Zobrazeno 1 - 10
of 120
pro vyhledávání: '"glucose-stimulated insulin secretion (gsis)"'
Publikováno v:
Diabetes, Metabolic Syndrome and Obesity, Vol Volume 13, Pp 509-520 (2020)
Chunyan Liu, Yanan Hao, Fei Yin, Jianhui Liu Chongqing Key Laboratory of Medicinal Chemistry & Molecular Pharmacology, Chongqing University of Technology, Chongqing 400054, People’s Republic of ChinaCorrespondence: Jianhui Liu; Fei YinChongqing Key
Externí odkaz:
https://doaj.org/article/e0cc8a58a8c0423cafd32b5da2bc7589
Autor:
Hai-Ming Xu, Meng-Yu Wu, Xin-Chen Shi, Ke-Liang Liu, Ying-Chi Zhang, Yin-Feng Zhang, Hong-Mei Li
Publikováno v:
Toxics, Vol 11, Iss 2, p 174 (2023)
This study aimed to investigate the effects of perfluorooctanesulfonic acid (PFOS) exposure on glucose-stimulated insulin secretion (GSIS) of rat insulinoma (INS-1) cells and the potential protective effects of procyanidins (PC). The effects of PFOS
Externí odkaz:
https://doaj.org/article/8ab955a3ab4349efa1d6929389bc61a6
Autor:
Bibek Thapa, Eul Hyun Suh, Daniel Parrott, Pooyan Khalighinejad, Gaurav Sharma, Sara Chirayil, A. Dean Sherry
Publikováno v:
Frontiers in Endocrinology, Vol 12 (2022)
An imaging method for detecting β-cell function in real-time in the rodent pancreas could provide new insights into the biological mechanisms involving loss of β-cell function during development of type 2 diabetes and for testing of new drugs desig
Externí odkaz:
https://doaj.org/article/9d3efc7e2cc640f99933a0f46e2e6e3e
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 9 (2021)
Islet perifusion systems can be used to monitor the highly dynamic insulin release of pancreatic islets in glucose-stimulated insulin secretion (GSIS) assays. Here, we present a new generation of the microfluidic hanging-drop-based islet perifusion p
Externí odkaz:
https://doaj.org/article/b661328e4728456c9147fd07b6a3948a
Autor:
Geetali Pradhan, Jong Han Lee, Chia-Shan Wu, Hongying Wang, Ligen Lin, Taraka Donti, Brett H. Graham, Arun S. Rajan, Ashok Balasubramanyam, Susan L. Samson, Shaodong Guo, Yuxiang Sun
Publikováno v:
Biomolecules, Vol 12, Iss 3, p 407 (2022)
Ghrelin receptor, a growth hormone secretagogue receptor (GHS-R), is expressed in the pancreas. Emerging evidence indicates that GHS-R is involved in the regulation of glucose-stimulated insulin secretion (GSIS), but the mechanism by which GHS-R regu
Externí odkaz:
https://doaj.org/article/33947880003c4b45927751cb57382d2f
Autor:
Emily S. Krueger, Joseph L. Beales, Kacie B. Russon, Weston S. Elison, Jordan R. Davis, Jackson M. Hansen, Andrew P. Neilson, Jason M. Hansen, Jeffery S. Tessem
Publikováno v:
Biomolecules, Vol 11, Iss 12, p 1892 (2021)
Serum accumulation of the gut microbial metabolite trimethylamine N-oxide (TMAO) is associated with high caloric intake and type 2 diabetes (T2D). Impaired pancreatic β-cell function is a hallmark of diet-induced T2D, which is linked to hyperglycemi
Externí odkaz:
https://doaj.org/article/23b267ded2ae44c7a1904afa21bb11a0
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Publikováno v:
Cells, Vol 9, Iss 7, p 1621 (2020)
Glucagon-like peptide-1 (GLP-1) has been shown to potentiate glucose-stimulated insulin secretion binding GLP-1 receptor on pancreatic β cells. β-arrestin 1 (βARR1) is known to regulate the desensitization of GLP-1 receptor. Mounting evidence indi
Externí odkaz:
https://doaj.org/article/571e0e4c566d42b1a8e406666c57a052
Autor:
Bando, Hiroshi
Publikováno v:
Diabetes Research : Open Journal. 8(1):e1-e3
Imeglimin (Twymeeg) is novel oral hypoglycemic agent (OHA) developed in the glimin category. It has dual action mechanisms of reducing insulin resistance and increasing insulin secretion. Trials of imeglimin for efficacy and safety 1 (TIMES 1), TIMES
Akademický článek
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