Publikováno v:
Brain and Behavior, Vol 14, Iss 10, Pp n/a-n/a (2024)
ABSTRACT Introduction Alzheimer's disease (AD) is a neurodegenerative disease characterized by Amyloid plaques and neurofibrillary tangles. We explored the potential mechanism by which Danggui Shaoyao San (DSS) modulates central glucose metabolism vi
Externí odkaz:
https://doaj.org/article/64b86846abcc41839e7d2594ed8752ca
Publikováno v:
Frontiers in Endocrinology, Vol 15 (2024)
BackgroundOur previous multicenter case-control study showed that aging, up-regulation of platelet glycogen synthase kinase-3β (GSK-3β), impaired olfactory function, and ApoE ϵ4 genotype were associated with cognitive decline in type 2 diabetes me
Externí odkaz:
https://doaj.org/article/cf78745ad9e04d1a9afe08d051144d12
Publikováno v:
Journal of Dental Sciences, Vol 18, Iss 4, Pp 1534-1543 (2023)
Background/purpose: Cell pyroptosis and gingival inflammation have been implicated in periodontitis progression. Our previous study revealed that AR-A014418, a pharmacological inhibitor of glycogen synthase kinase-3β (GSK-3β), can enhance the migra
Externí odkaz:
https://doaj.org/article/d90a84075ddb40aab6cfeab232713b38
Publikováno v:
Frontiers in Aging Neuroscience, Vol 15 (2023)
BackgroundTau phosphorylation is a pathological hallmark of Alzheimer’s disease (AD). Previously, we reported that the γ-adducin 1–357 fragment is present in the brains of AD patients. However, it remains unknown how γ-adducin regulates tau pho
Externí odkaz:
https://doaj.org/article/d3f8254559dc4cc69f0c8c8a3772f75e
Publikováno v:
Brain Circulation, Vol 9, Iss 3, Pp 162-171 (2023)
BACKGROUND: Glycogen synthase kinase-3β (GSK3β), fat mass and obesity-associated protein (FTO), and toll-like receptors 4 (TLR4) take on critical significance in different biological processes, whereas their interactions remain unclear. The objecti
Externí odkaz:
https://doaj.org/article/dd8442da741a4a2a92c432e9ac3316c6
Publikováno v:
环境与职业医学, Vol 39, Iss 10, Pp 1095-1101 (2022)
BackgroundAluminum (Al) can cause irreversible damage to neurons and synapses function, and the mechanism may be connected to mitochondrial damage caused by glycogen synthase kinase-3β (GSK-3β) regulating dynamin-related protein 1 (DRP1), resulting
Externí odkaz:
https://doaj.org/article/5d1e1e89052f4ffa994804c4d66a03ec
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2023)
Externí odkaz:
https://doaj.org/article/f1da94046e314acb887f460731744b82
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