Zobrazeno 1 - 10
of 2 929
pro vyhledávání: '"glioblastoma cells"'
Autor:
Siti Nazihahasma Hassan, Abdul Aziz Mohamed Yusoff, Zamzuri Idris, Norhanani Mohd Redzwan, Farizan Ahmad
Publikováno v:
Future Journal of Pharmaceutical Sciences, Vol 10, Iss 1, Pp 1-9 (2024)
Abstract Background Nutrient stress (NS), one of the hallmarks of the tumour microenvironment, can render cancer cells tolerant to cytotoxicity. Fibroblasts, on the other hand, have cancer cell-like traits, such as plasticity and resiliency. Hence, t
Externí odkaz:
https://doaj.org/article/3348baa3291340848c54e8cccff22d52
Publikováno v:
Biotechnologia Acta, Vol 17, Iss 2, Pp 67-69 (2024)
Aim. The purpose of the study was to investigate the impact of graphene oxide nanoparticles on the expression of a subset of ER stress-dependent genes in normal human astrocytes in comparison with glioblastoma cells depending on the knockdown of ERN1
Externí odkaz:
https://doaj.org/article/b3c78d8f2f0141b993551f8552ce8b4c
Autor:
Minchenko Oleksandr H., Abramchuk Anastasiia I., Khita Olena O., Sliusar Myroslava Y., Viletska Yuliia M., Minchenko Dmytro O.
Publikováno v:
Endocrine Regulations, Vol 58, Iss 1, Pp 206-214 (2024)
Objective. Carboxypeptidase E (CPE) plays an important role in the biosynthesis of neurotransmitters and peptide hormones including insulin. It also promotes cell proliferation, survival, and invasion of tumor cells. The endoplasmic reticulum stress,
Externí odkaz:
https://doaj.org/article/3009a13843a6451d8b39bd696d3a6145
Autor:
Minchenko Oleksandr H., Sliusar Myroslava Y., Khita Olena O., Minchenko Dmytro O., Viletska Yuliia M., Halkin Oleh V., Levadna Liudmyla O., Cherednychenko Anastasiia A., Khikhlo Yevgen P.
Publikováno v:
Endocrine Regulations, Vol 58, Iss 1, Pp 91-100 (2024)
Objective. Glucose and glutamine supply as well as serine synthesis and endoplasmic reticulum (ER) stress are important factors of glioblastoma growth. Previous studies showed that the knockdown of ERN1 (ER to nucleus signaling 1) suppressed glioblas
Externí odkaz:
https://doaj.org/article/fe2223a129ea40ada897520c36364990
Autor:
Krasnytska Daria A., Khita Olena O., Viletska Yuliia M., Minchenko Dmytro O., Halkin Oleh V., Rudnytska Olha V., Hoian Sofiia L., Minchenko Oleksandr H.
Publikováno v:
Endocrine Regulations, Vol 58, Iss 1, Pp 47-56 (2024)
Homeobox genes play an important role in health and disease including oncogenesis. The present investigation aimed to study ERN1-dependent hypoxic regulation of the expression of genes encoding homeobox proteins MEIS (zinc finger E-box binding homeob
Externí odkaz:
https://doaj.org/article/f7aa9d84f6224def9fd6df5e506bf5f0
Autor:
Fernanda Ferreira Mendonça, Alice Santos de Miranda, Henrique Massao Achidate Makino, Lorena Marinelli Mendes, Danielle Vieira Sobral, Marycel Figols de Barboza, Luciana Malavolta, Leonardo Lima Fuscaldi
Publikováno v:
Hematology, Transfusion and Cell Therapy, Vol 46, Iss , Pp S10-S11 (2024)
Introduction/Justification: Peptides are implicated in various physiological responses and hold significant potential as targeting molecules, especially in cancer diagnosis or treatment. Radiolabeled peptides have been investigated for their potentia
Externí odkaz:
https://doaj.org/article/d56a06a43a9242fbbca72039e7dc90d4
Autor:
Adriana de Souza Andrade, Sofia Oliveira Campos, Jamile Dias, Marco Antônio Campos, Erna Geessien Kroon
Publikováno v:
Virology Journal, Vol 20, Iss 1, Pp 1-13 (2023)
Abstract Background Dengue virus (DENV) is a Flaviviridae member classified into four antigenically distinct serotypes (DENV 1, 2, 3, and 4) and further subdivided genotypes. DENV3 is subdivided into four or five genotypes, depending on the classific
Externí odkaz:
https://doaj.org/article/0854f362cff544958e5171dc1aa004ca
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 15, p 8270 (2024)
Glioblastoma multiforme is the most common and fatal brain tumor among human cancers. Ceramide (Cer) and Sphingosine 1-phosphate (S1P) have emerged as bioeffector molecules that control several biological processes involved in both cancer development
Externí odkaz:
https://doaj.org/article/7ea527317c014e76bbcc7aae275e8ebc
Autor:
Sara Ragucci, Veronica Russo, Angela Clemente, Maria Giuseppina Campanile, Maria Antonietta Oliva, Nicola Landi, Paolo Vincenzo Pedone, Antonietta Arcella, Antimo Di Maro
Publikováno v:
Toxins, Vol 16, Iss 3, p 135 (2024)
Ribosome inactivating proteins (RIPs) are specific N-β-glycosylases that are well-characterized in plants. Their enzymatic action is to damage ribosomes, thereby blocking protein translation. Recently, several research groups have been working on th
Externí odkaz:
https://doaj.org/article/e7a087fef7704ca198f92b27657697e8
Autor:
Minchenko Dmytro O., Rudnytska Olha V., Khita Olena O., Kulish Yuliia V., Viletska Yuliia M., Halkin Oleh V., Danilovskyi Serhiy V., Ratushna Oksana O., Minchenko Oleksandr H.
Publikováno v:
Endocrine Regulations, Vol 57, Iss 1, Pp 162-172 (2023)
Objective. Single-walled carbon nanotubes (SWCNTs) are considered to be one of the nanomaterials attractive for biomedical applications, particularly in the health sciences as imaging probes and drug carriers, especially in the field of cancer therap
Externí odkaz:
https://doaj.org/article/18a811d499954a08a86a5931c08b6421