Cladogynos orientalis Zipp. extracts inhibit cell culture-derived hepatitis C virus genotype 2a replication in Huh-7 cells through NS5B inhibition

Autor: Piyanoot Thongsri, Khanit Sa-ngiamsuntorn, Pongtip Sithisarn, Mullika T Chomnawang, Krit Thirapanmethee

Publikováno v: Asian Pacific Journal of Tropical Biomedicine, Vol 9, Iss 8, Pp 346-352 (2019)

Objective: To evaluate the potential anti-hepatitis C virus (HCV) activities of Cladogynos orientalis Zipp. ex Span and to investigate the molecular mode of action. Methods: Ethanolic and water extracts from various parts of Cladogynos orientalis wer

Externí odkaz: https://doaj.org/article/200ad351b07d49448f7d2a2edcbf0a66

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A Recombinant Hepatitis C Virus Genotype 1a E1/E2 Envelope Glycoprotein Vaccine Elicits Antibodies That Differentially Neutralize Closely Related 2a Strains through Interactions of the N-Terminal Hypervariable Region 1 of E2 with Scavenger Receptor B1

Autor: Janelle Johnson, Darren Hockman, John Lok Man Law, Michael Houghton, D. Lorne Tyrrell, Jason Wong, Holly Freedman, Michael R. Beard, Jianqi He, Thomas F. Baumert, Chao Chen, Michael Logan, Nicholas S. Eyre

Publikováno v: Journal of Virology
Journal of Virology, American Society for Microbiology, 2019, 93 (22), ⟨10.1128/JVI.00810-19⟩
Journal of Virology, 2019, 93 (22), pp.e00810-19. ⟨10.1128/JVI.00810-19⟩

A vaccine is still urgently needed to overcome the hepatitis C virus (HCV) epidemic. It is estimated that 1.75 million new HCV infections occur each year, many of which will go undiagnosed and untreated. Untreated HCV can lead to continued spread of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc9ed9610396a2092674556b7c486488
https://hal.archives-ouvertes.fr/hal-02385651

Regulação da expressão de proteínas de choque térmico pelo vírus da hepatite C

Autor: Braga, Ana Claudia Silva [UNESP]

Publikováno v: Repositório Institucional da UNESPUniversidade Estadual PaulistaUNESP.

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Externí odkaz: http://hdl.handle.net/11449/151515

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