Zobrazeno 1 - 10
of 40
pro vyhledávání: '"glioma stem cell (GSC)"'
Autor:
Sirong Song, Haiyang Wu, Fanchen Wang, Jiji Jiao, Lixia Xu, Hongguang Wang, Xiaoguang Tong, Hua Yan
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
BackgroundGlioma stem cells (GSCs) are a sub-population of cancer stem cells with capacity of self-renewal and differentiation. Accumulated evidence has revealed that GSCs were shown to contribute to gliomagenesis, distant metastasis as well as the r
Externí odkaz:
https://doaj.org/article/aea3e151ba844c2e8ee2bc37742de5c9
Autor:
Li Guowei, Jin Yanping
Publikováno v:
Frontiers in Neuroinformatics, Vol 16 (2022)
ObjectiveIn our research we try to explore whether glioma stem cell containing circRNAs signal pathway could regulate glioma malignant progression and elaborate its possible mechanism.MethodsIn this study, we used biological information analysis to b
Externí odkaz:
https://doaj.org/article/c5725b39a0bd4085a269104a35fa8fbe
Akademický článek
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Autor:
Byung-Hak Kim, Haeri Lee, Cheol Gyu Park, Ae Jin Jeong, Song-Hee Lee, Kum Hee Noh, Jong Bae Park, Chung-Gi Lee, Sun Ha Paek, Hyunggee Kim, Sang-Kyu Ye
Publikováno v:
Cells, Vol 9, Iss 3, p 722 (2020)
Constitutively activated STAT3 plays an essential role in the initiation, progression, maintenance, malignancy, and drug resistance of cancer, including glioblastoma, suggesting that STAT3 is a potential therapeutic target for cancer therapy. We rece
Externí odkaz:
https://doaj.org/article/98507c931e764ae59a644a3ad0d1ac59
Akademický článek
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Autor:
Courtney L.R. Jurd, Kathleen S. Ensbey, Thomas Robertson, Zara C. Bruce, Paul R. Jamieson, Carolin Offenhäuser, Rochelle C.J. D’Souza, Bryan W. Day, Fiona M. Smith, Andrew W. Boyd, Po Inglis, Rosalind L. Jeffree, Kevin P. Campbell, Seckin Akgul, Yuchen Li, Justin D. Lathia, Zarnie Lwin, Yi Chieh Lim, Jeremy N. Rich, Terrance Grant Johns, Brett W. Stringer, Krishna P.L. Bhat, Ulrich Baumgartner
Publikováno v:
Acta Neuropathologica
Glioblastomas (GBMs) are malignant central nervous system (CNS) neoplasms with a very poor prognosis. They display cellular hierarchies containing self-renewing tumourigenic glioma stem cells (GSCs) in a complex heterogeneous microenvironment. One pr
Publikováno v:
Oncotarget
Glioblastoma resists chemotherapy then recurs as a fatal space-occupying lesion. To improve the prognosis, the issues of chemoresistance and tumor size should be addressed. Glioma stem cell (GSC) populations, a heterogeneous power-law coded populatio
Autor:
Ntlotlang Mokgautsi, Bashir Lawal, Alexander T.H. Wu, Harshita Khedkar, Maryam Rachmawati Sumitra, Hsu Shan Huang, Ya Ting Wen
Publikováno v:
International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 22, Iss 2464, p 2464 (2021)
Volume 22
Issue 5
International Journal of Molecular Sciences, Vol 22, Iss 2464, p 2464 (2021)
Volume 22
Issue 5
Despite management efforts with standard surgery, radiation, and chemotherapy, glioblastoma multiform (GBM) remains resistant to treatment, which leads to tumor recurrence due to glioma stem cells (GSCs) and therapy resistance. In this study, we used
Akademický článek
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Publikováno v:
Oncotarget
Glioblastoma resists chemoradiotherapy, then, recurs to be a fatal space-occupying lesion. The recurrence is caused by re-growing cell populations such as glioma stem cells (GSCs), suggesting that GSC populations should be targeted. This study addres