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pro vyhledávání: '"glun2b"'
Akademický článek
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Publikováno v:
Open Life Sciences, Vol 19, Iss 1, Pp 793-800 (2024)
Externí odkaz:
https://doaj.org/article/09780ab007c6417390a5e3e035f23132
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 18, p 10220 (2024)
N-methyl-D-aspartate receptors (NMDARs) are glutamate receptors with key roles in synaptic communication and plasticity. The activation of synaptic NMDARs initiates plasticity and stimulates cell survival. In contrast, the activation of extrasynaptic
Externí odkaz:
https://doaj.org/article/d007bae4f85a46d9ab54ce36a65a02cd
Autor:
Mengxue Wu, Shilian Xu, Kai Mi, Shuang Yang, Yuanyuan Xu, Jie Li, Junyang Chen, Xiaomin Zhang
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 17 (2024)
IntroductionNeonatal hypoxic-ischemic brain damage (HIBD) refers to brain damage in newborns caused by hypoxia and reduced or even stopped cerebral blood flow during the perinatal period. Currently, there are no targeted treatments for neonatal ische
Externí odkaz:
https://doaj.org/article/ddb8687c0b3a45f3878c599d829c0c85
Autor:
Xiong Wang, Jiazhao Xie, Lu Tan, Yanjun Lu, Na Shen, Jiaoyuan Li, Hui Hu, Huijun Li, Xiaoguang Li, Liming Cheng
Publikováno v:
Translational Neurodegeneration, Vol 12, Iss 1, Pp 1-19 (2023)
Abstract Background Synaptic degeneration occurs in the early stage of Alzheimer's disease (AD) before devastating symptoms, strongly correlated with cognitive decline. Circular RNAs (circRNAs) are abundantly enriched in neural tissues, and aberrant
Externí odkaz:
https://doaj.org/article/2b2f0b20ab494595814f8a09a17d083b
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Publikováno v:
Molecular Neurodegeneration, Vol 18, Iss 1, Pp 1-29 (2023)
Abstract Stroke and late-onset Alzheimer’s disease (AD) are risk factors for each other; the comorbidity of these brain disorders in aging individuals represents a significant challenge in basic research and clinical practice. The similarities and
Externí odkaz:
https://doaj.org/article/e1512064a32a46c7a8810611d864651b
Autor:
Lisheng Cai, Jeih-San Liow, Cheryl L. Morse, Sanjay Telu, Riley Davies, Lester S. Manly, Sami S. Zoghbi, Frederick T. Chin, Robert B. Innis, Victor W. Pike
Publikováno v:
EJNMMI Research, Vol 13, Iss 1, Pp 1-11 (2023)
Key points Question: Do GluN2B radioligands 11C-NR2B-Me enantiomers show cross-binding with σ1 receptors in brain in vivo? Pertinent findings: 11C-(+)-NR2B-Me, 11C-(−)-NR2B-Me, 11C-(S)-NR2B-SMe, and 11C-(R)-NR2B-SMe give specific signals in whole
Externí odkaz:
https://doaj.org/article/0a8dea1580224d03a86adc98e17465ab
Autor:
Chen Jing, Luo Yanmin, Liang Xin, Kong Xiangru, Xiao Qian, Tang Jing, Qi Yingqiang, Tang Yong, Xiu Yun
Publikováno v:
Translational Neuroscience, Vol 13, Iss 1, Pp 379-389 (2022)
N-Methyl-d-aspartate receptor (NMDAR) signaling pathway has been implicated in the pathogenesis and treatment of depression. However, the role of NMDAR subunits in depression is still unclear. In this study, alteration in all seven NMDAR subunits in
Externí odkaz:
https://doaj.org/article/7f97f629dbcf4ef7ad4f1e92ea112a0e
Autor:
Josiah D. Zoodsma, Emma J. Keegan, Gabrielle R. Moody, Ashwin A. Bhandiwad, Amalia J. Napoli, Harold A. Burgess, Lonnie P. Wollmuth, Howard I. Sirotkin
Publikováno v:
Molecular Autism, Vol 13, Iss 1, Pp 1-17 (2022)
Abstract Background Autism spectrum disorder (ASD), like many neurodevelopmental disorders, has complex and varied etiologies. Advances in genome sequencing have identified multiple candidate genes associated with ASD, including dozens of missense an
Externí odkaz:
https://doaj.org/article/9259b7d1d3a848e6991b30c900ffaa4d