Zobrazeno 1 - 10
of 131
pro vyhledávání: '"global metabolomics"'
Autor:
Eran Tallis, Cecile L. Karsenty, Amanda B. Grimes, Lina B. Karam, Sarah H. Elsea, Vernon Reed Sutton, Brandy L. Rawls‐Castillo, Ning Liu, Claudia Soler‐Alfonso
Publikováno v:
JIMD Reports, Vol 63, Iss 4, Pp 309-315 (2022)
Abstract Glycogen storage disease type Ib (GSD‐Ib) is a rare inborn error of glycogen metabolism uniquely associated with neutropenia and neutrophil dysfunction, causing severe infections, inflammatory bowel disease (IBD), and impaired wound healin
Externí odkaz:
https://doaj.org/article/50ae9cea9a614d9b90f369eee6453daa
Autor:
Shenglan Jia, Mauricius Marques Dos Santos, Caixia Li, Mingliang Fang, Mithusha Sureshkumar, Shane A. Snyder
Publikováno v:
Environment International, Vol 175, Iss , Pp 107942- (2023)
Bisphenol analogs (BPs) are widely used as industrial alternatives for Bisphenol A (BPA). Their toxicity assessment in humans has mainly focused on estrogenic activity, while other toxicity effects and mechanisms resulting from BPs exposure remain un
Externí odkaz:
https://doaj.org/article/6903acf6812b4019aba384cc5992cf35
Publikováno v:
Frontiers in Molecular Biosciences, Vol 10 (2023)
Externí odkaz:
https://doaj.org/article/065e162c0d2447dda723bd3412300033
Autor:
Jin Shang, Wen Cui, Ruixue Guo, Yiding Zhang, Peipei Wang, Wei Yu, Xuejun Zheng, Ting Wang, Yijun Dong, Jing Zhao, Suying Ding, Jing Xiao, Zhigang Ren, Zhanzheng Zhao
Publikováno v:
Frontiers in Endocrinology, Vol 13 (2022)
ObjectiveDiabetic kidney disease (DKD) is one of the most prevalent complications of diabetes mellitus (DM) and is associated with gut microbial dysbiosis. We aim to build a diagnostic model to aid clinical practice and uncover a crucial harmful micr
Externí odkaz:
https://doaj.org/article/32e58fa7a0a84586ab766970551aaacf
Publikováno v:
Cells, Vol 12, Iss 18, p 2249 (2023)
Intracranial hypertension (ICP) and visual impairment intracranial pressure (VIIP) are some of the sequels of long-term space missions. Here we sought to determine how space microgravity (µG) impacts the metabolomics profile of oligodendrocyte proge
Externí odkaz:
https://doaj.org/article/a6ba3e4e9a54463b91b7cc877d1f3c0b
Autor:
Surender Rajasekaran, Caleb P Bupp, Mara Leimanis-Laurens, Ankit Shukla, Christopher Russell, Joseph Junewick, Emily Gleason, Elizabeth A VanSickle, Yvonne Edgerly, Bryan M Wittmann, Jeremy W Prokop, André S Bachmann
Publikováno v:
eLife, Vol 10 (2021)
Background: Polyamine levels are intricately controlled by biosynthetic, catabolic enzymes and antizymes. The complexity suggests that minute alterations in levels lead to profound abnormalities. We described the therapeutic course for a rare syndrom
Externí odkaz:
https://doaj.org/article/1498a58c840f461ba483dbb1a62257c5
Autor:
Soujanya D. Yelamanchi, Archita Mishra, Santosh Kumar Behra, Gayathree Karthikkeyan, Thottethodi Subrahmanya Keshava Prasad, Avadhesha Surolia
Publikováno v:
Metabolites, Vol 12, Iss 6, p 493 (2022)
Mycobacterium tuberculosis (Mtb) is considered to be a devastating pathogen worldwide, affecting millions of people globally. Several drugs targeting distinct pathways are utilized for the treatment of tuberculosis. Despite the monumental efforts bei
Externí odkaz:
https://doaj.org/article/aecd5128789742649ef6c9ae999b5044
Akademický článek
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Akademický článek
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Publikováno v:
Metabolites, Vol 10, Iss 5, p 186 (2020)
Liquid chromatography coupled to high-resolution mass spectrometry platforms are increasingly employed to comprehensively measure metabolome changes in systems biology and complex diseases. Over the past decade, several powerful computational pipelin
Externí odkaz:
https://doaj.org/article/b8d06dc851e54fe0a60e1d35d1b97366