Zobrazeno 1 - 10
of 186
pro vyhledávání: '"glioblastoma stem cell"'
Autor:
Hao Wang, Lin Yao, Jinming Chen, Yanyan Li, Zuopeng Su, Yongsheng Liu, Wen Li, Yun Xiong, Heyang Gao, Xiao Zhang, Youxin Zhou
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 43, Iss 1, Pp 1-22 (2024)
Abstract Background Glioblastoma (GBM) is an immunosuppressive, universally lethal cancer driven by glioblastoma stem cells (GSCs). The interplay between GSCs and immunosuppressive microglia plays crucial roles in promoting the malignant growth of GB
Externí odkaz:
https://doaj.org/article/e6f60311a081441cbda1e20c8b300e8f
Autor:
Sonia Spinelli, Federica Barbieri, Monica Averna, Tullio Florio, Marco Pedrazzi, Beatrice F. Tremonti, Michela Capraro, Roberta De Tullio
Publikováno v:
Frontiers in Molecular Biosciences, Vol 11 (2024)
Glioblastoma (GBM) is the most malignant brain tumor, characterized by cell heterogeneity comprising stem cells (GSCs) responsible for aggressiveness. The calpain/calpastatin (calp/cast) proteolytic system is involved in critical physiological proces
Externí odkaz:
https://doaj.org/article/5f20c9bee3f74ab68286b8ad4f355e3d
Akademický článek
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Akademický článek
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Akademický článek
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Autor:
Timothy Johanssen, Laura McVeigh, Sara Erridge, Geoffrey Higgins, Joelle Straehla, Margaret Frame, Tero Aittokallio, Neil O. Carragher, Daniel Ebner
Publikováno v:
Frontiers in Oncology, Vol 12 (2023)
Glioblastoma (GBM) remains a cancer of high unmet clinical need. Current standard of care for GBM, consisting of maximal surgical resection, followed by ionisation radiation (IR) plus concomitant and adjuvant temozolomide (TMZ), provides less than 15
Externí odkaz:
https://doaj.org/article/6cf6e85854b04711b730a64dda9229c5
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
Venoms are complex mixtures of different molecules and ions. Among them, bioactive peptides have been found to affect cancer hallmarks, such as cell proliferation, cell invasion, cell migration, and can also modulate the immune response of normal and
Externí odkaz:
https://doaj.org/article/825e6917f6d943bcb15cb0097ee33a74
Autor:
Atsuhito Uneda, Kazuhiko Kurozumi, Atsushi Fujimura, Kentaro Fujii, Joji Ishida, Yosuke Shimazu, Yoshihiro Otani, Yusuke Tomita, Yasuhiko Hattori, Yuji Matsumoto, Nobushige Tsuboi, Keigo Makino, Shuichiro Hirano, Atsunori Kamiya, Isao Date
Publikováno v:
Acta Neuropathologica Communications, Vol 9, Iss 1, Pp 1-23 (2021)
Abstract Glioblastoma (GBM) is the most lethal primary brain tumor characterized by significant cellular heterogeneity, namely tumor cells, including GBM stem-like cells (GSCs) and differentiated GBM cells (DGCs), and non-tumor cells such as endothel
Externí odkaz:
https://doaj.org/article/a0638dbbb3624887941a84049bd7896b
Autor:
Eduardo A. Veliz, Anastasiia Kaplina, Sajini D. Hettiarachchi, Athina L. Yoham, Carolina Matta, Sabrin Safar, Meghana Sankaran, Esther L. Abadi, Emel Kirbas Cilingir, Frederic A. Vallejo, Winston M. Walters, Steven Vanni, Roger M. Leblanc, Regina M. Graham
Publikováno v:
Pharmaceutics, Vol 14, Iss 7, p 1465 (2022)
The current prognosis for glioblastoma is dismal. Treatment-resistant glioblastoma stem cells (GSCs) and the failure of most drugs to reach therapeutic levels within the tumor remain formidable obstacles to successful treatment. Chalcones are aromati
Externí odkaz:
https://doaj.org/article/e8985b1057ce471ca50d4e7b774a1aad
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Glioblastoma (GBM) is the most common and malignant primary brain tumor. Glioblastoma stem cells (GSCs) not only initiate and sustain uncontrolled cell proliferation but also resistant to conventional clinical therapies including temozolomide (TMZ) d
Externí odkaz:
https://doaj.org/article/090cc121c7454e3faa918e3cc8ae67fb